Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/9

Click to flip

9 Cards in this Set

  • Front
  • Back
What causes sickling?
because Hb C has same gel electro pattern as HbA2 (and HbE)
What causes sickling?
deoxygenation causes polymerization of HbS
What factors are protective for leg ulcers in sickle cell dz?
alpha deletion, increased Hb, increased HbF
What are risk factors for leg uclers in sickle cell dz?
male sex, age
Which is worse…HbH or HbBarts?
Hb Barts causes intrauterine death
How do HbH and HbBarts hurt you?
HbH (gets oxidized and forms inclusions that lead to hemolytic anemia) HbBarts (wont let go of oxygen)
Neurologic complications in SCD?
cerebral infarct (kids) cerebral hemorrhage (adults)
Tx for cerebral infarct in a kid w/SCD?
exchange or hypertransfusion to maintain HbS<%30
Why seizures in SCD?
focus due to infarct; meperidine tx for pain; idiopathic