Id Therapeutics Exam 1 Set 3

Front 1

1. superficial infection of skin
2. clinical presentation: localized, purulent infection of the skin; lesions begin as vesicles and become pustules; exposed areas of face and extremities; warm, humid climates; peak incidence in children 2-5
3. spread by person to person contact

Back 1

impetigo

Front 2

what to organisms thought to cause impetigo? (2)

Back 2

1. beta-hemolytic streptococci
2. s. aureus

Front 3

topical antibiotics for impetigo (2)

Back 3

1. mupriocin
2. bacitracin and neomycin (less effective)

Front 4

oral AB for impetigo (5)

Back 4

1. dicloxacillin
2. cephalexin
3. erythromycin
4. clindamycin
5. augmentin

Front 5

treatment for erysipelas (3 classes of AB)

Back 5

1. PCN
2.penicillinase resistant penicillins
3. 1st gen cephalosporins

Front 6

risk factors for developing cellulitis (6)

Back 6

1. obesity
2. edema
3. previous surgery (leg)
4. trauma
5. history of cellulitis
6. current leg ulcer

Front 7

organisms causing cellulitis (7)

Back 7

1. group A strep (s. pyogens)
2. s. aureus including MRSA
3. non group A b-hemolytic strep
4. bacteroides fragilis
5. anaerobic strep
6. aeromonas hydrophilia--fresh water
7. vibrio vulnificus--sea water

Front 8

tx for mild cellulitis infection (4)

Back 8

1. dicloxacillin
2. cephalexin
3. erythromicin
4. clindamycin

Front 9

tx for severe cellulitis infection req hospitalization (4)

Back 9

1. nafcillin
2. cefazolin
3. vancomycin
4. clindamycin

Front 10

CA-MRSA cellulitis tx (4)

Back 10

1. bactrim
2. clindamycin
3. +/- macrolides
4. tetracyclines

Front 11

MRSA cellulitis tx (4)

Back 11

1. vancomycin
2. linezolid
3. daptomycin
4. synercid (quinupristin/dalfopristin)

Front 12

vanco dosing interval for:

age less than 40 and SCr less than 1.4 =

Back 12

q8h

Front 13

vanco dosing interval for:
age 40-65 and SCr less than 1.4

Back 13

q12h

Front 14

vanco dosing interval for:

age greater than 65 OR SCr greater than 1.4 =

Back 14

q24h

Front 15

duration of tx for cellulitis

Back 15

7-14 days

Front 16

likely pathogens of diabetic foot ulcers (5)

Back 16

1. group A strep
2. enterococci
3. S. aureus
4. enterobacteriaceae
5. anaerobes

Front 17

agents used to treat mild foot ulcer infections (6)

Back 17

1. dicloxacillin
2. clindamycin
3. bactrim
4. augmentin
5. levofloxacin

Front 18

agents used to treat moderate foot ulcer infections (13)

Back 18

1. bactrim
2. augmentin
3. levofloxacin
4. cefoxitin
5. ceftriaxone
6. ampicillin/sulbactam
7. linezolid +/- aztreonam
8. daptomycin +/- aztreonam
9. ertapenem
10. cefuroxime (+/- metronidazole)
11. ticarcillin/clavulonate
12. pip/tazo
13. levo or cipro + clindamycin

Front 19

agents used to treat severe foot ulcer infections (4)

Back 19

1. pip/tazo
2. levo or cipro+clindamycin
3. imipenem/cilastatin
4. vanco + ceftazidime (+/- metronidazole)

Front 20

clinical presentation of necrotizing fascitis (7)

Back 20

1. begins like cellulitis (warm, swollen, erythematous, w/o distinctive margins)
2. rapid or slow progression
3. mental status changes
4. lethargy
5. discoloration of skin
6. wooden-hard feeling of the subq tissue
7. severe sx (unexplained pain)

Front 21

organisms that could cause necrotizing fascitis (5)

Back 21

1. s. aureus
2. klebsiella
3. group A strep
4. enterobacteriae
5. anaerobes

CA-MRSA has been reported

Front 22

AB for necrotizing fasciitis w/strep (1)

Back 22

1. penicillin + clindamycin

Front 23

AB for necrotizing fasciitis w/s. aureus (3)

Back 23

1. nefcillin
2. cefazolin
3. clindamycin

Front 24

AB for necrotizing fasciitis w/mixed infection (2)

Back 24

1. amp/sul +clindamycin +ciprofloxacin
2. pip/tazo + clindamycin + ciprofloxacin

Front 25

AB for necrotizing fasciitis w/clostridium infection (2)

Back 25

1. clindamycin
2. penicillin

Front 26

organisms that can cause gas gangrene (4)

Back 26

1. clostridium perfringens
2. c. septicum
3. c. novyi
4. c. histolyticum

Front 27

AB for gas gangrene tx (2)

Back 27

1. penicillin + clindamycin
2. clindamycin + cefoxitin

Front 28

AB for patients with pressure sores that have systemic signs of infection (fever, increased WBC, etc) or have cellulitis, sepsis, osteomyelitis (3 classes)

Back 28

1. b-lactam/b-lactamase inhibitor
2. carbapenem
3. quinolone + clindamycin

Front 29

treatment options for animal bites (8)

Back 29

1. augmentin
2. clindamycin + quinolone (adults)
3. clindamycin + bactrim (children)
4. dicloxacillin + PCN
5. amp/sul
6. pip/tazo
7. cefoxitin
8. carbapenems

Front 30

tx options for human bite with no signs of infection (1)

Back 30

1. augmentin x 5 days

Front 31

tx options for human bite with signs of infection (3)

Back 31

1. amp/sul
2. cefoxitin
3. ertapenem

Front 32

organisms that can cause hematogenous osteomyelitis (7)

Back 32

1. s. aureus
2. e.coli
3. klebsiella
4. salmonella
5. proteus
6. pseudomonas
7. mycobacterium tuberculosis

Front 33

tx for actue osteomyelitis (4)

Back 33

1. cefazolin
2. nafcillin
3. vanco
4. ciprofloxacin

**AB may change based on culture and sensitivity results
**parenteral AB for 4-6 weeks
**s/s for less than 1 month

Front 34

tx for chronic osteomyelitis home IV therapy (3)

Back 34

1. vanco
2. dapto
3. cefazolin

**AB selection based on culture results empiric therapy not recommended

Front 35

organisms that can cause infectious arthritis (5)

Back 35

1. neisseria gonorrhea
2. s. aureus
3. streptococcus
4. e. coli
5. p. aeruginosa

Front 36

tx for infectious arthritis for non-gonnococcal infections (2)

Back 36

1. vanco + ceftriaxone or cefotaxime
2. vanco + cipro or levo

treat for 2-3 weeks

Front 37

tx for infectious arthritis for gonnococcal infections (3)

Back 37

1. ceftriaxone
2. cefotaxime
3. ceftizoxime

**treat for 7 days

Front 38

early onset joint infections caused by (2)

Back 38

1. s. aureus
2. gram - bacilli

Front 39

delayed onset joint infections caused by (1)

Back 39

coagulase negative staphylococci

Front 40

late onset joint infections caused by (2)

Back 40

1. s. aureus
2. coagulase negative staphylococci

if infection follows a UTI it is usually caused by e. coli