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78 Cards in this Set
- Front
- Back
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hypoTH - most common cause
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hashimoto's (AI)
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hypoTH - more common in
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females
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hypoTH - 2 other causes
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iodine deficiency
post thyroidectomy |
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hypoTH - clin man
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thin hair
brittle nails bradycardia delayed DTR |
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hypoTH - dx
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high TSH
low T4 |
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hypoTH - mgmt
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levo - start at 25 mcg and move up
more in obese less in elderly |
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hyperTH - most common cause
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graves
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hyperTH - graves /t
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autoantibodies to gland
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hyperTH - age onset
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20 to 40 in women
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hyperTH - clin man
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everything unregulated
pretibial myxedema exophthalmos lid lag hyperreflexia |
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hyperTH - labs
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low TSH
high T3/T4 |
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hyperTH - tx
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propanolol - not in CHF
thioureas - safe in pg radioactive iodide - avoid in pg surgery - preferred in pg |
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hyperTH - 3 other causes
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pg
subclinical thryoiditis amiodarone |
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TH=thyroiditis
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TH
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TH - chronic aka
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hashimoto's
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TH - chronic incidence
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common in females and familial
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TH - chronic clin man
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fatigue
dry mouth and eye enlarged, firm thyroid |
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TH - chronic tx
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levo
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TH - subacute incidence
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young to middle age females
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TH - subacute origin
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viral
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TH - subacute clin man
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painful, enlarged thyroid
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TH - mgmt
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ASA for pain and inflammation
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TH - acute aka
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suppurative
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TH - acute etiology
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caused by pyogenic bacteria
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TH - acute clin man
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very painful, tender, red, enlarged thyroid
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TH - acute mgmt
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abx
surgical drainage if necessary |
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TH - riedels clin man
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stony hard thyroid
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TH - riedels clin man
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dysphagia
dyspnea hoarseness pain |
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TH - riedels mgmt
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steroids
tamoxifen |
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TH - elderly levels
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may drift slightly upward, but stay wnl
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TH - elderly diurnal variation
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goes away
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hypoTH - elderly inc
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common 5-15%
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hypoTH - elderly sx
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fewer classic
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hypoTH - elderly how discovered
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usually unmasked by other illness
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hypoTH - elderly overt mgmt
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always treat
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hypoTH - elderly subclinical >10
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treat whether asx or not
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hypoTH - subclinical
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high TSH, normal T4
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hypoTH - subclinical > 4.5
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treat if sx
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hypoTH - subclinical > 85 yo
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don't treat 4.5-10
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hypoTH - elderly therapy guided by
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TSH
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hypoTH - elderly meds
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elderly requires less, obese require more
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hypoTH - elderly when to take
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empty stomach
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hyperTH - elderly inc
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less common
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hyperTH - elderly sx
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fewer classic
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hyperTH - elderly most prominent sx
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negative
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hyperTH - elderly complications
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CV more common
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hyperTH - elderly mgmt
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propylthiouracil until euthyroid
radiation ablation rarely surgery |
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hyperTH - elderly a fib inc
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20% of elderly
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hyperTH - elderly a fib rate control
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beta blockers only
digoxin won't work warfarin indicated |
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hyperTH - elderly a fib
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generally remits after euthryroid
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HC=hypercholesterolemia
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HC
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HC - linked to
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development of atherosclerosis
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HC - d/t
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elevations in LDL
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HC - etiologies (4)
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familial
nephrotic syndrome hypothyroidism obstructive liver dz |
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HC - clin man
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xanthomas on achilles tendon, patellar tendon, and extensor tendons on hand
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HC - mgmt
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dietary
bile binding agents statins niacin |
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HT=hypertriglyceridemia
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HT
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HT - linked to
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development of pancreatitis
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HT - etiology
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familial
DM uremia sepsis obesity SLE ETOH |
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HT - clin man
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asx
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HC - normal levels
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cholesterol < 200
LDL < 100 (unless CV) HDL > 60 triglycerides < 150 |
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HC - borderline levels
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cholesterol 200-239
LDL 130-159 triglycerides 150-500 |
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HC - unacceptable
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cholesterol >240
LDL >160 HDL < 35 triglycerides > 500 |
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HC - framingham risk score
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indicates risk of having a CV event within the next 10 years
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HC - framingham score at which action is demanded
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20%
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HC - LDL first line DOC
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statins
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HC - statin concerns
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liver enzymes
myopathy |
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HC - risk factors for CHD
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age (45m or 55f)
fam hx of events 1st degree <55 m or 65 f htn 140 or 90 hdl < 40 cigs within last month |
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HC - bile acid sequestrate effects
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decr LD
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HC - bile acid side effects
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GI
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HC - nicotinic acid effects
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incr HDL***** most effective, decr triglycerides
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HC - nicotinic acid side effects
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flushing and hepatotoxicity
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HC - fibric acid effects
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decr triglycerides *****most effective
incr HDL |
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HC - fibric acid side effects
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GI
myopathy, esp with statins |
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HC - omega 3
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decr triglycerides
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HC - nicotinic acid moa
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inhibits release of ffa from adipose and synthesis in liver
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HC - bile acid moa
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resins bind bile acid and cause them to excrete in feces
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HC - statin moa
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inhibit conversion of HMG-CoA to mevalonic acid and subsequently cholesterol
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