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85 Cards in this Set

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  • Back
What consist of the conducting portion of the respiratory system?
Nasal cavity, nasopharynx, mouth, oropharynx, larynx, trachea, primary bronchi, secondary bronchi (lobar), bronchioles, and terminal bronchioles
What consist of the respiratory portion of the respiratory system?
Respiratory bronchioles, alveolar ducts, alveolar sacs, alveoli
What are the three layers of olfractory epithelium?
Bottom to top

1.) Basal cells
2.) Sustentacular cells
3.) Olfactory cells
Where can you find olfractory epithelium?
Superior part of the lateral wall of the nasal cavity

and the same area of the nasal septum, and roof of the nasal cavity
In which structures of respiratory system will you see cartilage?
Before the bronchioles
What is another name for respiratory epithelium?
Pseudostratified columnar epithelium with ciliar and goblet cells
Why are there lots of venus sinus in the nose?
Venus sinus is just a collection of tiny veins that are lined by the endothelium to warm and moist the air enter the nose
What are bowman's gland?
Serous glands in the CT region

Functions:
1.) moisten surface of the olfactory epithelium in order to dissolve and wash away odorants
What is the epithelium found in nasopharynx?
Respiratory epithelium
What is the epithelium found in oropharynx and laryngopharynx?
Nonkeratinized, stratified squamous, because that area is subjected to mechanical abrasion
What are swell bodies?
An excess of venous sinuses that can engorged with blood and can cause the nose to occlude
What are some distinguishing features of naso-, oro-, or laryngo-pharynx?
Naso - respiratory
Oro - respiratory to non-keratinized stratified squamous
Laryngo - nonkeratinized stratified squamous with cartilage
What is the epithelium of the laryngel side of the epiglottis?
Respiratory epithelium
How to distinguish trachea on a transverse cut?
Look for the repating pattern of small plates of hyaline cartilage (cross sections of the 'C' rings), subsets of them
Epiglottis contains...
Elastic cartilage
Larynx vs. trachea
The larynx has large plates of cartilage deep to the respiratory epithelium

The trachea contains smaller plates of cartilages (still hyaline)
What is the epithelium of the oral (lingual) side?
Nonkeratinized, stratified squamous
What type of collagen is in elastic cartilage?
Type II collagen
What is the epithelium covering the true vocal cord?
Nonkeratinized, stratified squamous

Designed to withstand and respond to the abrasive nature of rapidly moving air that occurs during speech and coughing
What are the characteristics of true vocal cord (vocal fold)?
1.) nonkeratinized stratified squamous
2.) skeletal muscle
3.) elastic fibers
What are the characteristics of the false vocal cord (vestibular fold)?
1.) respiratory epithelium
2.) mixed seromucous glands
Distinguishing features of trachea?
C-shaped band of hyaline cartilage surrounding most of the lumen

Respiratory epithelium

Smooth muscle band in the posterior aspect of the trachea near the two ends of the hyaline cartilage
Where is the tracheal 'C' rings of cartilage opening? (anteriorly or posteriorly?)
Posteriorly
What is the epithelium of esophagus?
Stratified squamous

1.) keratinized in embryo
2.) non-keratinized after birth
How do distinguish between trachea and bronchus?
Trachea has complete 'C' cartilage whereas bronchus has incomplete 'C' cartilage on a transverse cut
How do distinguish between bronchus and bronchiole?
Bronchus has cartilage, bronchiole does not

Bronchiole also has cuboidal epithelium

Bronchus has respiratory
What are some distinguishing features of bronchus?
Seromucous glands and dense irregular connective tissue between and surrounding the hyaline cartilage plates
How to distinguish between terminal bronchiole and respiratory bronchiole?
Look for the direct branching into 2 respiratory bronchiole, represents the regions of transition between the conduction and respiratory portion of the respiratory system

Both have simple cuboidal
How do you distinguish bt Type I and Type 2 pneumocytes?
Type 1 light center, type 2 darker center

Type 1 squamous shape, type 2 more cuboidal shape
What are the 5 layers of blood-air barrier?
Air to blood

1.) Surfactant
2.) Type I pneumocytes
3.) Fused basal lamina
4.) Endothelium of capillary
5.) RBC
How to distinguish betwewen Type II pneumocytes and dust cells (aka alveolar macrophages)
Both have sorta dark nucleus, but dust cells have a more darly staining cytoplasm
What are the three layers of the heart? (outer to inner)
Epicardium, Myocardium, Endocardium
Which layer of the heart is adipose tissue associated with?
Epicardium
What kinda of junctions connect the Purkinje fibers?
Gap junctions
What is the cardiac skeleton composed of?
Dense CT
What is the purpose of the cardiac skeleton?
Surrounds each valve and serves as an attachment site to cardiac muscle
What are the characteristics of Tunica intima?
Single endothelial layer, BL

Delineate by endothelial cells and inner elastic lamina (IEL)
What are the characteristics of Tunica media?
Helically arranged SM cells with elastin and Type III collagen. Anywhere from 1-40 layers of SM

Delineated by IEL and OEL, with IEL considered as part of the tunica intima
What are the characteristics of Tunica adventitia?
Type I collagen and elastic fibers

