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14 Cards in this Set
- Front
- Back
moderately elevated alk phos
but minimally elevated AST & ALT |
primary biliary cirrhosis
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which markers are on the abnl cells of CLL?
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In CLL, abnl cells are like B cells and thus have CD19 & 20
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NADPH oxidase deficiency
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NADPH oxidase converts NADPH==>superoxide
then superoxide dismutase converts superoxide==>H2O2 (req for resp burst) no NADPH oxidase ==>superoxide ==>no H2O2 ==>no resp burst |
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what pathogens can trigger Reiters?
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Campylobacter jejuni
Chlamydia trachomatis Salmonella Shigella Yersinia |
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nl #B cells but decr plasma cells and decr Ig
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common variable immunodeficiency
(idiopathic dysfxn of B cells)- acquired rather than genetic |
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in AIDS pt w/CD4 count=30, why can Ig for envelope proteins continue until his death, while Ig to internal structural proteins disappear?
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Envelope proteins of HIV virus are always changing, and thus req IgM. Internal structural proteins are constant and thus have been around for a while and req IgG.
T cells are needed to make IgG, but not to make IgM. Thus, AIDs pts with low CD4 T cells can still make IgM against envelope proteins. |
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transplant from one identical twin to another is called
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syngeneic graft
(autograft is only for one person to himself) |
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-active immunity
--natural active immunity --artificial active immunity -passive immunity --natural passive immunity --artificial passive immunity |
active immunity=person makes his own Ig
natural active immunity=person contracted dz himself and makes his own Ig artificial active immunity=person is given vaccin (i.e. DTaP) and then makes his own Ig against it -passive immunity=person is given Ig --natural passive immunity=the Ig that fetus receives via placenta --artificial passive immunity=inject Ig into person |
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what heart prob can rheumatic fever cause?
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MS
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multinulceated giant cells w/eosinophilic cytoplasmic and nuclear inclusion bodies-
indicates what dz |
Measles
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rheumatic dz
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=rheumatic fever
-sequelae of GAS (Strep pyogenes) -Type II hypersensitivity: Anti-Strep Ig cross-react with (and bind, thus Type II) cardiac and joint tissue ==>pancarditis (endocarditis, pericarditis), including Mitral stenosis ==>arthritis ==>subcutaneous nodules |
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autoantibodies in Sjogren's
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Rheumatoid (anti-IgG)
Anti-Ro (anti-SSA) Anti-La (anti-SSB) ANA |
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"ring enhancing lesions" on CT scan
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toxoplasmosis (intracellular parasite)==>thus eliminated by cell-mediated response (Th1)
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cell-mediated response involves which T cell
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Th1
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