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4 Cards in this Set
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Examples of Ag associated with immune complex disease:
infectious agents: bacteria, virus, fungi drugs or chemicals: foreign serum, heroin |
bacteria: streptococci, T. pallidum --> glomerulonephritis
virus: hepatitis B --> polyarteritis nodosa fungi: actinomycetes --> Farmer's lung foreign serum --> serum sickness (GMN, pneumonitis) heroin --> glomerulonephritis |
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anthus rx
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at the site on injection of hormone or Ig
rx pathways are the same as other organs local rx: erythema |
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poststreptococcal glomerulonephritis
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antigen: streptococcas Ags (type 12, 4, 1 group A b-hemolytic streptocci)
high Ab titer (hyperimmune response and restrict the glomerulus) hypercellularity of glomerulus clinical manifestation: low urine volume (oliguria) --> mild hypertensive, urine contains blood and protein, malaise and fever (mediators are produced) |
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Hypersensitivity pneumonitidies (extrinsic allergic alveolitis)
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Farmers lung - M. faeni
Mushroom pickers lung - M. faeni Humidifier/AC pneumonitis - thermophilic actinomycetes pigeon breeder lung - droppings detergent workers lung - bacillus subtilus enzymes |
