Histology Of The Lymphoid System

Front 1

CD marker of NK cells

Back 1

CD56

Front 2

B cells are derived in these 2 tissues

Back 2

Bone marrow and GALT

Front 3

Main function of B cells

Back 3

Immunoglobulin production

Front 4

CD markers of B cells

Back 4

CD9,19 and others

Front 5

Primary (or central) lymphatic organs

Back 5

Bone marrow
Thymus
GALT

Front 6

Secondary (or peripheral) lymphatic organs

Back 6

Lymph nodes
Tonsils
Spleen

Front 7

Accumulation of the lymphatic tissue which does not have capsule, which is located at the GI (alimentary) canal, respiratory passages and genitourinary tract (lamina propria)

Back 7

MALT (Mucosa-associated lymphatic tissue)

Front 8

Large numbers of plasma cells in MALT indicates

Back 8

Immunoglobulin production

Front 9

Large numbers of eosinophils in MALT indicates

Back 9

chronic inflammation and hypersensitivity reaction

Front 10

Peyer's patches, tonsils and appendix are this type of tissue

Back 10

MALT

Front 11

Diffuse lymphoid tissue in the
wall of GI, GU and RT forms (no germinal centers)

Back 11

Lymphoid Nodules or Lymphatic Follicles (Primary)

Front 12

This has a germinal center (GC), which consists of lymphocyes that have recognized Ag’s and come back to primary follicles with proliferation

Back 12

Secondary lymphatic nodule

Front 13

Light center of the lymphatic nodule consists of

Back 13

Euchromatin
(follicular dendritic cells and macrophages increased after immune response)

Front 14

MZ (mantle zone or corona) of the lymphatic nodule consists of

Back 14

small lymphocytes

Front 15

Forms the lymphatic tissue ring around oropharynx

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Tonsils

Front 16

Types of tonsils

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Pharyngeal, palatine and lingual

Front 17

Tonsils do not have _____ vessels, but they do have lymphatic drainage

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afferent

Front 18

Tonsil epithelium

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Stratified squamous

Front 19

The tonsils are covered by squamous epithelium which dips into the connective tissue, which forms

Back 19

Tonsillar crypts

Front 20

Peyer’s patches are located in the

Back 20

Ileum

Front 21

Peyer's patches consist of aggregations of lymphatic nodules containing both of these cells

Back 21

T and B lymphocytes

Front 22

This layer in the intestines is densely infiltrated by lymphocytes and contains multiple follicles

Back 22

Lamina propria

Front 23

Encapsulated organs located along the pathway of lymphatic vessels and serve as filter for lymph

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Lymph Nodes

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Superficial cortex of the lymph nodes consist of

Back 24

Primary and secondary nodules

Front 25

Deep cortex (paracortex) of the lymph nodes consist these cells

Back 25

T lymphocytes

Front 26

Medullary cords of the lymph nodes consist of

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B lymphocytes

Front 27

Capsule and trabeculae of the lymph node consist of

Back 27

Dense connective tissue

Front 28

Lymph nodules of the lymph nodes consist of

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B lymphocytes

Front 29

Serves as the entrance to the lymph node for circulating lymphocytes

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HEV (high endothelial venules; 90% of lymphocytes enter through this route)

Front 30

Circulating lymphocytes enter this layer of the lymph node (via HEV)

Back 30

Deep cortex

Front 31

Put in order of flow in the lymph node : medullary sinuses; trabecular sinuses; subcapsular sinuses

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1. Subcapsular
2. Trabecular
3. Medullary

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Reticular cells of the lymph node synthesize and secrete this type of collagen

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Type III

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Location of follicular dendritic cells

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Germinal centers of the lymph nodes (Distributed between B-cells)

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Function of follicular dendritic cells

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Bind to Ab-Ag complexes; they are not APC's

Front 35

Cortex of the thymus consist of closely packed

Back 35

T lymphocytes

Front 36

Dense accumulation of the
lymphcytes surrounding
blood vessels in the spleen

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White pulp (PALS)

Front 37

Layers of the epidermis that Langerhans' cells are only found

Back 37

The middle layers of epidermis

Front 38

Lymphatic and hematopoietic tissue cells possess these unique cell surface molecules named by an international system that relates them at different stages of their differentiation

Back 38

CD molecules (cluster of differentiation)

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CD2

Back 39

Clinical marker for T cells

Front 40

CD molecule that's elevated in chronic lymphocytic leukemia

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CD5

Front 41

Clinical marker for T-cell leukemia (CD molecule)

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CD7

Front 42

Common marker (CD molecule) for acute lymphoblastic leuemia

Back 42

CD10

Front 43

Clinical marker (CD molecule) for all stages of B-cell development

Back 43

CD19

Front 44

CD34

Back 44

Clinical marker for pluripotential stem cells in bone marrow

Front 45

CD38

Back 45

Marker for T-cell activation

Front 46

CD56 and CD94

Back 46

Clinical Marker for NK cells

Front 47

Helper T cells that synthesize IL-2, IFN-gamma and TNF-alpha are called

Back 47

Th1 cells