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109 Cards in this Set

  • Front
  • Back

CELL BIOLOGY


What does cell theory state?

* All living things are made from cells


* Cells are the smallest unite of life


* All cells come from pre-existing cells

CELL BIOLOGY


What are exceptions to cell theory?

Skeletal muscles - made up of long muscle fibers with many nuclei


Giant algae - despite being very big, are unicellular


Aseptate fungi - not divided into cells, instead consist of multiple nuclei

CELL BIOLOGY


What are the requirements/functions of life for something be considered alive?

Metabolism


Reproduction


Sensory/response to stimuli


Homeostasis


Excretion


Nutrition/exchange of gas & materials


Growth

CELL BIOLOGY

What are stem cells?

Cells that can differentiate into a limited range of cells

CELL BIOLOGY


Where are stem cells found?

* bone marrow


* skin


* liver

CELL BIOLOGY


What is the formula to calculate magnification of a microscope image?

Magnification = Size of image / size of organism

CELL BIOLOGY


What is the formula to calculate real size of organism in a microscope image?

Size of organism = size of image/magnification

CELL BIOLOGY


How much is 1 cm in μm?

1 cm = 10,000 μm

CELL BIOLOGY


How much is 1 mm in μm?

1 mm = 1,000 μm

CELL BIOLOGY


What are the properties of a Totipotent cell? (with example)

Can differentiate into any cell, including a placenta


e.g. zygotes

CELL BIOLOGY


What are the properties of a pluripotent cell? (with example)

can differentiate into any cell making up the body


e.g. embryonic stem cells

CELL BIOLOGY


What are the properties of a multipotent cell? (with example)

Can differentiate into a number of similar cell types


e.g. adult stem cells

CELL BIOLOGY


What are the properties of a unipotent cell? (with example)

Cant differentiate, but can replicate itself


e.g. regular body cells

CELL BIOLOGY


What are the characteristics and structure of a prokaryotic cell? (at least 8)

* no nucleus


* not compartmentalized


* have plasmids


* (usually) unicellular


* small ribosomes


* circular DNA


* singular chromosome


* transcription and translation occur simultaneously


* (usually) haploid

CELL BIOLOGY


What are the characteristics and structure of a eukaryotic cell? (at least 8)

* nucleus


* compartmentalized w/ variety of organelles


* (usually) multicellular


* large ribosomes


* multiple chromosomes


* linear DNA


* DNA wrapped in histones


* (usually) diploid


* transcription occurs in the nucleus, translation in the cytoplasm

CELL BIOLOGY


What is binary fission?

The process of which prokaryotic cells divide.

CELL BIOLOGY


What are the universal organelles found in both eukaryotic and prokaryotic cells? (list and briefly describe 2)

Ribosome - site of polypeptide synthesis/translate RNA into amino-acids


Plasma membrane - phospholipid bilayer to act as a semi-permeable and selective barrier

CELL BIOLOGY


What organelles are found only in animal cells (list and briefly describe 5)

Nucleus - stores genetic material


Endoplasmic reticulum - can be bare (smooth ER) or have ribosomes (rough ER). transports materials between organelles


Golgi apparatus - sorts, stores, modifies and exports secretory products


Mitochondria - the powerhouse of the cell ( ͡° ͜ʖ ͡°)


Centrosome - creates spindle fibers which help cell division



CELL BIOLOGY


What organelles are found only in plant cells? (list and briefly describe 3)

Chloroplast - contains stacks of thylakoids, site of photosynthesis


Vacuole - fluid filled cavity, helps maintain structure


Cell wall - rigid and made from cellulose

CELL BIOLOGY


Describe the structure of the phospholipid bilayer

Polar/hydrophilic heads on the outside


two non-polar/hydrophobic tails on the inside

CELL BIOLOGY


What is the role of cholesterol in animal cell membranes?

Reduces the fluidity of the membrane and less permable

MOLECULAR BIOLOGY


Define passive transport



natural movement of particles from high to low concentration (no energy required)

MOLECULAR BIOLOGY


Define facilitated difusion

movement of particles through membrane proteins/channels

MOLECULAR BIOLOGY


Define active transport

Movement of particles against its concentration gradient, required energy

MOLECULAR BIOLOGY


What happens when a cell is hypertonic?

Particles/water leaves the cell causing it to shrivel

MOLECULAR BIOLOGY


What happens when a cell is hypotonic?

Particles/water enter the cell causing it to swell

CELL DIVISION


Briefly describe the 4 main stages of the cell cycle?

