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33 Cards in this Set
- Front
- Back
3 prerequisites for performing a kidney biopsy
|
normal bleeding time
pt has 2 kidneys no UTI |
|
2 kinds of nephrotic syndrome
|
primary
secondary |
|
4 kinds of primary NS
|
MCD
FSGS membranous nephropathy MPGN |
|
3 kinds of secondary NS
|
amyloidosis
SLE diabetic GS |
|
___ is most common NS in kids
___ is most common NS in adults |
MCD
membranous nephropathy |
|
NS patients are hyper___. for this reason it's important not to give them ___. ___ are the main hazard of NS.
|
coagulable
diuretics thromboembolic complications |
|
NS ____ should be treated with statins
|
hypercholesterolemia
|
|
3 common thromboembolic events in NS
|
renal vein thrombosis
PE DVT |
|
if you need to give diuretics to NS pt, you must also give ___. this is restricted to ____ cases because of ___.
|
albumin
morbid edema high cost |
|
patients with serum albumin below ___ and urinary protein above ___ require ___
|
2 g
10 g prophylactic anticoagulation |
|
infections are elevated in NS due to loss of ___ (2)
|
IgG
factor B (alternative complement) |
|
malignancies such as ___ account for ___% of idiopathic NS in adults
|
lymphoma
10 |
|
the only time MCD causes renal failure is when ____ causes ____.
|
hypovolemia
ARF |
|
membranous nephropathy ICs contain ___ (2)
|
IgG
complement |
|
6 main causes of membranous nephropathy
|
idiopathic
SLE lung cancer NHL HBV NSAIDs |
|
because of ___, HTN is present in membranous nephropathy.
|
GBM fibrosis
|
|
___% of kids and ___% of adults with membranous nephropathy progress to end-stage renal disease.
|
10
20 |
|
tx of MN is ___ alternating with either ___ or ___
|
methylprednisolone
chlorambucil CTX |
|
2 other MN drugs
|
cyclosporin
azathioprine |
|
in FSGS, circulating ICs can be removed by ___
|
plasmapheresis
|
|
___ is a drug which can cause FSGS. it is part of the ___ family and is used for ____
|
pamidronate
bisphosphonate osteoporosis |
|
FSGS presents clinically with ___ (3)
|
rapidly developing edema
heavy proteinuria hematuria |
|
HIV patients and ___ get ___ FSGS
|
African americans
collapsing |
|
hyperfiltration stage of DM nephropathy happens ___ years after diagnosis and has ___ GFR, ___ BP, and ___ albuminuria
|
0
high normal no |
|
latency stage of DM nephropathy happens ___ years after diagnosis and has ___ GFR, ___ BP, and ___ albuminuria
|
5-15
high normal high normal no |
|
microalbuminuria stage of DM nephropathy happens ___ years after diagnosis and has ___ GFR, ___ BP, and ___ albuminuria
|
10-15
normal high <300 mg/day |
|
macroalbuminuria stage of DM nephropathy happens ___ years after diagnosis and has ___ GFR, ___ BP, and ___ albuminuria
|
10-15
low high > 300 mg/day |
|
renal failure stage of DM nephropathy happens ___ years after diagnosis and has ___ GFR, ___ BP, and ___ albuminuria
|
15-30
very low high massive |
|
the irreversible stages of DM nephropathy are ___ (2)
|
macroalbuminuria
renal failure |
|
microalbuminuria can be monitered via the ___ ratio. the normal ratio is ___
|
albumin/creatinine
<0.02 |
|
2 kinds of amyloid implicated in kidney disease
|
AA
AL |
|
AA accumulation is caused by ___. the protein is ___. this kind of amyloidosis is called ___. 2 causes are ___
|
chronic inflammation
serum amyloid A (acute phase) secondary RA FMF |
|
AL accumulation is caused by ___. the protein is ___. this kind of amyloidosis is called ___. one cause is ___
|
plasma cell dyscrasia
Ig light chain lambda primary multiple myeloma |