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146 Cards in this Set

  • Front
  • Back
How many different types of cell are there?
200
Each cell types allows for ____ function
different
There are over how many cells in the body that vary in shape and size and yet have so much in common?
75-100
Cells ____ with each other
interact
Chemically our cells are almost 1._____ , but visually and functionally they are as _____ as animals in a zoo
1. alike
2. different
what is unique about a red blood cell?
there is no nucleus; therefore, it cannot reproduce
what is unique about a nerve cell?
the branches are used for electrical impulses (ions)
what is unique about a sperm cell?
they are the SMALLEST cell in the body and have specialized flagella that help the sperm move.
what is the largest cell in the body?
female egg
what is the smallest cell in the body?
the sperm
what is unique about smooth muscle cells?
they are used for contractions. such as in the stomach and liver
what is unique about epithelial cells?
they are used for absorption, secretion, and movement of material
the cell is the 1. ____ structure of all 2. _____ ______
1. basic
2. living matter
What are the 4 steps in cell theory?
1. Cell is basic structure and functional unit of life.

2. Activity of an organism depends on individual and collective activity of its cells.

3. Biochemical activity of cell are dictated by relative # of specific sub-cellular structures.

4. Continuity of life as a cellular basis.
What a cell does and how it functions depends on ______
organelles
A _____ cell includes many different structures.
composite
A cell consists of what three main parts?
nucleus, the cytoplasm, and the cell membrane
Within the 1. ____ are specialized organelles that perform 2 ____ ____ for the cell.
1. cytoplasm
2. specific functions
What is the basis of most diseases?
lost of cellular homeostasis
What are the three main functions of a plasma (cell) membrane?
1. movement of substances in and out of the cell.

2. participate in signal transduction.

3. help cells adhere to other cells.
1. _____ is stimulation from outside the cell that is 2. _____ into the cell.
1. Transduction

2. Transmitted
The cell membrane is extremely 1 ____ and 2. _____ _____ (controls what comes in and out of cell)
1. Thin

2. Selective Permeable
What is on top of the plasma membrane (outside) that is a carbohydrate which contains sugar on protein. Also it allows stickiness and adhesion
GLYCOCALYX
Molecules that are soluble in lipids and can pass through the lipid bilayer?
oxygen, CO2, steroid hormones
The molecules that are impermeable to phospholipid bilayer?
amino acids, sugars, proteins, nucleic acids, and some ions, water
What does the DNA tell the RNA about proteins?
HOW to instruct to proteins. Thus, all the information is in the cell.
Embedded 1. _____ molecules strengthen the membrane and help make the membrane 2._____ _____ to water-soluble molecules
1. cholesterol

2. less permeable
Many proteins are found in the cell membrane, including 1. _____ 2. ____
1. Transmembrane proteins

2. Peripheral membrane proteins
Name some functions of the cell membrane proteins?
receptors on the cell surface, starting signal transduction, aid pass of molecules and ions
Membrane proteins perform a variety of ______ and vary in ____
Functions, Shape
Define Globular proteins
communication channels

--> amino acids and sacharides enter the cell when the channel is opened.
Why do some proteins on the cell membrane have carbohydrates attached to them?
These complexes are used in cell identification.
membrane proteins called ____ ____ _____ help determine one cell's interaction with others.
cellular adhesion molecules (CAMs)
transmembrane proteins acts as _______
channels
what diffusion requires no energy?
PASSIVE, from high to low concentration
what diffusion require energy?
ACTIVE, from low to high concentration
A membrane protein exposed to the outside of the cell may have binding site with a specific shape and fits the shape of a chemical messenger, such as a hormone. The external signal may cause a change in shape in the protein that initiates a chain of chemical rxns in the cell.
Receptors for signal transduction
Elements of the _____ (cell's internal support) and the ____ _____ fibers and other substances outside the cell) may be anchored to membrane proteins, which may help maintain the shape and fix the locations of certain membrane proteins. Others play a role in cell movement or bind adjacent cells together.
Attachment to the cytoskeleton and extracellular matrix (ECM)
Membrane proteins of adjacent cells may be hooked together in various kinds of _____ _____. Some membrane proteins (CAMs) of this group provide temporary binding sites that guide cell migration and other cell-to-cell interactions.
INTERCELLULAR INTERACTION --> Communication of cell back and forth to each other
what recognition do Some glycoproteins (proteins bonded to short chains of sugars) serve as identification tags that are specifically recognized by other cells.
Cell-Cell RECOGNITION
Define Desmosomes
ANCHORING (STRENGTHEN) junctions that bind adjacent cells together and help form internal tension reducing network of fibers
Define Tight Junctions
Impermeable molecules that loop around and tie membrane together. Helps things to not get in between the cell wall
Define Gap Junction
Communication junctions allowing small ions and small molecules to pass from one cell to another
What does a cytoplasm consist of?
1. a clear liquid known as CYTOSOL

