Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
18 Cards in this Set
- Front
- Back
|
in cirrhosis, NO is ___ in liver and ___ peripherally
|
low
high |
|
|
elevated systemic ___ causes elevated ____ (3)
|
RAA activation
sympathetic tone ADH |
|
|
endothelial dysfunction in cirrhosis is caused by ___ (3)
|
inflammation
ROS alcohol |
|
|
the only part of the body outside liver which is not vasodilated in cirrhosis
|
kidneys
|
|
|
water is retained/lost in cirrhosis
|
retained
|
|
|
overflow hypothesis of water retention says it's caused by ___
|
renal water reabsorption
|
|
|
underflow hypothesis of water retention says it's caused by ___ which causes ___
|
portal hypertension
loss of volume to ascites |
|
|
3 causes of increased infection in cirrhosis
|
decreased complement
vasodilation causes easier penetration reduced hepatic detoxification because of portal HTN |
|
|
post surgical is more/less painful than primary peritonitis
|
more
|
|
|
3 most common causes of spontaneous bacterial peritonitis
|
E. coli
S. pneumoniae Klebsiella |
|
|
main part of tx for cirrhotic ascites
|
Na+ restriction
|
|
|
Na+ restriction for ascites management
|
2g i.e. 88 mmol/day
|
|
|
if diet alone doesn't fix ascites, use ___ or ___
|
paracentesis
diuretics |
|
|
it's important to give ___ after paracentesis
|
albumin
|
|
|
5 criteria of hepatorenal syndrome (HRS)
|
low GFR/creatinine>1.5mg%
absence of shock proteinuria < 500 mg/day no obstructive uropathy no improvement after diuretic withdrawal |
|
|
2 tx for HRS
|
ornipressin, an ADH analogue
TIPS: transjugular intrahepatic portosystemic shunt |
|
|
3 tx for hepatic encephalopathy
|
removal of precipitating factors
lactulose antibiotics |
|
|
___ is prophylactic tx for portal HTN
|
beta blockers
|
