Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
12 Cards in this Set
- Front
- Back
|
What is the first line of defence against pathogens? |
Barrier Immunity! |
|
|
What are the 4 main ways that pathogens can enter the body? |
1. Skin breach 2. GI tract 3. Respiratory tract 4. Genito-urinary tract |
|
|
The large absorptive surfaces of the intestine and lungs means that these area are susceptible to pathogen entry. What protective mechanism is present to protect these large surfaces? |
This fragility is compensated by the secretion of mucous onto the fragile surfaces. Moist mucous is effective at trapping small dust particles and droplets containing bacteria or the spores of yeast and fungi. |
|
|
How does cystic fibrosis increase susceptibility to infection? |
Barrier antimicrobial peptide mechanisms highly sensitive to salt |
|
|
Does asthma increase susceptibility to infection? If so, how? |
a |
|
|
As a form of barrier immunity, the mouth and pharynx and upper part of the oesophagus are protected by ......... ? |
Stratified squamous epithelium |
|
|
What is Kartagener's |
Ciliary dysfunction disease, an inability to move bacteria away from lower airways |
|
|
What is the function of mast cells? |
Release factors which increase blood flow and vascular permeability bringing components of immunity to the site of infection |
|
|
True or False Basophils are phagocytic |
False. Basophils, although a part of the granulocyte family, do not contain lysosomal enzymes. |
|
|
List out three functions of dendritic cells ? |
1. Process and present antigen on MHC class I and II molecules to the T cells 2. Migrate towards the T rich area in the secondary lymphoid organ where naive and memory T cell recirculate, here DC present antigen to specific T cells 3. Releases danger signals through molecules like toll receptors that help determine the type of T cell that is programmed |
|
|
Kupffer cells in the liver is a type of immune cell. What type of cell are kupffer cells? |
Kupffer cells are macrophages |
|
|
True or false NK cells is antigen specific and will release toxic chemicals when it encounters its specific antigen |
False. NK cells do not have antigen specific receptors |
