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51 Cards in this Set
- Front
- Back
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In terms of ABO blood group system, the ___ gene produces a substance (___ substance) on which the ABO gene products act.
Which of the following is the "A" gene product? a. 1,3-N acetylgalactosaminyl transferase b. 1,3-galactosyl transferase c. gene product produces a serum protein product that has no known enzymatic activity |
H, H
A. |
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"O" gene product produces:
a. 1,3-N acetylgalactosaminyl transferase b. 1,3-galactosyl transferase c. gene product produces a serum protein product that has no known enzymatic activity |
C.
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"B" gene product produces:
a. 1,3-N acetylgalactosaminyl transferase b. 1,3-galactosyl transferase c. gene product produces a serum protein product that has no known enzymatic activity |
B.
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pt has the following phenotype, name the correct genotype(s):
1) O 2) A 3) B 4) AB |
1) OO
2) AA,AO 3) BB,BO 4) AB remember that ABO genes are codominant |
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When do anti-A and anti-B appear?
a. prior to birth b. at birth c. 2-3 months after birth d. 5-6 months after birth |
D
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Anti-A is produced by:
a. people with AB blood group b. people with A blood group c. people with B blood group d. people with O blood group e. A and B f. C and D |
F
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Anti-B is produced by:
a. people with AB blood group b. people with A blood group c. people with B blood group d. people with O blood group e. A and C f. B and D |
F
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Anti-AB is produced by:
a. people with AB blood group b. people with A blood group c. people with B blood group d. people with O blood group e. A and B f. C and D |
D
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No serums antibodies are made in:
a. people with AB blood group b. people with A blood group c. people with B blood group d. people with O blood group e. A and B f. C and D |
A
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Anti-A is produced by:
a. people with AB blood group b. people with A blood group c. people with B blood group d. people with O blood group e. A and B f. C and D |
F
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Anti-B is produced by:
a. people with AB blood group b. people with A blood group c. people with B blood group d. people with O blood group e. A and C f. B and D |
F
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Anti-AB is produced by:
a. people with AB blood group b. people with A blood group c. people with B blood group d. people with O blood group e. A and B f. C and D |
D
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No serums antibodies are made in:
a. people with AB blood group b. people with A blood group c. people with B blood group d. people with O blood group e. A and B f. C and D |
A
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Anti-A is mostly:
a. IgM b. IgG c. IgA d. a mixture of both IgM and IgG |
a
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Anti-B is mostly:
a.IgA b.IgM c. IgG d. mixture of IgA and IgM |
B
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T or F. Anti-A,B is a mixture of anti-A and anti-B immunoglobulins.
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F. Anti-a,b is a single antibody which reacts against both A and B antigens
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Anti-A,B is predominately:
a. IgA b. IgG c. IgM d. a mixture of IgG and IgM |
B
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Back typing is:
a. a way to measure the serum Ab's against specific ABO blood groups b. a way to measure the presence of specific ABO blood group antigens on RBCs c. a method of confirming presence or absence of Rh antigen on RBCs d. a method of confirming presence of antibodies to Rh antigen in blood serum |
A
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Forward typing is:
a. a way to confirm the presence of serum Ab's against specific ABO blood groups b. a way to measure the presence of specific ABO blood group antigens on RBCs |
B.
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How would a cell (forward) and serum (back) typing tests result in for a pt with blood ABO group type A?
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forward: anti-A positive, anti-B negative
back: A cells negative, B cells positive due to the presence of A antigen on rbc's and anti-B in the serum |
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How would a cell (forward) and serum (back) typing tests result in for a pt with blood ABO group type AB?
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forward: Anti-A positive, Anti-B positive
backward: A and B cells negative due to the presence of A and B antigen on rbc's and lack of any Ab's in the serum |
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How would a cell (forward) and serum (back) typing tests result in for a pt with blood ABO group type O?
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forward: anti-A and anti-B negative
back: A cells positive, B cells positive due to no ABO antigens present on rbc's and both anti-A and anti-B present in the serum |
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in cell (forward) typing, pt's cells are 4+ for anti-A and negative for anti-B.
in serum (Back) typing, pt's cells are negative for A cells, and 4+ for B cells. what is your interpretation? a. blood type A b. blood type B c. blood type O d. blood type AB |
A
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the most common ABO type, regardless of ethnic background is:
a. blood type A b. blood type B c. blood type O d. blood type AB |
C.
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A patient with type O blood would be able to receive rbc's from (choose as many as possible):
a. blood type A b. blood type B c. blood type O d. blood type AB |
C.
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a patient with blood type A would only be able to receive rbc's from (choose as many as possible):
a. blood type A b. blood type B c. blood type O d. blood type AB |
A, C
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A patient with type AB blood would be able to receive plasma from:
a. blood type A b. blood type B c. blood type O d. blood type AB |
D
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A patient with type B blood would be able to receive plasma from (select as many as possible):
a. blood type A b. blood type B c. blood type O d. blood type AB |
B,D
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A patient with type O blood would be able to receive plasma from (select as many as possible):
a. blood type A b. blood type B c. blood type O d. blood type AB |
all the above - a patient with type O blood has antibodies for A and B in serum. when the patient needs to receive plasma, the plasma can come from O (that makes sense), A and B (which will have anti-B and anti-A, respectively, which won't do anything to the O antigen rbcs). AB will have no antibodies present in serum, so that this serum, of course, is the universal donor.
