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32 Cards in this Set

  • Front
  • Back
T20
1. generic
2. brand
3. class of
4. special
1. enfuvirtide
2. Fuzeon
3. entry inhibitor
4. Painful injections only with salvage regimen
MVC
1. generic
2. brand
3. class
4. Special
1. maraviroc
2. Selzentry
3. entry inhibitor
CCR5 receptor antagonist
4. Trofile testing profile needed only use with R5 virus
RAL
1. generic
2. brand
3. class
4. sides
1. raltegravir
2. Isentress
3. raltegravir
4. Stevens-Johnson Syndrome, toxic epidermal necrolysis, renal failure
ATV
1. generic
2. brand
3. class
4. sides
1. atazanavir
2. Reyataz
3. Protease inhibitor
4. Increased risk of nephrolithiasis, Stevens-Johnson Syndrome, toxic epidermal necrolysis, erythema multiforme
FPV
1. generic
2. brand
3. class
4. sides
1. fosamprenavir
2. Lexiva
3. Protease inhibitor
4. High pill burden, low potency
5. Stevens-Johnson syndrome, neutropenia, nephrolithiasis
DRV
1. generic
2. brand
3. class
4. special
4. disadvantage
1. darunavir
2. Prezista
3. Protease inhibitor
4. Highest genetic barrier to resistance
5. Weak sulfa
IDV
1. generic
2. brand
3. class
4. Sides
1. indinavir
2. Crixivan
3. Protease inhibitor
4. Nephrolitihiasis
LPV/RTV (r)
1. generic
2. brand
3. class
1. lopinavir/ritonavir
2. Kaletra
3. Protease inhibitor
NFV
1. generic
2. brand
3. class
4. Disadvantages
1. nelfinavir
2. Viracept
3. Protease inhibitor
4. High pill burden, low potency
RTV, r
1. generic
2. brand
3. class
4. special
5. contras
6. sides
1. ritonavir
2. Norvir
3. Protease inhibitor & Boosting Agent
4. Not an active agent against HIV.
Many drug interaction statins, Viagra, Coumadin, methadone, rifampin, amiodarone, fluticasone.
Frequent contributor to high triglycerides
SQV
1. generic
2. brand
3. class
4. sides
1. saquinavir
2. Invirase
3. Protease inhibitor
4. QT prolongation
TPV
1. generic
2. brand
3. class
4. special
1. tipranavir
2. Aptivus
3. Protease inhibitor
4. High pill burden, low potency
ABC
1. generic
2. brand
3. class
4. special
1. abacavir
2. Ziagen
3. NRTI
4. only if HLAB5701 negative
Risk of MI controversial
ddI
1. generic
2. brand
3. class
4. sides
1. didanosine
2. Videx, Videx EC
3. NRTI (nucleoside)
4. multiple adverse effects
peripheral neuropathy, lipoatrophy/dystrophy, pancreatitis, hepatic steatosis, lactic acidosis
FTC
1. generic
2. brand
3. class
4. interchanged with
5. special
1. emtricitabine
2. Emtriva
3. NRTI (nucleoside)
4. can be interchanged with
lamivudine
5. Active against HBV
3TC
1. generic
2. brand
3. class
4. interchanged with
5. special
1. lamivudine
2. Epivir
3. NRTI (nucleoside)
4. can be interchanged with emtricitabine
5. Active against HBV
d4T
1. generic
2. brand
3. class
4. sides
1. stavudine Do Not Use
2. Zerit
3. NRTI (nucleoside)
4. multiple adverse effects
peripheral neuropathy, lipoatrophy/dystrophy, pancreatitis, hepatic steatosis, lactic acidosis
TDF
1. generic
2. brand
3. class
4. special
1. tenofovir
2. Viread
3. NRTI
4. Faconi syndrome
AZT
1. generic
2. brand
3. class
4. sides
1. zidovudine
2. Retrovir
3. NRTI (nucleoside)
4. Macrocytosis and macrocytic anemia very common
Risk of lipoatrophy, lipodystrophy with long term use
FTC + TDF
1. generic
2. brand
3. class
4. known as the
5. Use if
6. special
1. emtricitabine/tenofovir
2. Truvada
3. NRTI + NtRTI
4. The default option
5. VL > 100,000
6. Two active agents against HBV
ABC + 3TC
1. generic
2. brand
3. class
4. Special
1. abacavir / lamivudine
2. Epzicom
3. NRTI + NRTI
4. less potent
(abacavir compotent
only if HLAB5701 negative
Risk of MI controversial)
3TC + AZT
1. generic
2. brand
3. class
1. lamivudine/zidovudine
2. Combivir
3. NRTI + NRTI
EFV
1. generic
2. brand
3. class
4. Special
5. sides
1. efavirenz
2. Sustiva
3. NNRTI
4. Teratogenicity
5. UNUSUAL DREAMS
NVP
1. generic
2. brand
3. class
4. Sides
1. nevirapine
2. Viramune
3. NNRTI
4. HEPATOTOXICITY, rash
Stevens-Johnson Syndrome. erythema multiforme, toxic epidermal necrolysis
ETV
1. generic
2. brand
3. class
4. sides
1. etravirine
2. Intelence
3. NNRTI
4. HEPATOMEGALY, A-FIB, Renal failure, Hepatic failure, Stevens-Johnson Syndrome. erythema multiforme, toxic epidermal necrolysis
RPV
1. generic
2. brand
3. class
4. Special
5. sides
1. rilpivirine
2. Edurant
3. NNRTI
4. Need acidic environment avoid PPI and H2 blocker, antacids
Glomerulonephritis, QTc prolongation.
TDF/FTC/EFV
1. generic
2. brand
3. class
4. Built on what other drug
1. tenofovir/ emtricitabine/efavirenz/
2. Atripla
3. NNRTI + NtRTI + NRTI
4. Truvada PLUS EFV
TDF/FTC/RPV
1. generic
2. brand
3. class
4. Built on what other drug
1. rilpivirine / tenofovir / emtricitabine
2. Complera
3. NNRTI + NtRTI + NRTI
4. RPV/Truvada
ABC/3TC/AZT
1. generic
2. brand
3. class
4. Special
1. abacavir /lamivudine/ zidovudine
2. Trizivir
3. NRTI + NRTI + NRTI
4. Only if HLAB5701 negative
TDF
1. generic
2. brand
3. class
4. Special
1. tenofovir
2. Viread
3. NRTI
4. Caution if GFR < 50 .
Screen for Fanconi's syndrome = glycosuria, proteinuria, phos wasting
DLV
1. generic
2. brand
3. class
1. delavirdine
2. Rescriptor
3. NNRTI
DTG
1. generic
2. brand
3. class
1. dolutegravir
2. Tivicay
3. Integrase inhibitor