2. a supportive cytoskeleton

3. Networks of membranes and organelles.
What is made up of membranes, flattened sacs, and vesicles, and provides a tubular transport system inside the cell?
Endoplasmic Reticulum
What ER functions in protein synthesis?
Rough ER
What ER functions in lipid (cholesterol) synthesis?
Smooth ER
____ are the machinery of the cell
Organelles
Where are ribosomes found?
With rough ER (exported out of cell) and are scattered throughout the cytoplasm (used in the cell).
What are ribosomes composed of? What do they provide?
Composed of protein and RNA. They provide a structural support for the RNA molecules that together in protein synthesis.
What is composed of flattened sac and connected to the ER, that refines, packages, modifies, and delivers proteins?
Golgi apparatus
How are vesicles formed?
formed on ER travel to the Golgi apparatus which modifies their contents chemically. They are specialized to receive glycoproteins (sugars bound to protein). The glycoproteins pass from layer to layer through the Golgi. The altered glyocproteins branch off and form transport vesicles.
When a vesicles moves to the outside of the cell, this is called?
exocytosis
the "receiving" side of the Golgi apparatus?
CIS
The "shipping" side of the Golgi apparatus?
TRANS
____ are the 'garabage disposal' of the cell and contain digestive enzymes to break up old cell components and bacteria
Lysosomes
_____ contain enzymes that function in the synthesis of bile acids, breakdown of lipids, degradation of rare biochemicals, and detoxification of alcohol. They are abundant in the liver and kidney cells.
Peroxisomes
____ the powerhouse of the cell and contain enzymes needed for aerobic respiration.
Mitochondria
the inner membrane of the mitochondrion is folded into _____ which hold the enzymes needed to make ATP (adenosine triphosphate)
cristae
Mitochondria have their own ____ & ___, therefore being able to reproduce themselves (muscles have more if you work out)
DNA & RNA
lysosomes are found in _____
macrophages
what disease lacks lysosomes and found in middle eastern jews?
Tay Sachs
Define Aerobic Respiration
Presence of OXYGEN when more ATP is produced inside and outside of mitochondria
Define Anaerobic Respiration
WITHOUT OXYGEN
______ and ____ are thin, threadlike structures that serve as the cytoskeleton of the cell.
microfilaments and microtubules
_______ are made of actin, cause various cellular movements. they help support framework
microfilaments
_____ made of globular protein tubulin, are arranged in 9 + 2 pattern of tubules, that is 9 outside tubules form a ring around two inner ones. MOVEMENT
microtubules
_____ are made up of tough insoluble protein fibers constructed like woven ropes
Intermediate Filaments
______ is structure made up of two hollow cylinders called centrioles that function in the separation of chromosomes during cell division. During cell division (mitosis) they distribute chromosomes to newly formed cells.
Centrosome
_____ & ____ are motile extensions from the cell; shorter cilia are abundant on the free surfaces of certain epithelial cells (respiratory linings), and a lengthy flagellum can be found on sperm cells
Cilia & Flagella
What is the purpose of Cilia?
Move debris, structure, mucus ALONG A CELL WALL.

