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25 Cards in this Set
- Front
- Back
what is numbers for HTN
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140/90
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sum up drug treatment for HTN
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barorecptors with BB, RAAS with ACE and kidneys with diuretic
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how do diuretics reduce BP
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reduce blood volume, and reduce arterial resistance
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why use loop over thiazide?
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use loop when low GFR
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what do CCB do?
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they dilate arterioles
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ACE ARBS and DRIs do?
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prevent vasocontriction and prevent blood volume expansion
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what does activation of alpha 1 do?
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vasodilation of veins and arteries
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alpha 1 angonists treat
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BPH and HTN
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problem with alpha 1 antagonists
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cause rebound tachy which can cause angina CHF, othro hypo, nasal congestion, no ejac.
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antidotes for alpha 1
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regitine
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example of alpha 1
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prazisin or minipress
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what does B1 do?
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decrease HR, conductivity and contractility- long term- reduce PVR
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clinical uses of BB
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HTN- except AA, MI- best within 12 hours, angina- decrease O2 demand, dysrhymias- slow conduction
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adverse for B1 block
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brady, reduced CO, rebound cardiac excitment, depression, impotence
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adverse for B2 blockes
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bronchoconstriction, hypglycemia
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BB interactions
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CCB, insulin, dig (brady), diuretics (hypo), antacids
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who is risk for taking BB
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sinus brady, AV heart block, caution in HF, ( nonselective) asthma, diabetes, and allergies- suppresses epi
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signs of heart failure
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SOB, night coughs, swelling of extremities
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what do ACES do?
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suppress Angio which dilates arterioles and veins, suppress aldo- Increasing K, decrease Na, increase kinins- help prevent remodeling
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what does BNP do and what is the value?
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antagonizes angio and < 100
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adverse of ACE
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hyperkalemia, cough, 1st dose Hypo, angioedema, caporil (rash, dysguesia, and neutopenia), pregnancy, renal stenosis problems
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ACE interactions
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diuretics( 1st dose). antiHTN meds,drugs that raise K, lithium levels increase, NSAIDs (reduce hypo effects)
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how are ARBs and ACEs different
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ARBs do not help remodeling and they do not cause cough or hyperkalemia
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BB help HF how?
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improve EF, excercise tolerance, prolongs survival but takes 1-3 months
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example of DRI
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Aliskiren
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