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20 Cards in this Set

  • Front
  • Back
what do myofibroblasts do
participate in wound healing
what do brown adipose cells have that normal ones don't
many lipid droplets (multilocular)

a central nucleus

many mitochondria

increased innervation and vascularization of the tissue
where do mast cells originate and differentiate
They start out in the marrow from cells lacking cytoplasmic granules and differentiate on site, in the connective tissue where they wind up
what is the most abundant type of collagen
Type I
what are the 4 main amino acid components of collagen
glycine, proline, hydroxyproline, hydroxylysine
collagen bits spit out of fibrocytes are called

enzymes clean up the end and they're called
procollagen

tropocollagen
lots of tropocollagen bits line up in a very orderly way to make a
collagen fibril
side by side crosslinking of collagen fibrils forms
a collagen fiber
what type collagen:

bone, tendon, dentin and skin

provides tensile strength
Type I
what type collagen:

reticular lamina of basement membrane, component of reticular fibers
Type III
what type collagen:

basal lamina

each molecule binds to binding sites of lamina
Type IV
what type collagen:

Hyaline and elastic cartilage

observed as fibrils
Type II
what type collagen:

Amnion and Chorion in the fetus, muscle and tendon sheaths.

Does not form banded fibrils
Type V
what is the first type of collagen synthesized during wound healing
Type III reticular
the three developmental stages of elastic fibers
oxytalan

elaunin

elastic elastic fibers require a special stain
is there hydroxyproline in elastic fibers?

what is a major protein component of them?
No

Fibrillin

elastin stretches and relaxes, forming a different random coil each time
what are dermatan sulfate
chondroitin sulfate
keratan sulfate
heparan sulfate

what do they look like in action?
glycosaminoglycans

they are the brushes on the bottle brush
what are fibronectin, laminin, chondronectin
the adhesion molecules of glycoproteins
what is a proteoglycan
a great long fiber of hyaluronane, woven among the collagen fibers, with bottle brushes down it's length, glycosaminoglycans on core proteins
what are the two components of ground substance
glycoproteins and glycosaminoglycans