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17 Cards in this Set
- Front
- Back
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Diuretics used in hypertinsion
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Tiazide- mild
furosemide- moderate-severe |
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Sympathoplegics
CNS active |
alfa 2 agonists: clonidin, methyldopa (activated to become methynorepinephrine
Decrease sympathetic outflow |
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Sympathoplegics
clonidin edverse effects |
severe rebound hypertension if the drug is suddently stopped.
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Sympathoplegics
Methyldopa edverse effects |
Hemolitic anemia ans sedation
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Sympathoplegics
Ganglion blockage |
Nicotinic blockers - Hexamethonium and trimethaphan
Advers effects: severe orthostatic hypotension, constipation, blurred vision sexual dysfunction |
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Sympathoplegics
Postganglionic blockers |
Reserpine
Guanethidine MAO inhibitors |
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Sympathoplegics
alfa blockers |
release vascular resistance
alfa 1 selective- prozasin edverse effects- orthostatic hypotension + compensatory tacchycardia |
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Sympathoplegics
beta blockers |
Propranolol
edverse effects- sleep disturbance, sedation, impotence, asthma, cardiac disturbance |
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Vasodilators
old generation |
Hydralazine- release NO from the endothel. tox- tacchycardia ans lupus like syndrome.
Minoxidil- become minoxidil sulfate. K channel opener/ Tox- hirsutism' pericardial abnormalities |
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Vasodilators
Ca channels blockers שמות התרופות |
Nifedipine, Verapamil, Diltiazem
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Vasodilators
Ca channels blockers Advers effects |
constipation, flussing, cardiac disturbance, diziness
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Vasodilators
Nitroprusside and Diazoxide |
parenteral, given in hypertension emergency
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Vasodilators
Nitroprusside effect |
Release NO from the drug itself
Tox - hypotension, tacchycardia |
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Vasodilators
Diazoxide פרוט |
opens K channel
reduce insulin release Tox - hypotension, hyperglycemia |
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Vasodilators
Fenoldopam |
acts on dopamine receptors - arterial vasodilation of short durtion (10min) iv
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Angiotensin antagonists
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ACE inhibitor- captopril
Angiotensine 2 receptor blocker- losartan |
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Angiotensin antagonists
captopril effects + toxicity |
reduction of AT2, aldosterone
increase in kinin family VD Tox- cough + renal damage (במיוחד בעובר) |
