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8 Cards in this Set

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  • Back
What is the basic reproductive number?
expected number of secondary cases generated by a primary case in an entirely susceptible population
How is the basic reproductive number interpreted?
R >1 implies that it will spread
R< 1 implies the infection will die out and not be able to propagate
What is the effective reproductive number?
average number of secondary cases attributable to a single case of infection
- NOT in an entirely susceptible population
How does the effective reproductive number compare to the basic reproductive number?
R= R0(x) where x is the susceptible fraction of the population
It will be smaller because the population is not entirely susceptible
How does the susceptible fraction change over time in an outbreak?
it will decrease as animals either die or recover and gain immunity
What factors affect the effective reproductive number?
infectiousness of the agent
number of adequate contacts in the time period
duration of the infectious period
presence of susceptible animals
How does vaccination effect the effective reproductive number?
It will decrease the effective reproductive number because fewer individuals in the population will be susceptible to infection
What percentage of the population must be vaccinated to generate herd immunity?
1-1/Ro

This is often >90%