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21 Cards in this Set
- Front
- Back
- 3rd side (hint)
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family for HAV
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Picornavirus
+ss RNA, naked |
A-
B- Hepadena C- Flavi D- (delta) E- unclassified toga |
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family for HBV
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Hepadena
ONLY DNA ico, enveloped, ds, circular |
A- Picorna
B- C- Flavi D- (delta) E- unclassified toga |
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family for HCV
|
Flavi
+ss RNA, enveloped, linear |
A- picorna
B- Hepadena C- D- (delta) E- unclassified toga |
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family for HDV
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"delta"
+ss RNA, linear |
A- picorna
B- Hepadena C- Flavi D- E- unclassified toga |
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family for HEV
|
unclassified toga
+ss RNA, linear |
A- picorna
B- Hepadena C- Flavi D- (delta) E- |
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presentation of HAV
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fecal/oral transmission
no chronic or carrier |
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presentation of HBV
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sexual or parenteral
chronic & oncogenic |
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presentation of HCV
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sexual or parenteral
chronic & oncogenic |
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presentation of HDV
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requires HBV to replicate
parenteral transmission |
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presentation of HEV
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fecal/oral
dangerous if pregnant |
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Implication of positive HBsAg
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surface antigen
active viremia |
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implication of positive HBcAg
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core antigen
found on capsid |
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implication of HBeAg
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envelope antigen
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implication of HBsAB
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protective after virus gone
(vacinated) |
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implication of HBcAB
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not protective
confirm infection during window period |
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Implication of HBeAB
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antibody to envelope
low risk of infectivity |
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Isosporiasis
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chronic intestinal infection in AIDs
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genes in HIV (& gene product)
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GAG- viral core proteins
Env- viral envelop prots Pol- reverse transcriptase |
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proteins in HIV
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reverse transcriptase
p18 & p24 |
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mechanism of infection in HIV
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infects MPs via CCR5 (receptor)
MP acts as reservoir decreased IL-1 secretion, less Ag presentation high mutation rate enters T's via CXCR4 binding to gp120 on virus (gp41 is anchor) budding kills T cell decrease response to Ag, less IL-2 & IFN gamma |
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initial response in HIV infection
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robust CD8 response initially
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