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27 Cards in this Set
- Front
- Back
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Why do Viruses cause Diarrhea?
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-Viruses preferentially Affect older, fully differentiate epithelial cells
-Causes stunting of villi -Younger cells are not efficient at absorption -Malabsorptive Diarrhea |
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What type of Viruses are Noroviruses?
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-ssRNA
-Non-enveloped |
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What type of Virus is ssRNA and Non-enveloped?
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Noroviruses
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What results from Noroviruses?
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-Malabsorptive Diarrhea
-Vomitting |
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What advantage does being Non-enveloped give Noroviruses?
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They can Survive the gut
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Why are Antibodies often not Protective against Noroviruses?
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Mutates quick as hell
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What is so fucking scary about Noroviruses?
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-Have you ever been to Norwalk, Ca? Scary place
-They are extremely contagious -Mutate quick, quick, quick as hell |
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Noroviruses have an ID50 of ~10 particles. What does this mean?
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They are highly contagious
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Why are Noroviruses so Contagious?
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-Low ID50
-Shed Virus for a Long Time -Resists Wide Range of Temperatures -Persists in the Environment -Variation |
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What is the leading cause of hospitalization in Children?
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Rotavirus
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What type of Virus is Rotavirus?
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-Non-enveloped
-dsRNA |
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What does Rotavirus cause?
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Malabsorptive Diarrhea
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What is the treatment for Rotavirus?
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Oral Rehydration
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When are Rotavirus Infections the highest?
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Summer
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What is the leading cause of Death in the World?
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Rotaviruses
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What type of Virus is Hepatitis A?
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-Non-enveloped
-ssRNA |
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Which Virus(es) is/are:
-Non-enveloped, ssRNA -Non-enveloped, dsRNA |
-Heptatitis A and Noroviruses
-Rotavirus |
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What is the Incubation time for Hep A?
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1 Month
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What Symptoms will a Child Infected with Hepatitis A typically show? What about an Adult?
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-Usually nothing
-Jaundice |
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What problems result from Hep A infection?
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-Jaundice
-Liver Problems -Urine Discoloration (Light and Dark) |
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How Heptatitis A Transmitted?
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-Human-Specific Virus
-Food-borne Transmission |
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How does Heptatitis A invade?
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-Invades Intestinal Epithelium Cells
-Travels to the Liver -Replicates in Hepatocytes -Passes through Gallbladder -Shed in Feces for several Weeks |
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Why would you want run an IgM ELISA for Hep A?
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-IgM is the 1st Ab seen
-If they body has switched to IgG, that means they have probably cleared it and are immune or have been vaccinated |
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How is Heptatitis B transmitted?
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Blood or Sex
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How is Heptatitis C transmitted?
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Blood
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What does Heptatitis B cause?
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-Chronic and Acute Hepatitis
-Hepatocellular Carcinoma |
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What does Heptatitis C cause?
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-Chronic Liver Disease
-Hepatocellular Carcinoma |
