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25 Cards in this Set
- Front
- Back
What are the 3 responses to immune process
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1. Inflammation
2. Antibody-mediated immunity (humoral immunity) or AMI 3. Cell mediated immunity or CMI |
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______ can occur without infection
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Inflammation
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Cardinal signs of inflammation
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1. Warmth
2. Redness 3. Swelling 4. Pain 5. Decreased function |
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What are the cell types involved in inflammation (all leukocytes)
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Neutrophils
Macrophages/ Monocytes Eosinophils Basophiles |
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Account for about 67% of WBC's
Takes about 12-14 days to mature Live about 12-18 hours Not self renewing |
Neutrophils
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Account for about 3% of WBC's
Can live for months to years Can be involved in multiple episodes of phagocytosis Nonspecific- fight several types |
Monocytes
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Account for about 1.5% of WBC's
Elevate in an allergic reaction |
Eosinophils
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Account for about 0.5% of WBC's
Responsible for S/S of inflammation Release chemicals like: Heparin, Histamine, and Kinis |
Basophils
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What involves antigen - antibody interaction to destroy foreign proteins
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Antibody-Mediated immunity
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Most active AMI
Specific - fight specific diseases Have a memory- not the same cold more than once |
B lymphocytes
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When we form our own antibodies, long term immunity
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Active
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When the antibodies are present, but you did not make them
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Passive
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When you are exposed to the disease in your environment
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Natural
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When you are purposely exposed to the disease
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Artificial
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Does not involve antibodies
The lymphocyte with the most active roll is the t-lymphocyte Cells involved are: helper/inducer T cells (CD4), Suppressor T (CD8), cytotoxic/cytolytic T cells |
Cell Mediated Immunity
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Formed from stem cells in the bone marrow
Relieased into the blood stream Mature in the thymus and in lymph nodes |
T-lymphocytes
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Recognize self from non-self
Help to stimulate production and function of cells involved in immune responses In HIV this cell is infected Dx of AIDS if these are less than 200 |
Helper/Induced T cells
CD4 |
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Prevent overrecations (hypersensitivity reactions)
Prevent formation of antibodies against self (such as autoimmune disorders) These cells keep us "in check" |
Suppressor T Cells
CD8 |
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Subset of suppressor cells
Most effective against parasitic organisms such as viruses, protozoa Responsible for rejection of transplated oragans and tissues |
Cytotoxic/Cytolytic T Cells
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"Seeking and Destorying" cells
Most effective against viruses and cancer cells Responsible for rejection of transplanted organs/tissues |
Natural Killer Cells
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This causes disease
Carrier of a disease Anything that can carry disease |
Pathogen
Vector Fomite |
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Condition that effects alot of people at the same time in the same area
Condition that is local with low mortality rates Global problem |
Epidemic
Endemic Pandemic |
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Frequency of a bug and how strong it is
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Virulence
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Death rate
Number of disease in an area |
Mortality
Morbidity |
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Have the problem but not causing trouble
Contagious |
Colonization
Communicable |