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58 Cards in this Set
- Front
- Back
CNS
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brain and spinal cord
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cranial nerves
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12 pairs
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Spinal nerves
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31 pairs
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Somatic Nervous System
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-voluntary, nervous system, concious control
-skeletal muscles |
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Autonomic Nervous System (ANS)
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-involuntary nervous system
-2 divisions: sympathetic and parasympathetic |
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Sympathetic Division
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THE E DIVISION
-exercise, excitement, emergency,embarrassment -"Flight or Fight" |
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Parasympathetic Division
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THE D DIVISION
-digestion, defecations, diuresis (urination) -"Breed and Feed" |
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excitability
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respond to changes in stimuli and produce electrical signals
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conductivity
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can transfer the impulse along the neuron
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Neuroglia / Glial Cells
6 Types |
supporting cells
half of the mass of the brain don't conduct nerve impulses (no excitability/conductivity) |
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Astrocytes
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attach neurons to capillaries, control chemical environment (ions, neurotransmitters) around neuron
physical support |
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Microglial cells
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monitor health of neurons and transform into macrophages to engulf microorganisms and debris to protect neurons
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Ependymal Cells
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circulate cerebrospinal fluid
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oligodendrocytes
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produce myelin sheaths in CNS
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Schwann Cell
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form myelin sheaths around large nerve fibers in PNS
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Satellite Cells
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function like astrocytes, but in PNS
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Neurons
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specialized cells that conduct nerve impulses
very long lived lose ability to divide high metabolic rate |
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Biosynthetic Center
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cell body - cytoplasm and nucleus
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nuclei
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cluster of nerve cell bodies within CNS
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Ganglia
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clusters of cell bodies along the nerves of the PNS
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Dendrites
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receive signals from other neurons
highly branched conduct towards cell body over short distances |
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Axons
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generate and conduct electrical signals away from the cell body, 1 per neuron
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Nodes of Ranvier
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gaps between adjacent Schwann cells on the axon, unmyelinated
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sensory (afferent) neurons
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from skin or internal organs to CNS
cell bodies usually in ganglia |
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motor (efferent) neurons
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impulses from CNS to effector organs
cell bodies usually in CNS |
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interneurons (association) neurons
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impulse from sensory to motor neuron
within CNS 99% of neurons in body most are multipolar |
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Average Resting Membrane Potential for Neurons:
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-70mV (-40mV to -90mV)
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graded potentials
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short-lived, local changes in membrane permeability, short distance
current flow decreases with distance, degrades |
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depolarization
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inside of the membrane becomes less negative
increases the chance of a nerve impulse |
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hyperpolarization
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inside of cell becomes more negative
decreases the probability of a nerve impulse |
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action potentials
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current flow does NOT decreases with distance
Only occurs in muscle cells and axons of neurons |
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How fast can a nerve impulse travel?
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100 - 300 ft/sec
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How much does a typical membrane have to be depolarized to reach threshold
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15 - 20 mV (happens are about -55mV)
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What is the total amplitude change during a nerve impulse?
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-70mV to 30mV, so 100mV total
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Inactivation Gates
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Block the voltage-gated sodium channels soon after they open
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repolarization
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the inside of the cell becomes more negative (after K+ ion gates open)
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Absolute refractory period
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Time following the production of a nerve impulse during which the neuron will NOT respond to a 2nd stimulus
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Relative refractory period
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time following the production of a nerve impulse during when it is more difficult to illicit a response
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How does Novocaine work?
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block the opening of voltage-gated Na+ channels.
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Excitatory Neurotransmitters
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act to increase postsynaptic membrane permeability to Na+
cause EPSPs |
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EPSP's
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Excitatory Postsynaptic Potentials, local graded depolarization
help bring membrane to threshold |
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Inhibitory Neurotransmitters
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act to increase membrane permeability to K+ or Cl-
cause IPSPs |
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IPSP's
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Inhibitory Postsynaptic Potentials, local graded hyperpolarizations
take membrane away from threshold |
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Glutamate
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excitatory neurotransmitter
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serotonin
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inhibitory neurotransmitter
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acetylcholine
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excitatory to skeletal muscle, but inhibitory to some visceral organs (heart)
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Synaptic Integration
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Summing of all the separate signals coming to a neuron
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Temporal Summation
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time, one neuron sends repeated signals
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Spatial Summation
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depends of the location of the synapses in relation to the axon
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anterior horns
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location of neural cell bodies in the spinal cord
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ventral roots
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contain motor (efferent) fibers
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Dorsal roots
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contain sensory (afferent) fibers
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Multiple Sclerosis
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an autoimmune disease and a "demylination disorder"
myelinated areas on axon in CNS are destroyed and replaced by plaque |
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Why do you get abnormal sensations (tingling) or numbness, uncoordinated during MS?
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Because the myelin sheath electrically insulates so if it is destroyed you can get random signals.
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How many neurons are interneurons?
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99%
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How many cranial sensory nerves?
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3
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How many cranial motor nerves?
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5
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How many cranial mixed nerves?
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4
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