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58 Cards in this Set

  • Front
  • Back
CNS
brain and spinal cord
cranial nerves
12 pairs
Spinal nerves
31 pairs
Somatic Nervous System
-voluntary, nervous system, concious control
-skeletal muscles
Autonomic Nervous System (ANS)
-involuntary nervous system
-2 divisions: sympathetic and parasympathetic
Sympathetic Division
THE E DIVISION
-exercise, excitement, emergency,embarrassment
-"Flight or Fight"
Parasympathetic Division
THE D DIVISION
-digestion, defecations, diuresis (urination)
-"Breed and Feed"
excitability
respond to changes in stimuli and produce electrical signals
conductivity
can transfer the impulse along the neuron
Neuroglia / Glial Cells
6 Types
supporting cells
half of the mass of the brain
don't conduct nerve impulses
(no excitability/conductivity)
Astrocytes
attach neurons to capillaries, control chemical environment (ions, neurotransmitters) around neuron
physical support
Microglial cells
monitor health of neurons and transform into macrophages to engulf microorganisms and debris to protect neurons
Ependymal Cells
circulate cerebrospinal fluid
oligodendrocytes
produce myelin sheaths in CNS
Schwann Cell
form myelin sheaths around large nerve fibers in PNS
Satellite Cells
function like astrocytes, but in PNS
Neurons
specialized cells that conduct nerve impulses
very long lived
lose ability to divide
high metabolic rate
Biosynthetic Center
cell body - cytoplasm and nucleus
nuclei
cluster of nerve cell bodies within CNS
Ganglia
clusters of cell bodies along the nerves of the PNS
Dendrites
receive signals from other neurons
highly branched
conduct towards cell body over short distances
Axons
generate and conduct electrical signals away from the cell body, 1 per neuron
Nodes of Ranvier
gaps between adjacent Schwann cells on the axon, unmyelinated
sensory (afferent) neurons
from skin or internal organs to CNS
cell bodies usually in ganglia
motor (efferent) neurons
impulses from CNS to effector organs
cell bodies usually in CNS
interneurons (association) neurons
impulse from sensory to motor neuron
within CNS
99% of neurons in body
most are multipolar
Average Resting Membrane Potential for Neurons:
-70mV (-40mV to -90mV)
graded potentials
short-lived, local changes in membrane permeability, short distance

current flow decreases with distance, degrades
depolarization
inside of the membrane becomes less negative
increases the chance of a nerve impulse
hyperpolarization
inside of cell becomes more negative
decreases the probability of a nerve impulse
action potentials
current flow does NOT decreases with distance
Only occurs in muscle cells and axons of neurons
How fast can a nerve impulse travel?
100 - 300 ft/sec
How much does a typical membrane have to be depolarized to reach threshold
15 - 20 mV (happens are about -55mV)
What is the total amplitude change during a nerve impulse?
-70mV to 30mV, so 100mV total
Inactivation Gates
Block the voltage-gated sodium channels soon after they open
repolarization
the inside of the cell becomes more negative (after K+ ion gates open)
Absolute refractory period
Time following the production of a nerve impulse during which the neuron will NOT respond to a 2nd stimulus
Relative refractory period
time following the production of a nerve impulse during when it is more difficult to illicit a response
How does Novocaine work?
block the opening of voltage-gated Na+ channels.
Excitatory Neurotransmitters
act to increase postsynaptic membrane permeability to Na+

cause EPSPs
EPSP's
Excitatory Postsynaptic Potentials, local graded depolarization

help bring membrane to threshold
Inhibitory Neurotransmitters
act to increase membrane permeability to K+ or Cl-
cause IPSPs
IPSP's
Inhibitory Postsynaptic Potentials, local graded hyperpolarizations

take membrane away from threshold
Glutamate
excitatory neurotransmitter
serotonin
inhibitory neurotransmitter
acetylcholine
excitatory to skeletal muscle, but inhibitory to some visceral organs (heart)
Synaptic Integration
Summing of all the separate signals coming to a neuron
Temporal Summation
time, one neuron sends repeated signals
Spatial Summation
depends of the location of the synapses in relation to the axon
anterior horns
location of neural cell bodies in the spinal cord
ventral roots
contain motor (efferent) fibers
Dorsal roots
contain sensory (afferent) fibers
Multiple Sclerosis
an autoimmune disease and a "demylination disorder"
myelinated areas on axon in CNS are destroyed and replaced by plaque
Why do you get abnormal sensations (tingling) or numbness, uncoordinated during MS?
Because the myelin sheath electrically insulates so if it is destroyed you can get random signals.
How many neurons are interneurons?
99%
How many cranial sensory nerves?
3
How many cranial motor nerves?
5
How many cranial mixed nerves?
4