Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/9

Click to flip

9 Cards in this Set

  • Front
  • Back
why can't we develop vaccines to parasites?
difficult to develop longterm immunity to parasites because of their diverse life cycle
nonspecific response to parasites
EOSINOPHILS and mast cells (degranulation attacks cuticle)
complement: if have PM (protozoans) can form MAC; MAC not effective on helminth but can still opsonize
phagocytes- protozoans and helminth larvae
specific response to parasites
TH1: DTH, CTL, ADCC (intracell)

TH2: opsonization, C' activation, ADCC (extracell)
Leishmania species: general charac
flagellated protozoan
reservoirs: dogs, cats, rodents, humans
transmission: sand-fly (arthropod)
Leishmania species: clinical disease
cutaneous: L.Tropica- ulcerating skin sores
heal with scars b/c bystander damage

mucocutaneous: L.braziliensis- extreme damage due to immune response (destruction of cartilage and skin)

visceral: L.donovanni
prevention, resolution leishmania species
innate- inflamm
adaptive-
prevention:memory DTH to 2ndary infection (not primary)
opsonizing Ig-if dont downreg TH1, block adherence before establish 2ndary infection
resolution-DTH and strong TH1
taenia saginata: general charac
helminth: beef tapeworm
transmission-ingest larvae in raw beef
host-humans are definitive host (adult and sexual life)
clinical disease: taenia saginata
infects intestines
most infections asymptomatic
disease: anorexia (due to obstruction) and diarrhea
prevention and resolution:Taenia saginata
innate- inflamm (eosinophils)
adaptive-
prevention: memory DTH? MPh can phagocytize fragments from degraulation
resolution: NOT POSSIBLE; TRYO TO CONTROl BURDEN
TH1 and strong cell mediated-self limiting
TH2-disseminated