Hematology 12: Blood Bank

Front 1

T/F: ABO antigens are only present on RBCs

Back 1

false

Front 2

80% of people ___ ABO Ags. This is a ___ trait.

Back 2

secrete
AD

Front 3

ABO incidence in caucasians in descending order of frequency

Back 3

A+
O+
B+
AB+

Front 4

precursor ligand goes to ___ via ___

Back 4

H Ag
alpha-L-fucosyltransferase

Front 5

H Ag goes to B Ag via ___.

Back 5

alpha galactosyltransferase

Front 6

H Ag goes to A Ag via ___

Back 6

NAc-galactosaminyl transferase

Front 7

people with type A blood have ___ (2) Ags

Back 7

A
H

Front 8

people with type B blood have ___ (2) Ags

Back 8

B
H

Front 9

Bombay phenotype is missing ___ so it has only ___ Ag

Back 9

alpha-L fucosyltransferase
precursor

Front 10

the direct Coombs test is aka ___. it checks the patient's ___ for ___.

Back 10

direct antiglobulin test
RBCs
bound Abs

Front 11

the indirect Coombs test is aka ___. it checks the patients ___ for ___.

Back 11

indirect antiglobulin test
serum
Abs

Front 12

Rh Ag is a ___. it is a tetramer composed of ___ or ___.

Back 12

transport protein
2RhAG + 2RhD
2RhAG + 2RhCE

Front 13

___% of caucasians, ___% of blacks and ___% of asians are Rh-

Back 13

15
5
1

Front 14

cold Abs are mostly ___, warm Abs are mostly ___

Back 14

IgM
IgG

Front 15

IgM usually cause ___ hemolysis via ___

Back 15

intravascular
complement

Front 16

IgG usually causes ___ hemolysis via __

Back 16

extravascular
macrophages

Front 17

reagent for DAT is ___. it detects ___ bound to ___s.

Back 17

anti-human globulin
IgG
RBC

Front 18

___ is a characteristic finding for intravascular hemolysis

Back 18

reticulocytosis

Front 19

3 diseases which can cause secondary autoimmune hemolysis

Back 19

CLL
malignant lymphoma
SLE

Front 20

autoimmune hemolysis tx (3)

Back 20

steroids
packed RBCs
folic acid

Front 21

prophylaxis againt hemolytic disease of newborn

Back 21

anti-D IgG injections for mother

Front 22

Tx of HDN for baby

Back 22

exchange transfusion
UV to help indirect bilirubin excretion

Front 23

T/F: post transfusion Abs are found in serum
T/F: post transfusion Abs are found on RBCs

Back 23

true
false

Front 24

T/F: post pregnancy Abs are found in serum
T/F: post pregnancy Abs are found on RBCs

Back 24

true
false

Front 25

T/F: HDN baby has Abs in serum
T/F: HDN baby has Abs on RBCs

Back 25

true
true

Front 26

T/F: AIHA has Abs in serum
T/F: AIHA has Abs on RBCs

Back 26

maybe
true

Front 27

if Rh- mother has already developed a high titer of of anti-D Abs, tx is ___. this works by ___ing.

Back 27

high dose anti-IgG
blocking MQ FcRs

Front 28

in contrast to ABO, anti-D Abs are ___. this is because ABO are ___, whereas D is ___.

Back 28

IgG
carbohydrate
protein

Front 29

if mother of HDN baby is negative for anti-D, check for ___

Back 29

anti-Yta

Front 30

prophylaxis against HDN is ___ at weeks ___ (2) and at birth

Back 30

500 iu progninin (anti-D IgG)
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