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19 Cards in this Set
- Front
- Back
appositional growth in bone |
addition of bone matrix and osteocytes in layers from the periosteum |
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endochondral bone formation |
replacement of cartilaginous model with bone |
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intramembranous bone formation |
bone formation directly from a sheet of connective tissue mesenchyme in embryo periosteum and edosteum in adults flat bones and irregular bones of skull |
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steps in intramembranous bone formation |
1. condensation of mesenchyme 2.vascularization 3. differentiation of osteoblasts 4. secretion of osteoid 5. calcification repeat until bone is formed |
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steps in endochondral bone formation |
1. original hyaline cartilage model 2. bone collar forms around diaphysis 3. bone collar cuts off nutrient supply to cartilage so it dies and the matrix is mineralized 4. periosteal buds invade spaces left by dead chondrocytes in diaphyseal center, carrying in blood vessels and mesenchymal cells that will form osteoblasts and osteoprogenitor cells 5. hemocytoblasts begin forming primary marrow this is all in the primary ossification center
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endochondral bone growth |
cartilage elongates by interstitial growth in the epiphyses new cartilage is replaced by bone has identifiable zones of growth |
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quiescence zone |
region of bone growth of reserve cartilage that contains non-dividing chrondrocytes |
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proliferation zone |
region of bone growth that is actively growing. the chrondrocytes undergo mitosis |
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hypertrophy, calicification, and cell death zone |
region of bone growth in which bone cuts off the nutrient supply, chondrocytes hypertrophy, matrix calificies, and chondrocytes die |
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ossification zone |
region of bone growth in which blood vessels and C.T. invade the empty spaces left by the chrondrocytes, osteoblasts form and secrete osteoid which mineralizes, osteoblasts become osteocytes |
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secondary ossification center |
ossification of the epiphyses works from center out |
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epiphyseal plate |
"growth plate" layer of hyaline cartilage left between the forming bone of the epiphysis and diaphysis replaced by bone at puberty |
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Haversian system formation |
1. parallel blood vessels occupy a shallow groove on the bone surface 2. bone is added in layers along the lateral ridges of the groove until a hollow tunnel is formed 3. inside is covered in osteoblasts that fill the tube outside in |
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zone of ossification |
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intramembranous bone formation |
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bone collar |
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zone of hypertrophy, calcification, and cell death |
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zone of growth |
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zone of quiecsence |