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28 Cards in this Set

  • Front
  • Back
Separate strep species based on hemolysis
Alpha (partial hemolysis): S. viridins and S. pneumoniae
Beta (complete hemolysis): Strep groups A-D, F, G (groups A (S. pyogenes), B, and G are virulent)
Gamma (no hemolysis): enterococci
T/F: Streptococcal species are normal skin flora.
FALSE (but can be acquired)
Infections caused by S. pyogenes (Group A Strep)
Puerperal fever/sepsis (post-partum), Scarlet fever, Pharyngitis, erysipelas, cellulitis, impetigo
Drug of choice for Strep
Penicillin (if anaphylactic to PCN, macrolides; if rash, 1st generation cephalosporins)
Who is at highest risk for Group B Strep infections?
Neonates and pregnant women (also adults with immunosuppression)
Listeria in an immunocompetent patient vs. immunocompromised
Immunocompetent: gastroenteritis, fever (generally clears on its own)
Immunocompromised/neonates: septicemia/meningitis
What type of bacteria is often isolated from immunocompromised patients with some sort of indwelling medical device (ex: CSF shunt, catheters)?
Micrococcus
What is the preferred agent for empiric micrococcus treatment?
Vancomycin
What type of infections are commonly caused by Enterobacter?
NOSOCOMIAL bacteremia, pneumonia (esp. early post lung transplant), SSTIs, UTIs (w/ catheter)
Preferred treatment for Enterobacter
4th generation cephalosporin (Cefepime) and carbapenems; or cipro
What are the 3 main complications of pneumococcal PNEUMONIA?
Pericarditis, empyema, lung abscess
Why is vancomycin important in the empiric treatment of meningitis?
In the case of penicillin resistant S. pneumoniae (would be resistant to cephalosporins like Rocephin)
Why does dexamethasone reduce morbidity and mortality in S. pneumococcal meningitis?
Reduces the vigorous immune reaction to the bacteria that is thought to be the cause of the most morbidity and mortality
What is unique about pneumonia caused by R. equi?
Usually only pathogenic in immunocompromised hosts and causes pneumonia with cavitation and abscess formation in the lung (in 50% of cases)
What infections are commonly caused by Serratia?
UTI, LRTI (after mechanical ventilation), bacteremia, endocarditis/osteomyelitis
What is the most common cause of drug fever?
Hypersensitivity
What drug is most commonly associated with neuroleptic malignant syndrome?
Haloperidol
What is the definition of FUO?
1. Temp >38.3 C (101 F)
2. > 3 wks duration of illness
3. Failure to reach dx after 1 week of inpatient investigation
What is the most common cause of FUO?
Infection
What cancers most commonly present as FUOs?
Lymphoma and leukemia
What is the difference between a leukemoid reaction and leukemia?
A leukemoid reaction is a temporary excessive WBC response associated with a cause outside the bone marrow, such as sepsis.
Leukemia is a permanent and progressive leukocytosis.
What are the common characteristics of neuroleptic malignant syndrome?
Rigidity, AMS, autonomic changes and hyperthermia

Also, tachycardia, tachypnea, incontinence, coma, death
Treatment for neuroleptic malignant syndrome
1. Stop neuroleptics
2. Control fever/fluid support
3. Dopamine agonists (bromocriptine, amantidine), beta blockers, benzos, dantrolene (for muscle rigidity)
Most common complications of MRSA bacteremia
Abscesses of abdominal viscera, brain abscesses, meningitis, septic arthritis, osteomyelitis, endocarditis
Infectious causes of pericarditis
1. Viral (coxsackievirus, adenovirus) - effusion may develop, constriction rare
2. Pyogenic (pneumococcus, streptococcus, staph) - effusion, adhesions, and calcification/constriction may occur
3. TB (constriction in up to 50% of cases)
4. Fungal (histo, coccidio, candida, blasto)
What is the most frequent viral cause of pericarditis?
Enterovirus (coxsackievirus)
Cardiac tamponade is more likely to occur from infectious/noninfectious causes of pericarditis.
Noninfectious
Treatment of pericarditis
Bed rest, anti-inflammatories (nonsteroidal or glucocorticoid)