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25 Cards in this Set

  • Front
  • Back
What are the 3 responses to immune process
1. Inflammation
2. Antibody-mediated immunity (humoral immunity) or AMI
3. Cell mediated immunity or CMI
______ can occur without infection
Inflammation
Cardinal signs of inflammation
1. Warmth
2. Redness
3. Swelling
4. Pain
5. Decreased function
What are the cell types involved in inflammation (all leukocytes)
Neutrophils
Macrophages/ Monocytes
Eosinophils
Basophiles
Account for about 67% of WBC's
Takes about 12-14 days to mature
Live about 12-18 hours
Not self renewing
Neutrophils
Account for about 3% of WBC's
Can live for months to years
Can be involved in multiple episodes of phagocytosis
Nonspecific- fight several types
Monocytes
Account for about 1.5% of WBC's
Elevate in an allergic reaction
Eosinophils
Account for about 0.5% of WBC's
Responsible for S/S of inflammation
Release chemicals like: Heparin, Histamine, and Kinis
Basophils
What involves antigen - antibody interaction to destroy foreign proteins
Antibody-Mediated immunity
Most active AMI
Specific - fight specific diseases
Have a memory- not the same cold more than once
B lymphocytes
When we form our own antibodies, long term immunity
Active
When the antibodies are present, but you did not make them
Passive
When you are exposed to the disease in your environment
Natural
When you are purposely exposed to the disease
Artificial
Does not involve antibodies
The lymphocyte with the most active roll is the t-lymphocyte
Cells involved are: helper/inducer T cells (CD4), Suppressor T (CD8), cytotoxic/cytolytic T cells
Cell Mediated Immunity
Formed from stem cells in the bone marrow
Relieased into the blood stream
Mature in the thymus and in lymph nodes
T-lymphocytes
Recognize self from non-self
Help to stimulate production and function of cells involved in immune responses
In HIV this cell is infected
Dx of AIDS if these are less than 200
Helper/Induced T cells
CD4
Prevent overrecations (hypersensitivity reactions)
Prevent formation of antibodies against self (such as autoimmune disorders)
These cells keep us "in check"
Suppressor T Cells
CD8
Subset of suppressor cells
Most effective against parasitic organisms such as viruses, protozoa
Responsible for rejection of transplated oragans and tissues
Cytotoxic/Cytolytic T Cells
"Seeking and Destorying" cells
Most effective against viruses and cancer cells
Responsible for rejection of transplanted organs/tissues
Natural Killer Cells
This causes disease

Carrier of a disease

Anything that can carry disease
Pathogen

Vector

Fomite
Condition that effects alot of people at the same time in the same area

Condition that is local with low mortality rates

Global problem
Epidemic


Endemic


Pandemic
Frequency of a bug and how strong it is
Virulence
Death rate

Number of disease in an area
Mortality

Morbidity
Have the problem but not causing trouble

Contagious
Colonization

Communicable