Icp Short Meti-Man Drug List

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Routes of Admin

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Enteral (via GI / alimentary Tract--Oral; Sublingual, Rectal) or Parenteral (NOT via GI tract--Inhalation; IV; IM; SC; Transdermal, Topical)

Routes of Admin

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Anxiolytics / Premed / Morning Cocktail

Back 2

can give w / narcotic like Fentanyl, but lower dose or will see resp depression

Anxiolytics / Premed / Morning Cocktail
Group 1

Front 3

Anxiolytics

Back 3

a drug that relieves anxiety.

An anxiolytic (antipanic or antianxiety agent) is a drug prescribed for the treatment of symptoms of anxiety.

Some anxiolytics have been shown to be useful in the treatment of anxiety disorders, as have antidepressants such as the class of selective serotonin reuptake inhibitors (SSRIs).

Front 4

Midazolam
Drug
(trade name)

Back 4

(Versed)

Anxiolytics / Premed / Morning Cocktail
Group 1

Front 5

Midazolam
[ Supplied ]

Back 5

1mg / mL

Anxiolytics / Premed / Morning Cocktail
Group 1

Front 6

Midazolam
Dosing--Stever

Back 6

1-2.5mg

Anxiolytics / Premed / Morning Cocktail
Group 1

Front 7

Induction Drugs

Back 7

very lipid soluble, fast on, fast off, short duration (3-5m), Note Propofol / etomidate burn on injection, ketamine has Analgesic effects, and thiopental has a high pH…watch out for crystallization of drug if added w / acidic drug…instead, push thiopental, flush through into body w / IV fluid, then do acidic drug

Induction Drugs
Group 2

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Propofol
Drug
(trade name)

Back 8

(Diprivan)

Induction Drugs
Group 2

Front 9

Propofol
[ Supplied ]

Back 9

10mg / mL

Induction Drugs
Group 2

Front 10

Sodium Thiopental
Drug
(trade name)

Back 10

Sodium Thiopental
(aka: Sodium Pentothal)

Induction Drugs
Group 2

Front 11

Sodium Thiopental
[ Supplied ]

Back 11

2.5%

Induction Drugs
Group 2

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Propofol
Dosing--Stever

Back 12

1.5-2.5mg / kg Ind; 25-100mcg / kg / min Inf.

Induction Drugs
Group 2

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Barbiturate

Back 13

A drug with sedative and hypnotic properties belonging to a group of derivatives of barbituric acid

Front 14

Local Anesthetics

Back 14

Transient loss of sensory, motor, and autonomic function in a discrete portion of the body; reversible conduction of blockade of impulses along central and peripheral nerve pathways; Divided into Amides and Esters; Amides ( I b4 caine) metabolized by liver & Esters (no i b4 caine) metabolized in plasma via plasma cholinesterases, also will cause allergic Rxn in ppl allergic to PABA in sunscreen. Note that Vasoconstrictors (i.e. Epinephrine) increase duration of action of local anesthetic by limiting systemic absorption and maintaining the drug [c] at the nerve. It also decreases possibility of systemic toxicity and has little effect on onset (use 5mcg / ml or 1:200,000 Epi w / local anesthetic); Symptoms of Toxicity: Circumoral numbness (lips), Tinnitus (ringing in ears), taste pennies, lightheadedness, visual disturbances, muscular twitching, unconsciousness, convulsions, respiratory depression, cardiovascular collapse (described w / increasing levels of toxicity);PVC=premature ventricular contraction; Infiltration=using lidocaine to numb area b4 giving IV / creating wheal under skin; use nebulizer to numb airway for awake intubation; use at induction to attenuate burning on injection of induction drugs; IV regional anesthesia (IVRA) = Bier Block; Peripheral Nerve Block (PNB) = ankle or femural block;
.


