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82 Cards in this Set

  • Front
  • Back

What FOUR types of CELLS are in LYMPHATICS?

FIBROBLASTS


RETICULAR CELLS (Diff'd Fibroblasts)


ANTIGEN PRESENTING CELLS (Macrophages)


LYMPHOCYTES

What type of COLLAGEN do RETICULAR CELLS make?

TYPE 3 COLLAGEN




(RETICULAR FIBERS)

What type of FIBERS do RETICULAR CELLS make, via TYPE 3 COLLAGEN?

RETICULAR FIBERS

What is the FUNCTION of ANTIGEN PRESENTING CELLS in LYMPHATICS?

ANTIGEN PRESENTING CELLS

What TYPE of cell are ANTIGEN PRESENTING CELLS?

MACROPHAGES

What are the TWO types of LYMPHOCYTES?

B-CELLS


T-CELLS



What TYPE of COLLAGEN do FIBROBLASTS produce?

TYPE 1

What is the FUNCTION of B-CELLS

DIFFERENTIATE into PLASMA CELLS

Describe the DIFFUSE ORGANIZATION of LYMPHOCUTES

LYMPHOCYTES are HAPHAZARDLY arranged AROUND TUBE STRUCTURES




"spread-out around tubes"

What does MALT stand for?

MUCOSA ASSOCIATED LYMPH TISSUE




In contact w/outside world

Describe a NODULE

SPHERICAL AGGREGATION of LYMPHOCYTES

What are the TWO REGIONS of a NODULE?

CORTEX




GERMINAL CENTER

Are ACTIVATED or UNACTIVED LYMPHOCYTES located in the NODULE CORTEX?

UNACTIVATED




(mostly Nucleus)

Are ACTIVATED or UNACTIVED LYMPHOCYTES located in the GERMINAL CENTER?

ACTIVATED




(more Cytoplasm)

What is a NON-ENCAPSULATED aggregation of NODULES?

PEYER'S PATCHES

Define PEYER'S PATCHES

COLLECTION of <200 NODULES

Where are PEYER'S PATCHES FOUND?

ILIUM

Why is are PEYER'S PATCHES termed NON-ENCAPSULATED?

NOT COVERED by C.T.

Describe PARTIALLY ENCAPSULATED NODULES

NODULES

Where do TONSIL ARISE from?

WALDEYER'S RING

What/Where is WALDEYER'S RING

RING of LYMPHATIC TISSUE around the BACK OF THROAT

What are the THREE COMPONENETS of WALDEYER'S RING?

PALATINE


LINGUAL


PHARYNGEAL

Describe PALATINE TONSILS

ENCAPSULATED collection of NODULES around the SIDES OF THROAT

Describe LINGUAL TONSILS

NON-ENCAPSULATED collection of NODULES in the BASE OF TONGUE

Describe PHARYNGEAL TONSILS

ENCAPSULATED collection of NODULES on ROOF of PHARYNX

What is an INFECTION of the PHARYNGEAL TONSILS?

ADENOID

What is an ADENOID?

SWELLING of the PHARYNGEAL TONSILS

What is MEANT by ENCAPSULATED

COVERING of CONNECTIVE TISSUE

What kind of EPITHELIUM COVERS the PALATINE & LINGUAL TONSILS?

STRATIFIED SQUAMOUS

What kind of EPITHELIUM COVERS the PHARYNGEAL TONSILS?

PSEUDOSTRATIFIED

What is a NODE?

Bean shaped ORGAN

(very different from a nodule)


What is the general STRUCTURE of LYMPH NODES?

BEAN SHAPED




Occur in CLUSTERS (grapes)

How does LYMPH NODE SWELLING occur when sick?

LYMPHOCYTES becomes ACTIVATED ->


INCREASES GERMINAL CENTER SIZE ->


INCREASE IN LYMPH NODE SIZE

What is the PRIMARY FUNCTION of LYMPH NODES?

To FILTER LYMPH


Describe the PATHWAY of LYMPH FILTRATION in LYMPH NODES

AFFERENT LYMPHATIC VESSELS ->


AFFERENT V. PIERCE CAPSULE ->


DUMPS INTO SUBCAPSULAR SINUS->


LYMPH NODULES (in CORTEX) ->


PARACORTEX (T-Cells) ->


CORDS & SINUSES ->


EFFERENT



What is the LYMPH NODE CAPSULE made of?

CONNECTIVE TISSUE

How do the AFFERENT VESSELS Connect to the LYMPH NODE?

By PIERCING the CAPSULE (C.T.)

Define the TRABECHULAE

Where C.T. is DRAGGED IN by AFFERENT VESSELS




SUBDIVIDES the LYMPH NODE

Where are LYMPH NODULES LOCATED in the LYMPH NODES?

