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12 Cards in this Set
- Front
- Back
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Muscle tissue types
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Skeletal muscle fibers-strong, quick, voluntary, banding pattern, actin/myosin (sliding filament theory), organization(epi/peri/endo-mysium)
Cardiac-strong, quick, continuours, involuntary, similar contractile, diff cell-geometry and organization smooth muscle-weak, slow, involuntary, actin/myosin in non-ordered arrays, diff org/method of contraction |
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Skeletal muscle cell Membrane
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-outer membrane-indentations (T tubules)
-whole plasma membrane covered with basement membrane -satellite cells-under the basement membranes = PROGENITOR CELLS-if muscle cell dies, progenitor cell grow->new cell -DYSTROPHIN molecule link cells together; defects = muscular dystrophy (MD) |
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()-mysiums
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endomysium-seperates muscle fibers
perimysium-wraps bundles of muscle fibers epimysium-covers muscle |
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skeletal muscle cells
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-every skeletal muscle cell has one nerve cell
-multinucleated b/c they are composed of several cells, coupled together to form a SYNCYTIU -calcium source = sarcoplasmic reticulum |
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mito
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-spots seperating banding muscle fibers
-dark area=nucleus |
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sarcomere
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z-z=sarcomere
a-band (DARK) thick, H in middle I-band (LIGHT) thin, zin middle |
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contraction
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actin, topomyosin, troponin-all coiled together
troponin-3 subunits (Tnc is important), covers binding site for myosin head on actin fil. Until Ca binds Tn-c. A-band doesn't change H,I,total sarcomere change. |
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NMJ
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nerve may attach at only one point, but signal will spread to whole muscle
Two ACh molecules to one receptor to open it |
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know diff b/w dark and light muscle
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book
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Cardiac Muscle
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-nucleus in central sarcoplasm
-intercalated disks-connect cardiac muscle cells, dark lines, perpendicular to the long axis -myofibrils-less well-organized than skeletal muscle cells -distinguish single cardiac myocytes -sarcoplasmic reticulum-less extensive, Ca2+ comes from extracell space, T tubule membranes, and SR |
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cardiac pictures
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fascia adherens-binding site for actin (FA+desmosome transmit cell from one force to next
***Cardiac muscle cell have gap jxn's, skeletal do not |
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smooth muscle
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-spindle-shaped cells
-gap junctions CONTRACTION: -inact.=coiled myosin, act.=atp uncoils myosin->contraction, myosin not ancord -dense bodies connect contractile filaments, which are attached to the walls of the cell inside, the cell twists when it contracts |