Local Anesthetics
Group 11

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Lidocaine
Drug
(trade name)

Back 15

Lidocaine

Local Anesthetics
Group 11

Front 16

Lidocaine
[ Supplied ]

Back 16

0.5-5%

Local Anesthetics
Group 11

Front 17

Lidocaine
Dosing--Stever

Back 17

Topical (4%); Infiltration (0.5-1%); IVRA (0.25-0.5%); PNB (1-1.5%); Epidural (1.5-2%); Spinal (1.5-5%)

Local Anesthetics
Group 11

Front 18

NMB Reversal Drugs

Back 18

The Wake Up; Induction drugs long gone, turned gas off so that is gone too, need to get rid of NMBs; Anticholinesterase Drugs prevent the hydrolysis of Ach, and an increase [Ach] @ NMJ competes with ND NMBDs; clinical uses--reversal of Non-depol NMBDs; Mech. of action--enzyme inhibition, pre-synaptic effects, NMJ effects; get this increase [Ach] everywhere though, so get the BLUDS effect--attenuate by using in combination w / Anticholinergic drugs; BLUDS= bradycardia / bronchospasm, lacrimation, urination, defication, salivation; Anticholinergic Drugs used clinically most often as pre-op med, for treatment of bradycardia, for NDNMB reversal and less frequently for bronchodialation, smooth muscle relaxant, antagonist of gastric acid secretion, & to prevent N / V; work by blocking muscarinic Ach receptors activated by parasymp. NS, careful though....will cause dialation of pupils (worsens Glaucoma) and will cross placenta in pregnant woman (Cautions=Glaucoma / Parturients). (Parturient=pregnant woman)

NMB Reversal Drugs
Group 9

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Atropine
Drug
(trade name)

Back 19

Atropine

NMB Reversal Drugs
Group 9

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Atropine
[ Supplied ]

Back 20

0.4, 0.5, 1mg / ml

NMB Reversal Drugs
Group 9

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Atropine
Dosing--card

Back 21

1.0mg vagolytic dose; 0.01mg / kg NMB reversal

NMB Reversal Drugs
Group 9

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Neuromuscular Blocking Drugs

Back 22

Paralysis / Muscle Relaxation; Facilitate tracheal intubation, improve surgical working conditions, good for mechanical ventilation of lungs, treat laryngospasm; Classified / chosen according or whether Depolarizing (mimics ACh, binds receptor @ muscle and activates receptor) or Non-depolarizing (binds @ receptor and blocks ACh), duration of action (whether long, intermediate or short acting; duration also affected by liver / kidney disease so keep that in mind), speed of onset, side effects, & pathophysiology; Act by interupting transmission of nerve impulses at NMJ of muscles; review in ppt adverse effects of SUX); Note: Int= Intubation Dose, Inf= Infusion

Neuromuscular Blocking Drugs
Group 3

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Cisatracurium
Drug
(trade name)

Back 23

(Nimbex)

Neuromuscular Blocking Drugs
Group 3

Front 24

Cisatracurium
[ Supplied ]

Back 24

20mg vial (2mg / ml)

Neuromuscular Blocking Drugs
Group 3

Front 25

Benzyl isoquinolinium

Back 25

Isoquinolines find many applications, including (but not limited to): anesthetics; dimethisoquin is one example.
vasodilators, a well-known example, papaverine.

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Cisatracurium
Dosing--Stever

Back 26

Int same, Inf 1-2mcg / kg / min

Neuromuscular Blocking Drugs
Group 3

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Pancuronium
Drug
(trade name)

Back 27

(Pavulon)

Neuromuscular Blocking Drugs
Group 3

Front 28

Pancuronium
[ Supplied ]

Back 28

1mg / mL

Neuromuscular Blocking Drugs
Group 3

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Pancuronium
Dosing--Stever

Back 29

Int same, Mt 0.01mg / kg

Neuromuscular Blocking Drugs
Group 3

Front 30

Rocuronium
Drug
(trade name)

Back 30

(Zemuron)

Neuromuscular Blocking Drugs
Group 3

Front 31

Rocuronium
[ Supplied ]

Back 31

10mg / ml

Neuromuscular Blocking Drugs
Group 3

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Rocuronium
Dosing--Stever

Back 32

Int same (RSI dose), Maint 0.1mg / kg, Infusion 5-12 mcg / kg / min

Neuromuscular Blocking Drugs
Group 3

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Aminosteroid

Back 33

Aminosteroids are a group of drugs with a similar structure based on a steroid nucleus.
Examples are the muscle relaxants rocuronium, vecuronium and pancuronium.