OUTER PORTION of the NODE




ie. CORTEX

Where is the CORTEX of the LYMPH NODE?

OUTER REGION

Describe the PARACORTEX

DENSE COLLECTION of LYMPHOCYTES




BELOW the CORTEX




w/T-CELLS

Where are T-CELLS LOCATED in the LYMPH NODES?

PARACORTEX

MEDULLA

SINUSOIDS




CORDS

Describe a CORD

COLLECTION of MACROPHAGES, FIBROBLASTS, & COLLAGEN

Describe a SINUSOID

LOOSE MEANDERING SPACES




(floppy capillaries)

Define the SUBCAPSULAR SINUS

Space ABOVE NODULES in LYMPH NODE

What are the THREE FUNCTIONS of LYMPH NODES?

BIOLOGICAL FILTER (Macrophages)


PHYSICAL FILTER


ANTIBODY PRODUCTION

Are B-CELLS found in the THYMUS?

NO

Are T-CELLS found in the THYMUS?

YES

Where is the THYMUS located in the BODY?

BEHIND the STERNUM

What is the THYMUS ENCAPSULATED BY?

CONNECTIVE TISSUE

How is the THYMUS organized?

Into TWO IDENTICAL LOBES

How are the LOBES of the THYMUS SUBDIVIDED?

LOBULES via C.T. of TRABECULAE

How is the THYMUS LOBULES ORGANIZED?

MEDULLA: Inner Portion


CORTEX: Outer Portion

What kind of CORPUSCLE is found in the MEDULLA of the THYMUS

HASSEL'S CORPUSCLES

Describe HASSEL's CORPUSCLES

SPHERICAL Aggregation of EPITHELIAL CELLS in the MEDULA




(unknown function)

What is the EPITHELIO-RETICULAR FRAMEWORK?

Long/Thin EPITHELIAL cells that FORM FRAMEWORK of THYMUS

What KIND of CELLS are FOUND in the THYMUS?

T-CELLS!


What is the FUNCTION of the SPLEEN?

FILTER RBCs


Where is the SPLEEN LOCATED?

UNDERneath the DIAPHRAGM

How does the SPLENIC ARTERY enter the SPLEEN?

BRANCHES & PIERCES THRU the CAPSULE




(Arberization)

Define a TRABECULAR ARTERY

COVERED in C.T. from CAPSULE PIERCING




ie. C.T. Sheath

Define a CENTRAL ARTERY

C.T. is GONE and is COVERED by LYMPHOCYTES




(Technically an Arteriole)

Define PENICILLAR ARTERIES

Very STRAIGHT arteries




BRANCHED from Central Arteries




(Like many Peninsulas)

Describe the PATHWAY of BLOOD Thru the SPLEEN

SPLENIC ARTERY ->


TRABECULAR ARTERY ->


CENTRAL ARTERY ->


PENECILLAR ARTERY ->


CORDS & SINUSES

What are the CORDS of the SPLEEN CALLED?

CORDS OF BILLROTH


What are the CORDS OF BILLROTH composed of?

LYMPHOCYTES


MACROPHAGES


RETICULAR FIBERS

What are the WHITE AREAS of the SPLEEN?

WHITE PULP

What is WHITE PULP made of?

LYMPHOCYTES & CENTRAL ARTERIES (WBC)

What is RED PULP made of?

CORDS & SINUSES (RBC)

What are the THREE FUNCTIONS of the SPLEEN?

RBC FILTER


PLATELET STORAGE


ANTIBODIES (via B-CELLS)

How does the SPLEEN FILTER RBCs?

MO ENGULFS RBC ->




Fe+ sent to BONE MARROW




Heme broken into Biliruben (Br) ->


Br dumped to BLOOD & attached to Albumin->


Liver removes Br & attaches it to 2x GA Molecules (Conjugated Biliruben)->


Poop

Describe PLATELET STORAGE of the SPLEEN

SPLEEN CAPSULE may contract to SQUEEZE 30-40mL of PLATELET rich blood into BVs

What type of LYMPHOCYTE is found in the THYMUS?

ONLY T-CELLS

What is the FUNCTION of the THYMUS?

T-CELL "EDUCATION"

How many LOBES make up the THYMUS?

TWO IDENTICAL lobes

What is the FIRST lymphatic organ FORMED?

THYMUS

What is special about the FRAMEWORK of the THYMUS?

Made of an EPITHELIO-RETICULAR FRAMEWORK

What is meant by the EPITHELIO-RETICULAR FRAMEWORK of the THYMUS?

LONG/THIN EPITHELIAL framework

What are HASSELL'S CORPUSCLES and WHERE are they found?

MEDULLA of the THYMUS LOBULES




SPHERICAL AGGREGATIONS of EPITHELIAL CELLS




Don't know what they do (It's a HASSLE)

Where is the THYMUS located?

Behind the STERNUM