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24 Cards in this Set
- Front
- Back
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RBC membrane transporter in chloride shift
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Cl-/HCO3- exchanger
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Anisocytosis
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Varying SIZES
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Poikilocytosis
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Varying SHAPES
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Platelet granules
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Dense granule: ADP, calcium
alpha granules: vWF, fibrinogen |
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Where are platelets stored?
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Spleen
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Neutrophil levels elevated in
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Bacterial infections
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Neutrophil appearance in B12/folate deficiency
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Hypersegmented nuclei
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Increased neutrophil band cells in which conditions?
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Increased myeloid proliferation (bacterial infection, CML)
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Monocyte appearance
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Kidney-shaped nucleus with "frosted glass" cytoplasm
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Macrophage activated by
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gamma-interferon (Th1 cell release)
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Macrophage cell surface marker
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CD14
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Eosinophil levels increased by
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Helminthic infections
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Eosinophil regulate allergic response by producing
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Histaminase and arylsulfatase
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Causes of eosinphilia (NAACP)
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Neoplasm
Asthma Allergen Collagen vascular disease Parasites |
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Basophil
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Allergic reactions; histamine, heparin, leukotriene
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Mast cell
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Allergic reaction; resembles basophils; bind Fc portion of IgE
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Drug used to prevent mast cell degranulation
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Cromyolyn sodium
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Dendritic cell surface receptors
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MHC class II, Fc receptor
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Dendritic cells in skin
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Langerhans cells
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B lymphocyte surface receptors
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CD19, CD 20
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Plasma cell appearance
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Off-centre nucleus, clock-face chromatin, abundant RER, Golgi
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Cytotoxic T cell surface rceptors
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MHC class I, CD 8
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Helper T cell surface receptors
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MHC class II, CD4
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Costimulatory signal for T-cell activation
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CD28
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