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14 Cards in this Set
- Front
- Back
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Rhinitis is caused by either ____ or _____
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drug-related or anatomic inflammatory
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rhinitis
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chronic airway inflammation may lead to irreversible airway obstruction
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in rhinitis ___ are increased
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Serum IgE levels
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steps required for sensitization of a patient to antigens
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1. active-mobilize the patient's immune system
2. passive-administer reagents |
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examples of passive-administered reagents
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IVIG, monoclonal antibodies, cytokines, anti-cytokines, previously activated autologous cells- T cells and DC
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examples of active-mobilize the patient's immune system
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infections/vaccines
vaccines for cancer altered peptide ligands |
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synthesis of IgE is regulated by
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T helper and suppressor lymphocytes and their subtypes (Th2 upregulation) and cytokines (IL-4)
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Is IgE deficiency associated with pathology?
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no
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RAST indications
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severe dermatitis, dermatographism, anaphylaxis with previous skin testing
continuous antihistamines uncooperative patient |
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anaphylaxis symptoms
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hypotension, bronchoconstriction, urticaria/angioedema, and abnominal pain/diarrhea
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occasionally anaphylaxis is ___mediated
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IgG + Complement
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____ is a marker of anaphylaxis
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tryptase
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tryptase is
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stored in granules and is actively released during degranulation
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alpha protryptase is
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constitutively released, reflects the total mast cell population
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