1. G1 - Growth and normal metabolism


2. S phase - DNA is replicated


3. G2 - Growth and preperation for division


4. Mitosis - Cell division

CELL DIVISION


What stages are part of Interphase during the cell cycle?

G1, S phase, G2

CELL DIVISION


What happens during interphase in mitosis?

* DNA replicates (still uncondensed)


* Organelles replicates


* Cell is enlarged

CELL DIVISION


What happens during prophase in mitosis?

* DNA supercoils into chromosomes


* Chromosome clone into sister chromatids


* Nucleus dissolve


* Centromere move to opposite poles and form microtubule spindle fibers.

CELL DIVISION


What happens during metaphase in mitosis?

* Microtuble spindles from the centromeres connect to the centrosome of each chromosome


* Spindles contract and shorten, aligning the chromosomes along the center/equator of the cell

CELL DIVISION


What happens during anaphase in mitosis?

* spindles contract and pull sister chromatids apart into separate poles

CELL DIVISION


What happens during telophase in mitosis?

* two nuclei form


* chromosomes decondense


*cytokinesis splits the cell into two

CELL DIVISION  
What stage of mitosis is this?

CELL DIVISION


What stage of mitosis is this?

Interphase

CELL DIVISION
What stage of mitosis is this?

CELL DIVISION


What stage of mitosis is this?

Prophase
CELL DIVISION
What stage of mitosis is this?

CELL DIVISION


What stage of mitosis is this?

Metaphase

CELL DIVISION
What stage of mitosis is this?

CELL DIVISION


What stage of mitosis is this?

Anaphase

CELL DIVISION
What stage of mitosis is this?

CELL DIVISION


What stage of mitosis is this?

Telophase

CELL DIVISION


What are the 5 stages of mitosis? (in order)

1. Interphase


2. Prophase


3. Metaphase


4. Anaphase


5. Telophase

CELL DIVISION


Describe the role of cyclins in the cell cycle

Cyclins are protein which regulate the progression of the cell cycle by forming a complex with CDK.


Cyclin-CDK complex activates proteins which triggers cell cycle events.

CANCER DEVELOPMENT


Define oncogenesis

The formation of tumor cells

CANCER DEVELOPMENT


Define oncogene

A gene controlling the cell cycle

CANCER DEVELOPMENT


What is the difference between a primary and secondary tumor?

Primary tumor - often harmless, don't grow as rapidly and don't spread


Secondary tumor - becomes dangerous when it detaches and migrates elsewhere in the body and develop a new tumor.

CANCER DEVELOPMENT


Define metastasis

When a tumor migrates to a new locations and starts a new tumor

MOLECULAR BIOLOGY


What does the theory of vitalism believe in?

That life are dependent on a force or principle distinct from purely chemical or physical forces.




That only living organisms can make organic matter

MOLECULAR BIOLOGY


How was the theory of vitalism falsified?

When Frederick Woehler artificially created urea in a lab

MOLECULAR BIOLOGY


Describe hydrolysis

The breakdown of a polymer by breaking the oxygen bond between them and replacing it hydrogen and oxygen from water

MOLECULAR BIOLOGY


Describe condensation

The creation of an oxygen bond between two monomers, making them a polymer. Water is created from this process

MOLECULAR BIOLOGY


What is the difference between anabolism and catabolism?

Anabolism is the building of complex molecules from simpler monomers using energy.


Catabolism is the breakdown of complex molecules into simpler monomers, releasing energy.

MOLECULAR BIOLOGY


Why is water a good coolant? (e.g. in sweat)

Water molecules evaporate when the weak hydrogen bonds between them are broken using energy from heat (for example, body heat).


Therefore, evaporating water can easily dissipate heat.

MOLECULAR BIOLOGY


What are the benefits of using starch and glycogen to store energy?

Both are insoluble in water, so storing large amounts of them dont cause osmotic issues in the cell.

Both are branched, making it easy to load/unload monomers from it.

MOLECULAR BIOLOGY


Is this ribose or deoxoribose?

MOLECULAR BIOLOGY


Is this ribose or deoxoribose?

Ribose
MOLECULAR BIOLOGY
is this ribose or deoxoribose?

MOLECULAR BIOLOGY


is this ribose or deoxoribose?

Deoxoribose

MOLECULAR BIOLOGY


Is this α glucose or 

β

 glucose?

MOLECULAR BIOLOGY


Is this α glucose or β glucose?

