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17 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Structurally similar to thiazide diuretics, but has opposite effect of Na and water retention. Very potent, and only given IV for hypertension emergencies.
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What is diazoxide?
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Causes hyperglycemia.
Thiazide, diaz . . . Its backwards. |
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Recombinant BNP, vasodil vascular smooth muscle. Sometimes given during acute CHF to attenuate dyspnea.
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What is natrecor (nesiritide)?
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Opens K channels resulting in hyperpolarization of vascular smooth muscle so that contraction is less likely.
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What is Minoxidil?
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Rogaine.
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May act through the release of NO and by opening K channels. Shorter acting than Rogaine and mainly acts on arterioles and not on veins.
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What is hydralazine?
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A component of Bi-Dil
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A dopamine agonist that is reported to have a selective actiona t dopamine D1 receptors, leading to vasodilation.
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What is fenoldopam?
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Some group added on to dopamine.
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Anti-esstrogen used as a breast cancer treatment, is an agonist in bone and uterus (bad)
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What is Tamoxifen?
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Also and anti estrogen in both breast and uterus, agonist in bone.
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What is raloxifene?
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Can exacerbate hot flashes.
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Non-steroidal estrogen modifier, used to treat infertility. reduces neg feedback, so inc FSH and LH, so stim ovulation
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What is Clomiphene?
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Associated with multiple births. Think cloning.
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Anti-estrogen, approved for tamoxifen-refractory metastatic breast cancer in post-menopausal women
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What is Fluvestrant?
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When your flow is abs-ant.
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A testosterone deriv (has anti-estrogen and anti-androgen activity) that inhibits gonadotropin release. Used to treat endometriosis.
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What is Danazol?
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Side effects: hirsutism, weight gain, acne: makes danielle into a dan.
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Potent competitive antagonist of both progesterone and glucocorticoid receptors, used to terminate early pregancy.
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What is mifepristone?
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Non-steroidal inhibitor of aromatase, used to treat breast cancer. Side effs: lethargy, rash ataxia, nausea.
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What is anastrozole?
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anti-astrogen
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Inhibs the first step in synth of all steroids, and also inhib aromatase. Used for breast and prostate cancer and in Cushing's.
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What is Aminoglutethimide?
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It's just a generic drug name with a lot of group names in it.
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Potent, non-steroidal androgen receptor antagonist. Used to treat metastatic prostate cancer. Side effs: hepatotox, gynecomastia, hirsutism.
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What is Flutamide?
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Makes him kinda flute-y. Also bicalutamide.
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A progestin with anti-androgen activity. Used for prostate cancer.
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Cyproterone acetate
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lyce the prostate.
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A mineralocorticoid receptor antagonis and weak androgen antagonist. Also inhibits testosterone synth. Approved to tx hirsutism.
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What is spironolactone?
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Drug also has another use as an anti-hypertensive.
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Inhibitor of 5 alpha reductase. Used to treat BPH. Side effs: ejaculation disorders
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What is Finasteride?
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inhibits the final steroid development.
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