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39 Cards in this Set

  • Front
  • Back
infections affecting epidermis
impetigo
infections affecting dermis and epi
erysipelas
infections affecting subcut tissue, dermis and epi
cellulitis, folliculitis, furuncle, carbuncle
infections affecting fascia
fasciitis
infections affecting muscle
myositis
more suscep to skin infection with...
breaks in the skin, blunt trauma, immunosupp
signs of staph aureus
abscess formation - folliculitis, furunculosis, pustules

local necrosis - from hemolysins, cell surf constituents, cellular debris

toxigenic infec - TSS, scalded skin syndrome

spreading infections - cellulitis
streptococcal infections - most common one, associations
DOES NOT CAUSE ABSCESSES!!!

associated with UResp or GI colonization with group A strep

group a/strep pyogenes is most common - can cause post-strep glomerulonephritis

other beta hemolytic ones aside from group - B and G basically - looks the same as A

B-mainly in immunocomp (elderly, ca, diab, alcoholics)
primary infectiosn of skin
impetigo, erysipelas, cellulitis
things causing ulcers/nodules
anthrax, syphilis, fungal and mycobacterial infections.
when will you see cutaneous manifestations of systemic infections?
toxin-mediated, embolic or systemic
impetigo
staph aureus or strep pyogenes.

vesicles or pustules on honey-yellow crust in children.

benign

post-infec glomerulonephritis is possible.

looks similar to herpes simpelx
txof impetigo
if definitely strep - penicillin

otherwise dicloxacillin or cephalexin - assuming methicillin sensitive
erysipelas
usually group a strep. rarely staph aur or other beta strep (b or g)

sharply demarcated (bc dermal structures confine it), peau d'orange. - raised border and dimpled

systemic toxicity
tx of erysipelas
penicillin (unless it is actually due to staph - but that is rare)
cellulitis
acute, spreading, painful erythema. indistinct borders.

systemic toxicity. - may spread through lymph/blood.

can dev foci of necrosis and bullae.

strep pyogenes (grp A) usually (but staph aureus if due to trauma).

can be due to water exposure adn animal bites too.
predisp factors for cellulitis
trauma is the main one.

obesity, edema, venous insuff, athlete's foot (fissured toe webs)
if dog/cat bite with cellulitis...
consider P. multocida!!! - and cefelexin is not useful for this
dx of cellulitis
pretty hard - clinical appearance is the main thing.

rarely get lucky with cultures, aspiration of inflamed skin, punch biopsy or bulla aspiration.
recurrent cellulitis
strep pyogenes usually.

associated with lymph/venous obstruction.

try chronic penicillin VK
paronychia
painful inf of nail bed/margin

usually staph aureus.

tx - moist heat,drainage, abx oral
strange paronychias
pseudomonas if hands are in water a lot

immunosuppressed can get candida
folliculitis
hair follicle infection --> pustule.

no systemic toxicity.

usually staph aureus

topica antibiotcs
furuncles/carbuncles
abscess originating in hair follicles.

usually staph aureus.

face, axilla, buttock (shaving places)

pretty painful until drainage.
tx o f furuncles
moist heat, draining large lesions, oral abx.
syphilis
priamry - painless indurated ulver. regional lymphadenopathy may be painful though.
sporotrichosis
gardeners/farmers

painless ulcerating pustule.

secondary lesions along lymphatics.
mycobacterium marinum
aquariums and fresh water.
small ulcerating papule with lymphangitic spread.
anthrax
painless papule/ulver with lots of edema and regional lymphadenopathy.

common in world, not in US

has necrotic centers and is painless/doesn't spread.

looks similar to loxocelism spider bite but that is painful and
Eczema
allergic skin disease.
pts with this have staph aureus on their skin (not normal)
lacerations/punctures
usually staph and strept

if puncture through sneaker - pseudomonas aeruginosa
human bites
worse than animal bites bc our mouths have anaerobic bac (so can't tx with cefelexone).

usually from punches to the mouth.

IV tx with ampicillin/sulbactam then amoxicillin/clavulanate (oral) then cefotetan
animal bites
usually polymicrobial

staph aureus, beta hemolytic strep, and pasteruellla (not susc to cefelexone so you need to use penicillin/amoxicillin for this one)

tx - amoxicillin/clavulanate or ampicillin/sulbactam.
decubitus ulcers
from pressure. ("bedsore")

sacral - bowel flora causes it. may penetrate bone (important).

heel - staph or strep
necrotizing fasciitis
necrosis of subcut tissue and overlying skin.

systemic toxicity.

usually group a strept (s. pyogenes) or mixed aerobic/anaer bacteria. NOT STAPH!!

very serious and spreads through fascial layers which have no barriers.

need to do debridement!!
how to differentiate btwn cellulitis and deeper infection
MRI or exploratory.
clues to an anaerobic soft tissue infection
gas production
foul odor
tissue necrosis
rapid spread through tissue planes
gram stain shows mixed organisms.
lyme disease
bull's eye rash

can develop secondary EM (erythema migrans) lesions that are often less distinctive in their appearance.

differs from cellulitis in that erythem amigrans is painless. might have a low grade fever but not systemically ill.
bacterial infections of muscle
pyomyositis - usually staph aureus. e.g. psoas abscess and tropical pyomyositis

streptococcal infection (S. pyogenes) often complicates necrotizing fasciitis

clostridial myonecrosiss (gas gangrene)