β glucose

MOLECULAR BIOLOGY
Is this α glucose or β glucose?  

MOLECULAR BIOLOGY


Is this α glucose or β glucose?

α glucose

MOLECULAR BIOLOGY


Whats the difference in structure and use between α glucose and β glucose?

α glucose makes starch, form helix shaped branches and chains that are ideal for sugar storage, as sugars can easily be added and removed from the chain


β glucose makes cellulose, form strongly bonded straight chains/microfibrills. used as a rigid base for plant cell structure

MOLECULAR BIOLOGY


What are the pros and cons of using sugar vs lipids as energy storage?

Sugars:


* release less energy


* can be broken down much faster (ideal for short term storage)


Lipids:


* release more energy


* take longer to breakdown (ideal for longterm storage)


* can be used as heat insulators and shock-absorbers (protect organs)

MOLECULAR BIOLOGY


What is the difference between cis unsaturated fatty-acid and trans unsaturated?

Cis - hydrogen are bonded on the same side of the double bond, bended in shape.


Trans - hydrogen are bonded on opposite sides of the double bond, straight in shape, associated with heart disease.

MOLECULAR BIOLOGY


Define denaturation

the irreversible change in shape of a protein due to extreme heat/pH

MOLECULAR BIOLOGY (Proteins)


Describe the function of rubisco

An Enzyme which catalyses the photosynthesis/Calvin cycle reaction that fixes CO2 to RuBP

MOLECULAR BIOLOGY (Proteins)


Describe the function of Insulin

A Hormone that binds to insulin receptors on cells, causing them to absorb more sugar and lower overall blood pressure

MOLECULAR BIOLOGY (Proteins)


Describe the function of immunoglobulin

A antibody that binds to antigens on pathogens

MOLECULAR BIOLOGY (Proteins)


Describe the function of rhodospin

A pigment that allow the rod cells of the retina to detect and be sensitive to light

MOLECULAR BIOLOGY (Proteins)


Describe the function of collagen

Has a rope-like structure that helps maintain structure.

MOLECULAR BIOLOGY (Proteins)


Describe the function of spidersilk

Has a very strong yet flexible structure. becomes stronger when stretched

MOLECULAR BIOLOGY


Which fatty acid is this?

MOLECULAR BIOLOGY


Which fatty acid is this?

Unsaturated trans fatty acid

MOLECULAR BIOLOGY
Which fatty acid is this?

MOLECULAR BIOLOGY


Which fatty acid is this?

Unsaturated cis fatty acid

MOLECULAR BIOLOGY
Which fatty acid is this?

MOLECULAR BIOLOGY


Which fatty acid is this?

Saturated fatty acid

HUMAN PHYSIOLOGY (Blood system)


What is the difference in role between a vein and artery?



Vein - delivers oxygenatedblood to the heart from the organs


Artery - delivers oxygenated blood at high pressure from the heart to organs

HUMAN PHYSIOLOGY (Blood system)


what is the function of the aorta?

Delivers blood from the heart to all other organs except the lungs

HUMAN PHYSIOLOGY (Blood system)


What is the function of the pulmonary artery?

Delivers blood from the heart to the lungs

HUMAN PHYSIOLOGY (Blood system)


What is the role of the vena cava?

Delivers deoxygenated blood from the organs to the heart

HUMAN PHYSIOLOGY (Blood system)


To which heart chamber does the vena cava first deliver blood to?

To the right atrium

HUMAN PHYSIOLOGY (Blood system)


To which chamber does blood from the right atrium flow to?

The right ventricle

HUMAN PHYSIOLOGY (Blood system)


Through which valve does blood from the right ventricle flow into the right ventricle?

The tricuspid valve

HUMAN PHYSIOLOGY (Blood system)


Where does blood from the right ventricle flow into?

The pulmonary artery

HUMAN PHYSIOLOGY (Blood system)


Through which valve does blood from the right ventricle flow into the pulmonary artery?

The pulmonary valve

HUMAN PHYSIOLOGY (Blood system)

Into which heart chamber does blood from the pulmonary veins flow into?

The left atrium

HUMAN PHYSIOLOGY (Blood system)


Where does blood from the left atrium flow into?

The Left ventricle

HUMAN PHYSIOLOGY (Blood system)


What the is term for the valves between the ventricles and arteries?

Semilunar valves

HUMAN PHYSIOLOGY (Blood system)


What the is term for the valves between the atrium and ventricle?

