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33 Cards in this Set
- Front
- Back
- 3rd side (hint)
History
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Unknown; thought to be very ancient
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Epidemiology
stats |
–likelihood of acquiring some strain is 75-90%
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likelihood of acquiring..
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Epidemiology
most common strain in women? |
HPV-16
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Epidemiology
Prevalence of genital warts |
2%
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a percentage
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Etiology
HPV family |
Papovaviridae family - small DNA viruses
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Etiology
Papilloma |
benign growth= wart
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causes...
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Etiology
# of types? |
>140
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Etiology
cause common warts? |
HPV 2, 4, 27, 29
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particular strands
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Etiology
causes plantar warts |
HPV 1
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Etiology
cause flat warts |
HPV 3, 10, 28, 49
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Etiology
Genital strains? |
many
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Etiology
High risk strains |
are found
in cervical and other genital tract cancers |
are found where?
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Etiology
HPV-16, 18, 31, and 45 |
cause 80% of cervical cancer
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cause __ of cervical cancer
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Transmission
vectors: |
shed cells are vectors of transmission
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shed ___
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Transmission
Wound healing |
causes rapid division of basal cells and may increase spread of HPV
Autoinnoculation may occur |
increases ______ and spread of hpv
auto_________ may occur |
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Transmission
Oral transmission? |
possible but not likely
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Transmission
newborns during birth? |
possible
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Transmission
Condoms 100% safe against hpv? |
no. lesions may occur in areas outside condom
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Pathogenesis
Does virus go latent? |
Yes, 1-8 months typically
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Pathogenesis
Process |
Virus in basal cells is replicated rapidly as cells rise to surface; cells at surface filled with viruses; organelles pushed to side
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Virus in ___________ is replicated rapidly as cells ____ to __________; cells at surface filled with viruses; _________ pushed to side
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Pathogenesis
infection continues for ____ months until ________ response diminishes ________ load |
3-6
immune virus |
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Pathogenesis
Host ______ response determines whether disease ________ or _________ |
immune
progresses regresses |
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Pathogenesis
Cancer is |
uncontrolled cell growth
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Pathogenesis
HPV proteins |
fuck up the cells ability to regulate growth or commit suicide if cell is abnormal
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growth and suicide
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Pathogenesis
HPV can hide...how do they? ep______ial |
frequently hides in epithelial cells that are not good at presenting antigens
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epithelial
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Pathogenesis
Invasion of tissue leads to |
transformation of cells
hence bad PAP smear |
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Pathogenesis
Invasive cervical cancer peaks after deep tissue invasion of HPV. Years? |
15 years
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Signs and Symptoms
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Genital warts, condylomas, punched-out cells
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Treatment and Prophylaxis
non genital warts are _________ |
Non genital warts are harmless
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Treatment and Prophylaxis
one way that has been discovered to help remove warts... |
Use of tape
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Treatment and prophylaxis
ways to remove warts |
surgical removal, cryosurgery, laser surgery, chemical treatment
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Treatment and prophylaxis
Genital infection |
–warts and condylomas may be removed; virus may continue indefinitely
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Treatment and prophylaxis
vaccine |
New Gardasil vaccine protects against four strains: 6, 11, 16, 18
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garda_ _ _ against _, _, _, _
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