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11 Cards in this Set
- Front
- Back
Is an acute hep B illness that bad?
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No, can even be asymptomatic.
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Then why is Hep B virus so bad?
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It persists in 5-10% of immunocompetent people, and causes cirrhosis and hepatocellular carcinoma.
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What causes the pathologic effect of HBV?
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The host's immune response to the persistant virus infected hepatocytes.
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What is HBe Ag?
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A soluble antigen secreted by infected hepatocytes.
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What is HBs Ag?
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The surface antigen of HBV.
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What is a good indication that a person's immune system has cleared the virus?
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Seroconversion of HBeAg to Anti-HBe.
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What are the 3 antigens detected in HBV?
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Hep B Surface
Hep B Core - its ANTIBODY Hep B e |
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Which HBV antigens appear first in infection, and when?
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HBs and HBe Ag; during incubation, 2-8 weeks before any other change occurs.
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How long is HBsAg detectable?
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Through acute phase, clears by convalescence. Usually only 2-6 weeks.
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Which antigen is detectable after HBsAg?
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ANTI-HepBc
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What is a valuable use of Anti-HBc?
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-It is a lifelong marker of infection with HBV (as IgG)
-Important marker of recent acute infection, esp if HBs and HBe antigens are neg. |