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4 Cards in this Set
- Front
- Back
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Normal Hemoglobin in RBCs
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-Hemoglobin A
-Hemoglobin A2 -Fetal Hemoglobin |
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Major Gene Clusters of Hemoglobin
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-B Locus on Chromosome 11
-a Locus on Chromosome 16 |
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Sickle Cell Disease (SCD)
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-Severe hemolytic anemia characterized by a RBCs abnormally shaped under stress
-Heterozygous = protection from malarial infection -Homozygous = premature death |
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SCD- Substitution in __ codon of __ gene
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-Substitution in 6th codon in B gene
-Glutamic acid replaced by Valine |
