Histology- Cardiovascular

Front 1

What is an intercalated disk?

Back 1

Consists of fascia adherens, desmosomes, and gap jxns.

Front 2

Continuous Capillaries:

Back 2

Most frequent
present in skeletal muscle, connectice tissue, lung, brain

Uninterrupted barrier to macromolecules

Front 3

Describe Cardiac Myocytes

Back 3

1)Contract through intrinsic action potentials that are passed to neighbors via GAP JXN
2)Contain a Diad which is a T-tubule flanked by one terminal cisterna
3) Intercalated disks

Front 4

Describe the adventitia (3)

Back 4

1) Fibroblasts
2) Type I collagen
3) Some elastic fibers

Front 5

What does epicardium consist of?

Back 5

Connective tissue and a layer of mesothelium. (Visceral layer of the pericardial sac)

Front 6

Arterioles are different in tunica media why?

Back 6

1)The tunica media consists of only 1 -2 layers of smooth muscle cell.
2)Plays a major role in reg. blood pressure.

Front 7

Are purkinje myocytes neurons?

Back 7

NO, they arejust modified myocytes

Front 8

Describe the intima. (4)

Back 8

1)Consists of endothelium,
2)basal lamina,
3)loose connective tissue,
4)internal elastic membrane

Front 9

What is endocardium lined with?

Back 9

Endothelium on top of subendocardial layer that is continuous with the tunica intima of blood vessels

Front 10

What makes muscular arteries different?

Back 10

Tunica intima with a PROMINENT internal elastic lamina and a tunica media with a PROMINENT smooth muscle cell component

Front 11

Can cardiac muscle be repaired?

Back 11

No, the muscles cannot regenerate, but the injury is usually replaced with connective tissue.

Front 12

Lymphatic Vessels:

Back 12

Lymph capillaries are blind ended and resemble sinusoids.

They may show three distinct TUNICS.

Have many closely spaced valves.

Front 13

What is in the subendocardial later?

Back 13

Blood vessels, nerves and purkinje fibers.

Front 14

Capillaries

Back 14

Tubes of endothelium reinforced by a basal lamina. Cross sectional area is 800 times that of aorta. Site of exchange of nutrients.

1) continuous
2) fenestrated
3) sinusoidal

Front 15

What are the three tunics of blood vessels (b.v)?

Back 15

Tunica intima
Tunica media
Tunica adventitia

Front 16

Describe the media (4)

Back 16

1)smooth muscle cells
2)Type III collagen
3)Elastic fibers
4)external elastic lamina

Front 17

Large Veins:

Back 17

SUPERIOR/INFERIOR VC
I: thicker with scattered bundles of longitudinal SM (Internal elastic membrane?)
M: Thin lacks SM
A: THICKEST with connective tissue and longitudinal SM

Front 18

Venules:

Back 18

Intima: only an endothelium
Media: Thin (1-2 layers of muscle, few elastic fibers
Adventitia: Slightly thicker than media and made of longitudinally arranged collage fibers

Front 19

Sinusoidal Capillaries:

Back 19

Gaps are present between endothelial cells allowing passage of large molecules and cells
LIVER, SPLEEN

Front 20

What makes Elastic Arteries so great?

Back 20

Have tunica media with a prominent elastic fiber component that responds to the high systolic pressure

Front 21

Fenestrated capillaries:

Back 21

Endothelial cells are perforated by pores. These holes allow very large molecules to cross the endothelium

Front 22

Small to medium veins:

Back 22

Intima: endo alone, or together with elastic fibers and bundles of longitudinal smooth muscle
Media: Thin --alternating plates of SM and networks of collagen and elastic fibers
Adventitia: well developed fibroelastic coat

Front 23

How do you identify a vein?

Back 23

It is with an accompanying artery.