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26 Cards in this Set
- Front
- Back
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reproductive tract, urinary tract, breasts
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- acute effects of menopause affect these areas of the body
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osteoporosis, cardiovascular disease
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- late effects of menopause
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increased LDL, decreased HDL (hyperlipidemia)
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- effects of menopause on the lipid profile
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estrogen therapy
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- type of therapy that can only be used on women w/o a uterus
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pregnant/breastfeeding
liver disease undiagnosed vaginal bleeding Hx cancer or deep vein thromboses/clotting disorders |
- CI of HRT
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uterine carcinoma
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- unopposed estrogen increases risk; addition of progesterone decreases it
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conjugated equine estrogens (CEE), estradiol
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- natural estrogens
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CEE
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- natural source of estrogen w/o chemical modification
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estradiol
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- natural source of estrogen with chemical modification
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ethinyl estradiol
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- synthetic estrogen
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progesterone
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- natural progestin
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medroxyprogesterone acetate (MPA)
norethidrone acetate (NETA) norgestimate |
- synthetic progestins
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MPA
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- synthetic progestin related to progesterone
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NETA, norgestimate
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- synthetic progestins related to testosterone
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estradiol/NETA (combipatch)
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- the only HRT that doesnt increase triglycerides
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estradiol/norgestimate (ortho-prefest)
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- the only HRT that increases LDL
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ethinyl estradiol/NETA (femhrt)
estradiol/NETA (activella) estradiol/NETA (combipatch) |
- HRTs that decrease HDL
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CEE & MPA
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- HRT combination used in the WHI HRT study
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29% increased risk
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- effect of HRT on CHD
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41% increased risk
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- effect of HRT on stroke
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111% increased risk
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- effect of HRT on VTE
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26% increased risk
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- effect of HRT on invasive breast cancer
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37% decreased risk colorectal
20% decreased risk colon 19% decreased risk rectal |
- effect of HRT on colorectal cancer (colon cancer, rectal cancer)
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34% decreased risk hip
34% decreased risk vertebral 24% less total fractures |
- effects of HRT on fracture - hip, vertebral, total
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hot flashes, sleep disturbances
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- symptoms against which HRT is most effective
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decreased vaginal dryness
decreased heart disease decreased osteoporosis decreased risk of developing Alzheimer's |
- health benefits of HRT
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