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32 Cards in this Set
- Front
- Back
T20
1. generic 2. brand 3. class of 4. special |
1. enfuvirtide
2. Fuzeon 3. entry inhibitor 4. Painful injections only with salvage regimen |
|
MVC
1. generic 2. brand 3. class 4. Special |
1. maraviroc
2. Selzentry 3. entry inhibitor CCR5 receptor antagonist 4. Trofile testing profile needed only use with R5 virus |
|
RAL
1. generic 2. brand 3. class 4. sides |
1. raltegravir
2. Isentress 3. raltegravir 4. Stevens-Johnson Syndrome, toxic epidermal necrolysis, renal failure |
|
ATV
1. generic 2. brand 3. class 4. sides |
1. atazanavir
2. Reyataz 3. Protease inhibitor 4. Increased risk of nephrolithiasis, Stevens-Johnson Syndrome, toxic epidermal necrolysis, erythema multiforme |
|
FPV
1. generic 2. brand 3. class 4. sides |
1. fosamprenavir
2. Lexiva 3. Protease inhibitor 4. High pill burden, low potency 5. Stevens-Johnson syndrome, neutropenia, nephrolithiasis |
|
DRV
1. generic 2. brand 3. class 4. special 4. disadvantage |
1. darunavir
2. Prezista 3. Protease inhibitor 4. Highest genetic barrier to resistance 5. Weak sulfa |
|
IDV
1. generic 2. brand 3. class 4. Sides |
1. indinavir
2. Crixivan 3. Protease inhibitor 4. Nephrolitihiasis |
|
LPV/RTV (r)
1. generic 2. brand 3. class |
1. lopinavir/ritonavir
2. Kaletra 3. Protease inhibitor |
|
NFV
1. generic 2. brand 3. class 4. Disadvantages |
1. nelfinavir
2. Viracept 3. Protease inhibitor 4. High pill burden, low potency |
|
RTV, r
1. generic 2. brand 3. class 4. special 5. contras 6. sides |
1. ritonavir
2. Norvir 3. Protease inhibitor & Boosting Agent 4. Not an active agent against HIV. Many drug interaction statins, Viagra, Coumadin, methadone, rifampin, amiodarone, fluticasone. Frequent contributor to high triglycerides |
|
SQV
1. generic 2. brand 3. class 4. sides |
1. saquinavir
2. Invirase 3. Protease inhibitor 4. QT prolongation |
|
TPV
1. generic 2. brand 3. class 4. special |
1. tipranavir
2. Aptivus 3. Protease inhibitor 4. High pill burden, low potency |
|
ABC
1. generic 2. brand 3. class 4. special |
1. abacavir
2. Ziagen 3. NRTI 4. only if HLAB5701 negative Risk of MI controversial |
|
ddI
1. generic 2. brand 3. class 4. sides |
1. didanosine
2. Videx, Videx EC 3. NRTI (nucleoside) 4. multiple adverse effects peripheral neuropathy, lipoatrophy/dystrophy, pancreatitis, hepatic steatosis, lactic acidosis |
|
FTC
1. generic 2. brand 3. class 4. interchanged with 5. special |
1. emtricitabine
2. Emtriva 3. NRTI (nucleoside) 4. can be interchanged with lamivudine 5. Active against HBV |
|
3TC
1. generic 2. brand 3. class 4. interchanged with 5. special |
1. lamivudine
2. Epivir 3. NRTI (nucleoside) 4. can be interchanged with emtricitabine 5. Active against HBV |
|
d4T
1. generic 2. brand 3. class 4. sides |
1. stavudine Do Not Use
2. Zerit 3. NRTI (nucleoside) 4. multiple adverse effects peripheral neuropathy, lipoatrophy/dystrophy, pancreatitis, hepatic steatosis, lactic acidosis |
|
TDF
1. generic 2. brand 3. class 4. special |
1. tenofovir
2. Viread 3. NRTI 4. Faconi syndrome |
|
AZT
1. generic 2. brand 3. class 4. sides |
1. zidovudine
2. Retrovir 3. NRTI (nucleoside) 4. Macrocytosis and macrocytic anemia very common Risk of lipoatrophy, lipodystrophy with long term use |
|
FTC + TDF
1. generic 2. brand 3. class 4. known as the 5. Use if 6. special |
1. emtricitabine/tenofovir
2. Truvada 3. NRTI + NtRTI 4. The default option 5. VL > 100,000 6. Two active agents against HBV |
|
ABC + 3TC
1. generic 2. brand 3. class 4. Special |
1. abacavir / lamivudine
2. Epzicom 3. NRTI + NRTI 4. less potent (abacavir compotent only if HLAB5701 negative Risk of MI controversial) |
|
3TC + AZT
1. generic 2. brand 3. class |
1. lamivudine/zidovudine
2. Combivir 3. NRTI + NRTI |
|
EFV
1. generic 2. brand 3. class 4. Special 5. sides |
1. efavirenz
2. Sustiva 3. NNRTI 4. Teratogenicity 5. UNUSUAL DREAMS |
|
NVP
1. generic 2. brand 3. class 4. Sides |
1. nevirapine
2. Viramune 3. NNRTI 4. HEPATOTOXICITY, rash Stevens-Johnson Syndrome. erythema multiforme, toxic epidermal necrolysis |
|
ETV
1. generic 2. brand 3. class 4. sides |
1. etravirine
2. Intelence 3. NNRTI 4. HEPATOMEGALY, A-FIB, Renal failure, Hepatic failure, Stevens-Johnson Syndrome. erythema multiforme, toxic epidermal necrolysis |
|
RPV
1. generic 2. brand 3. class 4. Special 5. sides |
1. rilpivirine
2. Edurant 3. NNRTI 4. Need acidic environment avoid PPI and H2 blocker, antacids Glomerulonephritis, QTc prolongation. |
|
TDF/FTC/EFV
1. generic 2. brand 3. class 4. Built on what other drug |
1. tenofovir/ emtricitabine/efavirenz/
2. Atripla 3. NNRTI + NtRTI + NRTI 4. Truvada PLUS EFV |
|
TDF/FTC/RPV
1. generic 2. brand 3. class 4. Built on what other drug |
1. rilpivirine / tenofovir / emtricitabine
2. Complera 3. NNRTI + NtRTI + NRTI 4. RPV/Truvada |
|
ABC/3TC/AZT
1. generic 2. brand 3. class 4. Special |
1. abacavir /lamivudine/ zidovudine
2. Trizivir 3. NRTI + NRTI + NRTI 4. Only if HLAB5701 negative |
|
TDF
1. generic 2. brand 3. class 4. Special |
1. tenofovir
2. Viread 3. NRTI 4. Caution if GFR < 50 . Screen for Fanconi's syndrome = glycosuria, proteinuria, phos wasting |
|
DLV
1. generic 2. brand 3. class |
1. delavirdine
2. Rescriptor 3. NNRTI |
|
DTG
1. generic 2. brand 3. class |
1. dolutegravir
2. Tivicay 3. Integrase inhibitor |