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26 Cards in this Set

  • Front
  • Back
1. What are the 3 types of cartilage?
2. whats type of collagen present
3. which ones have a perichondrium
1. Hyaline, elastic, fibrocart

2. H/E = type II
Fibrocart = Type I
3. Hyaline/elastic
What are the locations of cartilage
A. Hyaline
B. Elastic
C. fibrocartilage
1. Temporary skeleton, Epi plate, articular surfaces, respiratory passages

2. Auricle (ear), aditory tube, epiglottis, cuneiform ligament
3. IVD, ligs, pubic symph, tendon insertions (always assoc. w/ dense c.t
Chondrocyte arrangement
1. hyaline
2. elastic
3. fibrocart
1. isogenous groups/single
2. same as hyaline
3. Long columns
How can cartilage grow, compare that to bone
1. Interstitial: mitotic divisions of chondrocytes (early). Appositional: diff of perichondrial cells.

Bone only by appositional
Give the name of cells and location
1. Cartilage
2. Bone
1. Chondrocytes: lacunae
2. Osteocytes: lacunae
In general what does the matrix of cartilage contain
2. what else does elastic cart contain
1. collagen, hyaluronic acid, proteoglycans, glycoproteins

2. Elastin fibers
Identify nutrition
1. Cartilage
2. Epithelium
3. Bone
4. Nerve
1. Avascular: diffusion via perichondrium
2. Avascualr: diff (BM)
3 Vascular: Haver canal (volkmans)
4. Poorly vascularized: epineurium/perinuerium; endo = poor
Mesenchyme gives rise to
1. Chondroblasts
2. Osteoprogenitor (then blast)
3. Fibroblast
What are the divisions of Connective tissue
1. Embryonic (mesen/mucous)
2. Adult proper: LARD
3. Specialized: BBC
What are the 2 general classes of CT proper cells
Fixed, wandering
What are the features of plasma cell
1. structure
2. derived from
1. clock face/eccentric nuc, juxtanuclear golgi
2. mesoderm (B-lymphocyte)
What fibers are seen in CTs
1. Collagen, Elastic, Reticular
What is the scheme of collagen organization (polymerization)

2. where does it occur
tropo -- fibril --fibers--bundles
What are the types of collagen fibers
1, 2, 3, 4, 5, 7, 10
Type of collagen and cells of origin.
1. Hyaline/elastic
2. CT stoma
3. Anchoring fibrls
4. Zone of hypertrophy
1. II, chondrocytes
2. 5, fibroblast, Reticular, S.M muscle
3. 7, Fibroblasts
4. 10,Chondrocytes
What is the major type of collagen fiber present in CT

2. Where is it located
1. Type I
2. L and DORCT, tendon, ligs, fascia, fibrocart, bONE, Dentin
What are the types of components in GS
1. GAGs (sulfated, nonsulfated)
2. Glycoproteins: fibronectin, laminin, inter w/ integrin
3. MMPs (degrades ECM in Ovulation)
Location of CT proper: LARD
1. Loose and DIRCT
3. Reticular
4. Adipose
1. Dermis, submucosa
2. Tendons, aponeurosis, submucosa
4. hypoderm,around organs, orbit, w/in mitochondria
6 in 06
1. Duputren disease
2. Osteogenic imperfecta
3. Mafrans
4. Ehlers-danlos
5. Alport
1. myofibroblast disorder
2. brittle bone, blue sclera
3. CT disorder; no/or irreg fibrillin (myofibril)
4. Type III col deficency, in BV and organ walls
5. Type IV defect, basement mem disorder
1. What is lipoma
2. where is it found
1. common benign adipose tissue tumor
2. Sub-Q of back,thorax and prox upp/low limbs
1. What are the general components of CT matrix

2. Do all CT have same funx
1.fibers, GS, tissue fluid
2. No, varies by type
1. What is mesenchyme
2. what does it give rise to
primitive CT in early embryo

2. Adult CTs, muscle, vascular/urogenital systems, L nodes, Spln, BC, Synovium, Serous membranes
1. what is mucous CT
2. where can you find it
3. how are cells
1. Whartons jelly, gelatin like GS
2. in umbilical cord and tooth pulp
3. ovoid or stellate shape
1. What is Adipose classifed as
2. What are 2 types
3. What type is present in Adults, fetal life
1. Specialized CT
2. White; unilocular (fat), Brown:multilocular (ENG)
3. Adult = white, Fetal = brown (brown diminishes w/ age)
What are the INTRAcellular events in collagen formation
In rER
1. Uptake AA (gly,pro,lys)
2. Synth of alpha chains by ribosomes
3. Hydroxylation of Pro,Lys (vt C requ)
4. Glycolysation
5. Form procollagen triple helix and moves to transer vessicle
outside rER
1. Golgi packages
2. move vessicles to PM (mfs,Mts
3. Exocytosis of procollagen
CT cells
2. Wandering
1. Fibroblast, myofibroblast, macs, Adipocytes, Mast cells, Undiferentiad mesenchyme (pericytes.

2. Lymphocytees, PCs, Neut, Eosin,Baso,Monocytes