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39 Cards in this Set
- Front
- Back
infections affecting epidermis
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impetigo
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infections affecting dermis and epi
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erysipelas
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infections affecting subcut tissue, dermis and epi
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cellulitis, folliculitis, furuncle, carbuncle
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infections affecting fascia
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fasciitis
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infections affecting muscle
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myositis
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more suscep to skin infection with...
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breaks in the skin, blunt trauma, immunosupp
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signs of staph aureus
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abscess formation - folliculitis, furunculosis, pustules
local necrosis - from hemolysins, cell surf constituents, cellular debris toxigenic infec - TSS, scalded skin syndrome spreading infections - cellulitis |
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streptococcal infections - most common one, associations
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DOES NOT CAUSE ABSCESSES!!!
associated with UResp or GI colonization with group A strep group a/strep pyogenes is most common - can cause post-strep glomerulonephritis other beta hemolytic ones aside from group - B and G basically - looks the same as A B-mainly in immunocomp (elderly, ca, diab, alcoholics) |
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primary infectiosn of skin
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impetigo, erysipelas, cellulitis
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things causing ulcers/nodules
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anthrax, syphilis, fungal and mycobacterial infections.
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when will you see cutaneous manifestations of systemic infections?
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toxin-mediated, embolic or systemic
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impetigo
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staph aureus or strep pyogenes.
vesicles or pustules on honey-yellow crust in children. benign post-infec glomerulonephritis is possible. looks similar to herpes simpelx |
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txof impetigo
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if definitely strep - penicillin
otherwise dicloxacillin or cephalexin - assuming methicillin sensitive |
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erysipelas
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usually group a strep. rarely staph aur or other beta strep (b or g)
sharply demarcated (bc dermal structures confine it), peau d'orange. - raised border and dimpled systemic toxicity |
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tx of erysipelas
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penicillin (unless it is actually due to staph - but that is rare)
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cellulitis
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acute, spreading, painful erythema. indistinct borders.
systemic toxicity. - may spread through lymph/blood. can dev foci of necrosis and bullae. strep pyogenes (grp A) usually (but staph aureus if due to trauma). can be due to water exposure adn animal bites too. |
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predisp factors for cellulitis
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trauma is the main one.
obesity, edema, venous insuff, athlete's foot (fissured toe webs) |
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if dog/cat bite with cellulitis...
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consider P. multocida!!! - and cefelexin is not useful for this
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dx of cellulitis
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pretty hard - clinical appearance is the main thing.
rarely get lucky with cultures, aspiration of inflamed skin, punch biopsy or bulla aspiration. |
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recurrent cellulitis
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strep pyogenes usually.
associated with lymph/venous obstruction. try chronic penicillin VK |
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paronychia
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painful inf of nail bed/margin
usually staph aureus. tx - moist heat,drainage, abx oral |
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strange paronychias
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pseudomonas if hands are in water a lot
immunosuppressed can get candida |
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folliculitis
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hair follicle infection --> pustule.
no systemic toxicity. usually staph aureus topica antibiotcs |
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furuncles/carbuncles
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abscess originating in hair follicles.
usually staph aureus. face, axilla, buttock (shaving places) pretty painful until drainage. |
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tx o f furuncles
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moist heat, draining large lesions, oral abx.
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syphilis
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priamry - painless indurated ulver. regional lymphadenopathy may be painful though.
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sporotrichosis
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gardeners/farmers
painless ulcerating pustule. secondary lesions along lymphatics. |
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mycobacterium marinum
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aquariums and fresh water.
small ulcerating papule with lymphangitic spread. |
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anthrax
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painless papule/ulver with lots of edema and regional lymphadenopathy.
common in world, not in US has necrotic centers and is painless/doesn't spread. looks similar to loxocelism spider bite but that is painful and |
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Eczema
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allergic skin disease.
pts with this have staph aureus on their skin (not normal) |
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lacerations/punctures
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usually staph and strept
if puncture through sneaker - pseudomonas aeruginosa |
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human bites
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worse than animal bites bc our mouths have anaerobic bac (so can't tx with cefelexone).
usually from punches to the mouth. IV tx with ampicillin/sulbactam then amoxicillin/clavulanate (oral) then cefotetan |
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animal bites
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usually polymicrobial
staph aureus, beta hemolytic strep, and pasteruellla (not susc to cefelexone so you need to use penicillin/amoxicillin for this one) tx - amoxicillin/clavulanate or ampicillin/sulbactam. |
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decubitus ulcers
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from pressure. ("bedsore")
sacral - bowel flora causes it. may penetrate bone (important). heel - staph or strep |
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necrotizing fasciitis
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necrosis of subcut tissue and overlying skin.
systemic toxicity. usually group a strept (s. pyogenes) or mixed aerobic/anaer bacteria. NOT STAPH!! very serious and spreads through fascial layers which have no barriers. need to do debridement!! |
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how to differentiate btwn cellulitis and deeper infection
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MRI or exploratory.
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clues to an anaerobic soft tissue infection
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gas production
foul odor tissue necrosis rapid spread through tissue planes gram stain shows mixed organisms. |
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lyme disease
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bull's eye rash
can develop secondary EM (erythema migrans) lesions that are often less distinctive in their appearance. differs from cellulitis in that erythem amigrans is painless. might have a low grade fever but not systemically ill. |
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bacterial infections of muscle
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pyomyositis - usually staph aureus. e.g. psoas abscess and tropical pyomyositis
streptococcal infection (S. pyogenes) often complicates necrotizing fasciitis clostridial myonecrosiss (gas gangrene) |