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15 Cards in this Set

  • Front
  • Back
what is homeostasis?
maintaining the constancy of internal environments
what is negative feedback?
works with an error signal to approximate the set point. effectiveness can be described in terms of sensitivity, how fast, etc
what are the components of a negative feedback loop?
signal detector, effector, evaluator
what is feed forward?
systems compensate for changes before they happen
what is positive feedback?
a change promotes further change in the SAME DIRECTION; ex: blood clots
input must match _____-
OUTPUT!!!!@#@!#!@
how can intercellular signaling be classified?
direct contact, local diffusion, long distance
what are gap junctions
small pores directly connecting the cytoplasm of adjacent cells
what are gap junctions made of
connexins
what is paracrine?
chemical released into the interstitial fluid to influence cells within a localized area
what is autocrine
acting on the same cell as the cell that released them
what are messenger molecules
how does the sending cell regulate the signal being sent,
what is a receptor?
protein that binds to the messenger molecule; interaction with this and the protein elicits a response
what is a g-protein
couples the receptor to an effector mechanism to amplify the signal;

dag activates pkc
IP3 increases Ca++
how does calcium act as a second messenger?
it binds to calmodulin