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30 Cards in this Set
- Front
- Back
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What is an immune complex
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an antigenic particle with one or more antibodies attached to it
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This class of antibodies comprises 80% of total antibodies in circulation
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IgG
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This class of antibodies is not detectable in circulation
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IgD
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This class of antibodies provides primary defense in local infections
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IgA
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This class of antibodies has five antibody subunits bound together
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IgM
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This class of antibodies has two antibody subunits
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IgA
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This class of antibodies are commonly found in secretions
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IgA
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This class of antibodies comprises 13% of total antibodies in circulation
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IgA
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This class of antibodies comprises 6% of circulation antibodies
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IgM
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Many blood group antibodies are inThis class of antibodies
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IgM
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This class of antibodies stays attached to B cells to serve as an antigen receptor
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IgD
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This class of antibodies can cross the placenta and enter fetal circulation
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IgG
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This class of antibodies Fc portion binds to mast cells
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IgE
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This class of antibodies are seen in patients with parasitic infections
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IgE
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This class of antibodies are seen in patients with respiratory allergies
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IgE
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This class of antibodies are single antibody subunit and is not detectable in circulation
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IgE
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This classes of antibodies does not fix complement
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IgE, IgA, and IgD
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This class of antibodies is excellent at fixing complement
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IgM
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This class of antibodies is good at binding complement
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IgG
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How many antibody subunits does IgG have
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sing antibody subunit
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this can stimulate a b cell to divide and produce IgM antibodies
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T-independent antigens
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This is when B cells do not require cytokines stimulation by T cells. This antigen can stimulate B cells to divide and produce IgM antibodies
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T-independent antigens
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B cells are stimulated by antigen stimulated T cell cytokines
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T dependent antigen
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this type of antigen is usually a processed foreign protein presented on a MHC molecule by antigen presenting cells
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T dependent antigen
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How is complement mainly activated
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by antigen-antibody reactions leading to the formation of C3b
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What is complement
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a group of at least 20 immunologically distinct proteins involved in the complement cascade
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Opsonization and complement function
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phagocytic cells have C3b receptors therefore, C3b stimulates phagocytosis
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What is MAC
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Membrane attack complex it is a function of complement
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C3b leads to the formation of what?
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C5, C6, C7, C8 and C9 this complex is know as MAC or C5-C9 MAC
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What can MAC do for complement
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it is able to puncture a hole in the membrane of the target cell
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