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62 Cards in this Set

  • Front
  • Back
Which med cannot be combined with ototoxic drugs such as gentamicin
Furosemide
compare uses of Furosemide and Hyrodchlorothaizide
Furosemide for pulmonary edema, edmatous states, HTN

Hydrochlorothiazide: edema, HTN, Diabetes Insipidus
Which med is syncope a problem with
furosemide
what are the adverse effects of furosemide
hypovolema, hypotension,
hyponatremia, hypochloremia, hypokalemia
hyperglycemia, hyperuricemia
dehydration
ototoxicity
low HDL, high LDL and trigly
adverse effects of thiazides
hypovolema, hypotension,
hyponatremia, hypochloremia, hypokalemia
hyperglycemia, hyperuricemia
dehydration
NOT ototoxicity
What diuretic is not good if someone has renal failure
furoseide
which of the diuretics has profound diuresis
furosemide
MOA of furosemide
blocks NaCl and H2o reabsorption
MOA of thiazide
blocks reabsorption of NaCl, promotes excretion of K, Cl, Mg, bicarb
countraindications for furosemide

cautions
pregnancy

caution: DM , gout
contraindications for thiazides

cautions
pregnancy

cuation: DM, gout
drug interactions of furosemide
Digoxin- dysrhyhmias
ototoxic drugs: gentamicin
lithium toxicity
additive effects of other antihypertinsive
NSAIDS blunt diuretic
thiazides work by
reducing blood volume
reducing arterial resistance
furosemide works by
decreasing blood volume
decreasing arterial resistance
Onset of furosemide
IV
PO
IV: 5-2 hrs- used for critical pulmonary edema
PO: 1-8 hrs
nurse must monitor for furosemide
electrolytes, wt, clucose, BP, lipids
onset, peak, duration for thiazide
onset: 2 hrs
peak: 4-6 hrs
lasts: 12 hrs
which diuretic is used with diabetes insipidus
hydrochlorothiazide
which diuretic used for severe heart failure
spironolactone
which med is used to counteract loss of K from other meds?
Amiloride
don't mix which HTN drugs
K sparing diuretics with ACEi, ARB, salt or K supplements
MOA of Spironolactone (K sparing diuretic)
blocks Aldosterone Na/K pump in distal nephron,
Na excreted, K retained
Uses for Spironolactone:
HTN, edema, severe heart failure, primary hyperaldosterone
onset of spironolactone (K sparing diuretic)
up to 48 hours
adverse effects of Spironolactone (K sparing diuretic)
hyperkalemia
endocrine effect
benign/malignant tumor
MOA Triamterene
directly blocks Na/K pump, inhibits ion transport
decreases Na reuptake
adverse effects of triamterene (K sparing diuretic)
hyperkalemia
leg cramps
blood dyscrasis (bone marrow products)
cautiously use triamterene with


never use with
ACEi, ARB,

never use with: K supplements, other K sparing diuretics
adverse effect of Amiloride
hyperkalemia
use for mannitol

route
prophylaxis renal failure
decrease intracranial pressure
decrease intraocular pressure- glacoma

IV: in ICU with urea
beta blockers end in
lol
drug for migraine prophylaxis
beta blockers: (lol)
mainstay drugs for angina
beta blockers
standard drug for heart failure
beta blockers
ACEi, ARB's, beta blockers all are used for
HTN
MI
ACEi used for
HTN
MI
nephropathy and retinopathy
prevent cardiovascular and stroke
use for ARB's
HF
HTN
MI
nephropathy and retinopathy
prevent cardiovascular and stroke
MOA ACEi
supress AII
which causes a supression of vasodilitation,
decrease blood volume,
decrease cardiac remodeling
adverse effects of ACEi
1st dose hypotension
cough
hyperkalemia
renal failure
fetal injury
angioedema: toungue, glottis, pharynx
which med causes cough
ACEi
which meds do you have to watch for angioedema
ACEi, ARB's
drug interactions with ACEi
diuretics: increase 1st does hypotension
additive effect of antihyp drugs
drugs that raise K
NSAIDS decrease ACEi effect
lithium
ACE is contraindicated in
pregnancy
bilateral renal artery stenosis
which med is OK to use with asthma
ACEi
which med cannot use with asthma
beta blocker
what is the advantage of using ARB's
no cough
no hyperkalemia
1st choice drug that inhibits RAAS
ACEi
MOA of ARB's (angiotension receptor block)
blocks ACTION of AII
uses of ARB's
HTN
HF
MI
retinopathy, nephropathy
prophylatic for stroke
adverse advantages for ARB's
higher rigk of hypotension
angeoedema
fetal injury
renal failure
ARBs contraindicated in
pregnancy
renal stenosis
Atenolol, carvedilol, metoprolol, propranolol are what type of meds
beta blockers
use of beta blockers
HTN
HF
MI
migraine prophylaxis
angina
MOA for beta blockers
decrease HR
decrease force of contraction
decrease conduction through AV node
decrease cardiac output
adverse effects of beta blockers
4 B's : bradycardia
blocks AV node
bronchoconstriction
blood sugar
effects of abruptly stopping beta blockers
rebound excitation, increase cardiac activity
hypertensive crisis
bronchodilation
rebound tachycardia
drug interactions between propranolol and insulin/DM patients
propranolol decreases glycogenlysis, thus low blood sugar
problem with insulin which already decreases blood sugar

decreases, masks, tachycardia so diabetic can see signs that their blood sugar is getting low
which drug will be used for pulmonary edema
furosemide
what will happen if K level rises
dysrhythmia and heart attack
MOA of Mannitol
filtered at glomerulus and causes osmotic diuresis, carries water out with it
adverse effects of mannitol
edema
headache
n/v
electrolyte embalance
most often used beta blocker
propranolol