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This blood type is known as the universal donor for rbc's:
a. blood type A b. blood type B c. blood type O d. blood type AB |
C. type O has no immunogenic antigens on its rbc surfaces, so it won't react with the serum Ab's of anyone else blood, regardless of type.
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This blood type is known as the universal recipient:
a. blood type A b. blood type B c. blood type O d. blood type AB |
D. type AB blood cells have no antibodies in serum, so whichever plasma type you give to a patient with type AB blood, they can accept it without an adverse transfusion reaction.
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This blood type is known as the universal donor when it comes to plasma:
a. blood type A b. blood type B c. blood type O d. blood type AB |
D. The plasma of type AB blood cells will have no Ab's. Therefore, this is the easiest serum to give to others as it will not produce any adverse transfusion reactions, regardless of recipient blood type.
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In clinical settings, which antigen is most associated with the Rh system?
a. D antigen b. C antigen c. E antigen d. B antigen |
A. D antigen is the most immunogenic (in other words, it matters the most when it comes to preventing transfusion reactions).
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In Rh typing, the lab results came back as follows: ABO blood type group A. No agglutination reaction when anti-D reagent was added to blood.
The patient's Rh type is: a. positive b. negative c. neither |
B.
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Of the following ethnic groups, which have the highest % of positive Rh phenotypes?
a. caucasians b. africans c. asians d. hispanics |
C. (99% of Asians are Rh positive)
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A genotype of Dd means:
a. Rh positive b. Rh negative c. neither |
A.
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A genotype of dd means:
a. Rh positive b. Rh negative c. neither |
B.
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A genotype of DD means:
a. Rh positive b. Rh negative c. neither |
A.
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Rh negative individuals acquire anti-Rh:
a. prior to birth b. at birth c. at pregnancy d. at transfusion of Rh positive RBCs e. two of the above (name them!) |
E. at pregnancy and at transfusion of Rh pos rbc's are one of the only reasons why a Rh negative individual will become sensitized (acquire anti-Rh). It never happens spontaneously, unlike RBO blood type antigens (which antibodies form at 5-6 months of age).
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To avoid conditions such as the hemolytic disease of the newborn associated with Rh, an Rh negative mother with no anti-D present in serum, after giving birth to an Rh positive baby, should receive Rh immunoglobulin:
a. at 28 weeks gestation b. within 72 hours after delivery c. within 1 week after delivery d. at 28 weeks gestation AND within 72 hours after delivery e. at 28 weeks gestation AND within 1 week after delivery |
D.
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You must be at least how old to donate blood in Texas?
a. 14 b. 15 c. 16 d. 17 |
D.
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Name the anticoagulant placed in blood collection tests to keep the blood from clotting:
a. methotrexate b. tPA c. GPIIb/IIIa inhibitor d. citrate |
D.
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What is the correct order of component preparation of blood components during a typical blood donation:
a. soft spin to separate platelets from plasma, hard spin to separate rbc from supernatant b. soft spin to separate rbc from supernatant, hard spin to separate platelets from plasma c. hard spin to separate rbc from platelet, soft spin to separate plasma from platelet d. soft spin to separate plasma from rbc, hard spin to separate platelet from plasma |
B.
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Which component of whole blood donation is primarily used to increase oxygen-carrying capacity?
a. red blood cell transfusion b. fresh frozen plasma transfusion c. platelet transfusion d. cryoprecipitate |
A. especially for anemic pts, packed RBC transfusions will help in increasing the amt of Hb and Hct.
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Which component of whole blood donations is typically used for patients with low fibrinogen or as a source of von Willebrand factor?
a. red blood cell transfusion b. fresh frozen plasma transfusion c. platelet transfusion d. cryoprecipitate |
D. cryoprecipitate is FFP that's thawed and then the precipitate is collected (hence, cryo-"precipitate.")
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Cryoprecipitate contains all of the following except:
a. fibrinogen b. fibrin c. fibronectin d. factors 8 and 13 e. von Willebrand factor |
B.
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Which of the following components of whole blood donation is typically used in patients that require prevention of over-bleeding?
a. red blood cell transfusion b. fresh frozen plasma transfusion c. platelet transfusion d. cryoprecipitate |
C. Platelet transfusions are useful to control/prevent bleeding associated with low platelet count or functional defects (one unit will increase 5,000 platelets!!).
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Platelet transfusions are useful for all of the following EXCEPT:
a. immune thrombocytopenic purpura (ITP) b. patients undergoing chemotherapy for leukemia c. aplastic anemia d. None of the above (they are all indications for platelet transfusions) |
A. not effective for ITP unless there's significant bleeding
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Platelet transfusion is counter-indicated for the following EXCEPT:
a. thrombotic thrombocytopenia purpura (TTP) b. thrombocytopenia c. heparin-induced thrombocytopenia (HIT) d. A and C |
B. platetlet transfusion is actually HARMFUL for TTP and HIT patients.
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Which of the following blood components is typically useful for increasing the level of clotting factors in factor-deficient patients:
a. red blood cell transfusion b. fresh frozen plasma transfusion c. platelet transfusion d. cryoprecipitate |
B.
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FFP is useful in the treatment to raise the levels of deficient clotting factors, EXCEPT:
a. factor VIII b. factor V c. factor IX d. A and C e. all the above |
D. factors 8 and 9 deficiencies (hemophilia A and B) have their own recombinant proteins that don't require FFP for therapy.
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