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45 Cards in this Set

  • Front
  • Back
What two factors determine blood flow?
Pressure/resistance
What drives blood flow?
Pressure
What impedes blood flow?
resistance
What is the most important factor in resistance in the vessels?
The radius or diameter of the blood vessel; inversely proportional to the 4th power
What does laminar flow describe?
The fact that blood velocity is greater at the center of teh vessel than along the outer edges
What is the main regulator of blood vessel diameter?
Autonomic nervous system
What percentage of blood volume can be found in the systemic system at any given time?
79%
What percentage of blood volume can be found in the pulmonary circuit at any given time?
12%
What percentage of blood volume can be found in the heart at any given time?
9%
What is the breakdown within the systemic system for blood percentages?
15% arteries
5% capillaries
59% veins
What is the average blood pressure in large arteries?
100-95
What is the average blood pressure in small arteries?
95-85
What is the average blood pressure in arterioles? ***
85-30 (important in regulation)
What is the average blood pressure in capillaries?
30-10
What is the average blood pressure in veins?
10-0
Under what principle do precapillary sphincters work?
Autoregulation; open and close due to varying amounts of O2, CO2, and H+
What causes the osmotic force in capillaries?
Albumin
How do you calculate pulse pressure?
Systolic - Diastolic
What is Edema?
The presence of excess interstitial fluid in the tissues
What are the 3 main causes of edema?
1. Increased capillary hydrostatic pressure
2. Decreased plasma protein
3. increased interstitial fluid protein
What three things can change blood pressure?
1. Cardiac output
2. Peripheral resistance
3. Total blood Volume
What controls long term regulation of blood pressure?
Hormones
What does ADH stand for and what does it do?
ADH is Anti-Diuretic Hormone, it decreases urinary output. It can take up to 30 minutes to work
What is Primary aldosteronism (Conn's Syndrome)?
A tumor grows in the adrenal cortex, causing an overabundance of aldosterone to be secreted, thusleading to hypertension, increased extracellular fluid volume, hypernatremia, and potassium depetion.
What controls short term regulation of blood pressure?
Nervous system, it reacts within seconds or minutes.
What are the two major control mechanisms for short term regulation of blood pressure?
Baroreceptors and chemoreceptors.
Where is the control center for blood pressure in the brain?
medulla
What are the two parts of the control center for blood pressure?
Cardioinhibitory center
vasomotor center
What does stimulation of the Cardioinhibitory center correspond to and what does it do?
It corresponds to parasympathetic stimulation, it decreases HR, CO, and increases vasodilation, thus decreasing blood pressure
What does stimulation of the vasomotor center correspond to and what does it do?
Sympathetic stimulation, it increases HR, CO, and vasoconstriction, thus increasing Blood Pressure
Baroreceptors stimulate what kind of response?
Baroreceptors stimulate the cardioinhibitory center and inhibit the vasomotor center. (parasympathetic, release ACH)
Chemoreceptors stimulate what kind of response?
Chemoreceptors only stimulate the vasomotor center (sympathetic release Norepinephrine)
What causes circulatory shock?
inadequate blood flow and/or oxygen delivered to tissues
What are the four main types of circulatory shock?
Hypovolemic
Anaphylactic
Neurogenic
Cardiogenic
What is Hypovolemic shock?
Low volume of blood, either loss of blood from hemhorrhaging, dehydration, or loss of fluids from burns
What is Anaphylactic shock?
Drop in blood pressure do to severe allergic reactions, causing high amounts of histamine to be released. (Histamine is a vasodilator)
What is Neurogenic shock?
Spinal cord damage which causes decreased sympathetic activity
What is Cardiogenic shock?
Inadequate circulation of blood due to heart failure
What is hypertension?
high blood pressure
What percent of all deaths are related to hypertension?
12%
How does hypertension cause death?
By rupturing a vessel in a vital organ or by causing the heart or kidneys to fail
What are the characteristics of primary hypertension?
No cause can be determined
85-90% of hypertensive patient
rare if you're under 20
usually occurs 25-50 years
more frequent in females
genetic
blacks more than whites
high salt intake can contribute
stress may play a role
What are the characteristics of secondary hypertension?
Has clearly definable causes
10-15% of population
What are symptoms of Essential hypertension?
Headache (often in the morning), dizziness, fatigue, blurring of vision, polyuria, polydipsia, muscle weakness, hypokalemia.
How do you treat hypertension?
Exercise
weight loss
low carb diet
stop smoking
less salt
reduce stress