Front 34

Succinylcholine
Drug
(trade name)

Back 34

Succinylcholine (Anectine)

Neuromuscular Blocking Drugs
Group 3

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Succinylcholine
[ Supplied ]

Back 35

20mg / ml

Neuromuscular Blocking Drugs
Group 3

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Succinylcholine
Dosing--Stever

Back 36

Int same; Laryngospasm 0.1mg / kg IV

Neuromuscular Blocking Drugs
Group 3

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Vecuronium
Drug
(trade name)

Back 37

(Norcuron)

Neuromuscular Blocking Drugs
Group 3

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Vecuronium
[ Supplied ]

Back 38

10mg powder vial, reconst. to 1mg / ml w / 10cc sdH2O

Neuromuscular Blocking Drugs
Group 3

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Vecuronium
Dosing--Stever

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Int same, Inf 1-2mcg / kg / min, Maint 0.01mg / kg

Neuromuscular Blocking Drugs
Group 3

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Sympathomimetics

Back 40

Uppers; ↑BP; pt's "tubes" not full b / c haven't eaten, dehydrated, etc., if you vasoconstrict you can increase volume compared to size of tube, inserting ETT raises BP b / c it is a strong stimulus, then BP may drop until next stimulus--surgical incision, so may need to use these until then to keep BP at desired / reasonable rate; Divided into Catecholamines & Synthetic Noncatecholamines; work through activation of α (vasculature--vasocontriction), β1 (heart--↑HR) and / or β2 (lungs--brachial relaxation) receptors--remember this w / mnemonic 1 Heart, 2 lungs for beta receptors

Sympathomimetics
Group 7

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Sympathomimetics

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Describes a drug that stimulates the sympathetic nervous system or produces physiological effects similar to it

Front 42

Ephedrine
Drug
(trade name)

Back 42

Ephedrine

Sympathomimetics
Vasoactive Drugs
Group 7

Front 43

Ephedrine
[ Supplied ]

Back 43

5mg / ml(from 25 or 50 mg / 1mL vial)

Sympathomimetics
Vasoactive Drugs
Group 7

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Ephedrine
Dosing--Stever

Back 44

5-20 mg

Sympathomimetics
Vasoactive Drugs
Group 7

Front 45

Phenylephrine
Drug
(trade name)

Back 45

Phenylephrine

Sympathomimetics
Vasoactive Drugs
Group 7

Front 46

Phenylephrine
[ Supplied ]

Back 46

100mcg / mL

Sympathomimetics
Vasoactive Drugs
Group 7

Front 47

Phenylephrine
Dosing--Stever

Back 47

Bolus 50-100mcg, Inf 0.25-1 mcg / kg / min

Sympathomimetics
Vasoactive Drugs
Group 7

Front 48

Opioids / Narcotics

Back 48

Pain Relief; choose based on potency, onset / duration time and method of metabolization (keep byproducts and their toxicity in mind).

Opioids / Narcotics
Group 4

Front 49

Fentanyl
Drug
(trade name)

Back 49

Fentanyl

Opioids / Narcotics
Group 4

Front 50

Fentanyl
[ Supplied ]

Back 50

50mcg / ml

Opioids / Narcotics
Group 4

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Morphine
Dosing--Stever

Back 51

Intraop 0.1-1mg / kg IV; Postop 0.03-0.15mg / kg IV

Opioids / Narcotics
Group 4

Front 52

Synthetic Opioid

Back 52

An Opiod made artificially by chemical synthesis, especially so as to resemble a natural product