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16 Cards in this Set

  • Front
  • Back
pt with hx of lymphoma cancer px with symptoms of lower spinal compression. next step?
epidural spinal cord compression
- lymphoma's are radiation sensitive -> high dose steroids and radiation
pt with small cell lung cancer px with sx of spinal compression. Tx?
surgical resection as is resistant to radiation
lobular carcinoma in situ (LCIS) of breast. tx? sentinel node biopsy? prognosis? post treatment?
excisional biopsy
- sentinel node biopsy not needed as has no metastasis risk.
- can progress to DCIS or invasive cancer
- close monitoring
pt develops HIT on warfair and unfractionated heparin. Next step
d/c both warfarin and heparin and start direct thrombin inhibitors (e.g. lepiruin or argatroban)
difficulty cross matching blood in pt with multiple transfusions in past. why?
alloantibodies
pt with prostate cancer resistant to hormone therapy has bone mets. How do you relieve the pain?
external beam radiation therapy
what is the most common cause of hereditary thrombophilia
factor V deficiency
asymptomatic pt on tamoxifen. What are they at increased risk for? What screening do they need? What if they have abnormal bleeding or other sx?
endometrial cancer
- pap
- TVUS or endometrial biopsy
how much does a unit of platelets raise platelet count? When do you measure? What should you think if the rise is too low?
5k
- 10-60minutes after transfusion
- alloimunization
elderly with bone pain, hypercalcemia, and renal dysfunction. Think? work up
multiple myeloma
1)- serum protein electrophoresis
2) skeletal survey with x-ray - NOT bone scan
3. bone marrow biopsy
** pt with multiple myeloma or Waldenstrom's macroglobulinemia px with headache, dizziness, vertigo, nystagmus, hearing loss, and visual impairment. Think?
hyperviscosity syndrome 2/2 high protein content
chronic methotrexate inducing macrocytic anemia. Tx?
folinic acid (Leucovorin)
pt has bcr/abl translocation. dx? chromosome? tx?
chronic myeloid leukemia 9,22
- tyrosine kinase inhibitor regulation destroyed.
how do you prevent a febrile transfusion reaction
wash cells of leukocytes
squamous cell carcinoma of skin. 1st line tx, 2nd?
surgery
radiation
multiple brain mets. what improves survival?
whole brain radiation