Atrioventricular valves

HUMAN PHYSIOLOGY (Blood system)


Define systolic presure

The maximum blood pressure level in the arteries

HUMAN PHYSIOLOGY (Blood system)


Define diastolic presure

The minimum blood pressure level in the arteries

HUMAN PHYSIOLOGY (Blood system)


Define vasoconstriction

The narrowing of artery walls to increase blood presure

HUMAN PHYSIOLOGY (Blood system)


Define vasoconstriction

The expanding of artery walls to decrease blood presure

HUMAN PHYSIOLOGY (Blood system)


Name 6 physical characteristics of veins

*much larger than 10 μm


*thin wall


*wide lumen


* consists of 3 layers


* contains few elastic fibers


* contains valves

HUMAN PHYSIOLOGY (Blood system)


Name 5 physical characteristics of arteries

*Larger than 10 μm


* thick wall


*narrow lumen


* consists of 3 layers (sometimes more)


* muscle and elastic fibers in cell wall

HUMAN PHYSIOLOGY (Blood system)


Name 4 physical charateristics of cappilaries

*around 10μm


* extremely thin wall


* consists of one thin layer


*semi-permeable cell walls

HUMAN PHYSIOLOGY (Blood system)


What is the role of the sinoatrial node?

To act as the pacemaker controlling the heartbeat rate

HUMAN PHYSIOLOGY (Blood system)


What is the role of the sympathetic nerve?

To activate noradrenaline to increase heartrate

HUMAN PHYSIOLOGY (Blood system)


What is the role of the parasympathetic nerve?

To activate acetycholine to decrease heartrate

HUMAN PHYSIOLOGY (Blood system)

HUMAN PHYSIOLOGY (Blood system)

HUMAN PHYSIOLOGY (Blood system)

HUMAN PHYSIOLOGY (Blood system)

SEXUAL REPRODUCTION


Define oogenesis

The production of eggs within the ovaries

SEXUAL REPRODUCTION


Define spermatogenesis

The production of sperm in the seminiferous tubules in the testes

SEXUAL REPRODUCTION


In what order are these cells developed?:


Spermatid, spermatagonia, spermatoza, spermatocyte

1. Spermatagonia


2. Spermatocyte


3. Spermatid


4. Spermatoza

SEXUAL REPRODUCTION


In what order are these cells developed?:


Primary oocyte, secondary oocyte, oogonia

1. Oogonia


2. Primary oocyte


3. Secondary oocyte

SEXUAL REPRODUCTION


Explain the function of primodial follicles in oogenesis

Contain primary oocyte egg cells arrested in prophase I

SEXUAL REPRODUCTION


What hormone does the corpus luteum produce?

Progesterone

SEXUAL REPRODUCTION


What is the purpose of sertoli cells?

To provide nurishment to developing spermatoza

SEXUAL REPRODUCTION


What does the hormone FSH do during the menstrual cycle?

Triggers the continued division of a few primary oocytes

SEXUAL REPRODUCTION


Describe the function and features of the zona pellucida in eggs

* Jelly layer made from glycoprotein


* Acts as a sperm barrier

SEXUAL REPRODUCTION


Describe the function and features of the corona radiata in eggs

* External layer of the egg


* provides support and nourishment

SEXUAL REPRODUCTION


Describe the function of the cortical granulles in eggs

* After fertilization, releases its contents causing the cortical reaction to prevent polyspermy

SEXUAL REPRODUCTION


Describe the function of the acrosome cap in sperm

Contains enzymes needed to break past the jelly barrier/zona pellucida in eggs

SEXUAL REPRODUCTION


What is external fertilization?

The fusion of gametes outside the body of a parent, common in aquatic life

SEXUAL REPRODUCTION


Describe capacitation its purposeduring intercourse and

* When chemicals released by the uterus dissolve the sperms cholesterol coat


* Improves sperm motility


* destables the acrosome cap to improve acrosome reaction

SEXUAL REPRODUCTION


Describe the acrosome reaction during fertilization

* The sperm breaks through the zona pellucida using enzymes stored in the acrosome cap


* the acrosome fuses with the jelly coat and releases enzymes that soften the glycoprotein


* the sperm can now reach the exposed docking protein on the eggs membrane

SEXUAL REPRODUCTION


Describe the cortical reaction post fertilization

* After fertilization, cortical granulles release enzymes into the zona pellucida to harden and thicken the glycoprotein layer, to prevent ad


* this also destroys the sperm docking proteins.