*Does not move the cell
What is the purpose of Flagella?
A single tail that moves the cell, sperm
____ form from part of the cell membrane or the Golgi and store materials.
Vesicles
____ form from part of the cell membrane or the Golgi and store materials.
Vesicles
What are the three major parts of the nucleus?
1. Nuclear membrane
2. Nucleolus
3. Chromatin
______ _____ is where the nuclear pores of the nucleus are, so RNA can get out
nuclear membrane
______ is composed of RNA and protein and is the site of ribosome production
nucleolus
______ consists of loosely coiled fibers protein and DNA. The DNA contains the information for protein synthesis
chromatin
____ regulate protein synthesis
nucleus
_____ detoxification, lipid synthesis, and calcium ion storage
smooth ER
_____ protein synthesis and making transport vesicles
rough ER
_______ modification and storage making transport vesicles
golgi
_____ storage and transport
vacuole
____ anchoring for mitosis
centriole
where does cellular respiration occur?
mitochondria
intracellular digestive enzymes, breakdown of old organelles
lysosomes
_____ is caused by random motion and involves the movement of molecules from an area of greater concentration to one of lesser concentration until equilibrium is reached.
Diffusion
cells are composed mainly of ____ based ingredients
carbon
____ ____ uses membrane proteins that function as carriers to move molecules (such as glucose) across the cell membrane.
Facilitated Diffusion (Passive)
what limits the rate of the facilitated diffusion process?
the number of carrier molecules in the cell membrane
Define osmosis
a special case of diffusion in which water moves from an area of greater concentration (where there is less osmotic pressure) across a selectively permeable membrane to an area of lower concentration (where there is greater osmotic pressure).
____ ____ is the ability of osmosis to lift a volume of water.
osmotic pressure
A solution that has the same osmotic pressure is called _____
isotonic
A solution with the higher osmotic pressure than body fluids is ____
hypertonic (draw water up-shrink)
A solution with lower osmotic pressure than body fluids____
hypotonic (increase water, lyse)
____ is the amount of water in each cell
tonicity
A solution that has the same osmotic pressure is called _____
isotonic
A solution with the higher osmotic pressure than body fluids is ____
hypertonic (draw water up-shrink)
A solution with lower osmotic pressure than body fluids____
hypotonic (increase water, lyse)
____ is the amount of water in each cell
tonicity
What does diffusion enable?
It enables oxygen and CO2 molecule to be exchanged between the air and the blood on the lungs, and between blood and tissue cells.
because of _____ ____, pressure molecules can be forced through membranes by the process of filtration. Blood pressure is an example
hydrostatic pressure (FILTRATION)
____ ____ of fat soluble molecules directly through the phospholipid bilayer
simple diffusion
______ _____ via a protein carrier specific for one chemical; binding to a substrate causes shape change in transport protein
carrier-mediated facilitated diffusion
_____ ____ through a channel protein, mostly ions selected on basis of size and shape
channel-mediated facilitated diffusion
how much cell's energy supply is used to fuel active transport?
40%
How does Active Transport work?
The union of the specific particle to be transported with its carrier protein triggers the releases of cellular energy (ATP), which in turn alters the shape of the carrier protein, releasing the particle to the other side of the membrane.
what particles are ACTIVELY transported?
sugars, amino acids, and sodium, potassium, calcium, and hydrogen ions, as well as nutrient molecules in the intestine.
in _____, molecules that are too large to be transported by other means are engulfed by an _____ of the cell membrane and carried into the cell surrounded by a ______.
endocytosis, invagination, vesicle.
what are the three forms of endocytosis?
1, pinocytosis
2. phagocytosis
3. receptor-mediate endocytosis
what form of endocytosis engulfs liquids?
pinocytosis
what form of endocytosis takes larger particles, such as a white blood cell engulfing a bacterium,
phagocytosis
what form of endocytosis allows very specific molecules (ligands) that pair up with specific receptors on the cell surface.
receptor-mediated endocytosis
most vesicles are protein coated, endocytosis is coated by what protein?
clathrin
True or False endocytosis requires energy?
True
what does the cell cycle consist of?
interphase, mitosis, cytokinesis, and differentiation
True or False, cells divide continually?
False, cells have a maximum number of times they can divide because of built in clocks called telomere on the tips of chromosome
What happens to telomeres each time a cell divides?
a telemore breaks off and its gets smaller until it can no longer reproduce resulting in cell death
What are the steps in interphase?
G1, S, G2
what happens in G1 on interphase?
The organelles are duplicated and the cell grows (6-8 hr life span)
what does the cell cycle consist of?
interphase, mitosis, cytokinesis, and differentiation
True or False, cells divide continually?
False, cells have a maximum number of times they can divide because of built in clocks called telomere on the tips of chromosome
What happens to telomeres each time a cell divides?
a telemore breaks off and its gets smaller until it can no longer reproduce resulting in cell death
What are the steps in interphase?
G1, S, G2
what happens in G1 on interphase?
The organelles are duplicated and the cell grows (6-8 hr life span)
What happens in the S phase of interphase?
DNA replication
What happens in the G2 phase of interphase?
Growth of pattern of the cell continues. Enzymes and different proteins are duplicated and ready to divide. 4-6 hrs (shorter than G1 phase)
_____ is a careful orchestrated division of the nucleus of the cell that results in each daughter cell an exact copy of the mother genetic material.
Mitosis
____ is where four cells (sperm or ova) are produced, each contains half of the parents cell's genetic information
Meiosis
What are the four stages of mitosis?
prophase, metaphase, anaphase, telophase
_____ begins during anaphase of mitosis and continues as a contractile ring pinches the two new cells
cytokinesis
what happens in the telophase of mitosis?
this is the final stage in mitosis, its is where when the nuclear envelope reappears, chromosomes have completed their migration and begin to unwind.
_____ id s form of cell death that is a normal part of development
apoptosis
what happens in apoptosis?
caspases enzyme is released and it cleans everything up, destroys the DNA so it wont disrupt other cells. Lysosomes eat it up.
what are the three phases if cellular respiration?
glycolysis, citric acid cycle, electron transport chain
each molecules goes through the three stages of cellular respiration how many times?
twice
what happens in the glycolysis stage of cellular respiration?
anaerobic (w/o oxygen). The initial stage of breakdown of glycolysis in the cytoplasm.
what happens in the citric acid cycle?
aerobic in the mitochondria, 4 ATPS
electron transport chain?
up to 34 ATP's in mitochondria, aerobic. MOST OF THE ATP COMES FROM HERE
what is the importance of glucose?
it is the energy source of the cell where OXYGEN is used to MAXIMIZE energy by mitochondria
energy is the breaking of _____
bonds
what does glucose make?
2 pyruvate acids which go into the mitochondria
electrons are carried via ____
NADH (nicotinanide Adenine dinculeotide)
DNA going into RNA is
transcription
RNA to PROTEIN is
translation
A triplet of a nucleotide in messenger RNA is called what
a codon