SM (longitudinal) are present in large veins
What is vasa vasorum?
Arteries that supply to bigger arteries
What is the largest tunica in a artery?
Tunica media
What is the largest tunica in vein?
Tunica adventitia
Tunica intima characteristics in conducting artery?
Single layer of endothelial cells, longitudinally oriented CT, fibers, fibroblast, and SM
Tunica media characteristics in conducting artery?
Concentrically oriented elastic fibers

Area between elastic fibers is occupied by SM cells, usually >40 layers of cells
Tunica adventita characteristics in conductin artery?
Thin, contains collagen, elastic fibers, and vasa vasorum, and adipose tissue
Where are vasa vasorum located in large veins and arteries?
Tunica adventitia
How to distinguish between muscular artery and arterioles?
Muscular artery has IEL and ELE w SM in between

Arterioles only has a thin tunica and a small tunica media, no IEL and OEL
Fact: Lots of elastic fibers around pulmonary artery
To accommodate the expansion and contraction associated with respiration
How to distinguish between Arterioles and capillaries?
Arterioles: highest muscle to lumen ratio, a few layers of SM

Capillaries: no SM, 1 RBC in diameter, only 1 to several endothelial cells in diameter
How to distinguish between venules and small veins?
Both has several endothelial cell in diameter, no SM

But small veins have bigger diameter, using RBC to measure
How to distinguish between venules and capillaries?
Very similar, but venules are bigger
What are the three types of capillaries?
Continuous, fenestrated, and discontinuous
What kinda of capillaries are sinusoids?
Discontinuous
How do you distinguish between a vein and artery?
SM muscle (cross sections) in the tunica adventital layer of the veins

Only Type I collagen and elastic fibers found in arteries
How to distinguish between lymphatic vessels and veins?
Lymphatic vessels no tunica media or SM, often contain lymph, a pink cellular material with no RBCs
T or F: lymphatic valves are composed of small amount of CT and extend into the lumen of the lymphatic vessels
True
What are the three types of lymphoid tissue?
unencapsulated
incompletely encapsulated
encapsulated
what are the cells of the lymphatic system? (motile and fixed)
Motile - lymphocytes and macrophages

Fixed - epithelial reticular cells and plasma cells
What are the organs of the lymphatic system?
Tonsils, lymph nodes, spleen, and the thymus
What does unecapsulated mean?
No CT surrounding
Which one stains lighter? primary or secondary lymphatic nodules?
Secondary - also called germinal center
Fun fact: Germinal centers = less basophilic
the area has been subjected to the presence of the foreign antigens
What lymphatic structure(s) are incompletely encapsulated?
Tonsils

Palatine
Pharyngeal
Lingual
How many crypts do each of the following has?

Palatine
Pharyngeal
Lingual
Palatine - many
Pharyngeal - none
Lingual - one
What are the 3 features of tonsils?
Epithelium
CT
Nodules
What is the epithelium of the palatine and lingual tonsils?
Non-keratinized stratified squamous eppithelium
What is the epithelium of pharyngeal tonsil?
Respiratory aka

Psuedostratified columnar with cilia and goblet cell
What lymphatic structure(s) are completely encapsulated?
Lymph nodes
Thymus
Spleen
Fun fact: sinuses direct and slow the flow of lymph through the node
Different types of sinuses:

subscapsular - below CT
trabecular - pierces through the cortex
cortical
medullary - in the medulla
What kind of cells contained in the following parts of the lymph nodes?

Cortex
Paracortex
Cortex - contain lymphocytes that contain B-cells

Paracortex - between cortex and medulla, contains mostly T-cells
How to distinguish medullary sinsuses from medullary cords?
Sinuses - light
Cords - dark
Which section of the lymph nodes has nodule? (medulla or cortex?)
Cortex
What does lymph nodes has that no other lymphatic structure has?
Afferent lymphatic vessels

Everything (including node) has efferent
Fun fact: there are reticular fibers all over the lymph node, especially in the CT capsules
produced by reticular cells

type III collagen
What is the function of thymus?
Site of T-cell education and maturation
Tell me something about the medulla of the thymus
Only one, all medullary areas are connected
What does the cortex of the thymus contain? and where do they come from?
Maturing lymphocytes (t-cell)

Bone marrow, macrophages
What does the medulla of the thymus contain? and where do they come from?
Fewer immunocompetent t-cells and more epithelial reticular cells
What are Hassall's corpuscles in the thymus?
Increase with age, consist of concentrically arranged, flatten, keratinized epithelial reticular cells

Function unknown
What is the function of spleen?
Filter of blood, not of lymph

with only efferent lymphatic vessels

It's important in the removal of microorganisms that invade the circulation and old RBCs and platelets
How is the spleen separated and describe them?
White pulp and red pulp

White pulp - contains secondary nodules, randomly distributed in the spleen, same as other lymphatic tissues

Red pulp - all other areas that surround/between the nodules, also the site where crappy RBCs are pulled from the circulation
What is a central artery surrounded by?
periarteriolar lymphatic sheaths (PALS), a roughly cylindrical aggregation of lymphocytes
What is the oder of the vessels through which blood flows into and out of the spleen?
Arteriole supply:

splenic
trabecular
central
penicillar arterioles
sheathed capillaries
terminal arterial capillaries
splenic sinus
What arteries enter into the red pulp?
penicillar artery
-penicillar arterioles
-sheathed arteriole
-terminal arterial capillary
Fun fact:
Germinal center - B cells
Mantle zone - surrounding center, dark
Marginal zone - surrounding mantle zone
All unique in only spleen

All make up of the white pulp