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16 Cards in this Set
- Front
- Back
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aplastic anemia is ___penia caused by ___.
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pan cyto
defective hematopoiesis |
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2 causes of defective hematopoiesis in AA
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stem cell failure due to intrinsic damage
autoimmunity against stem cells |
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3 scenarios for AA
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acquired
idiopathic congenital |
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most common scenario for AA is
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idiopathic
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4 causes of acquired AA
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drugs
radiation chemicals viral |
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5 drugs which cause AA
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chemotherapy
sulfa choramphenicol indomethacin gold |
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3 chemicals which cause AA
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benzene
insecticides hair dyes |
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virus which causes AA
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HAV
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anemia in AA is ___cytic and ___chromic
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normo
normo |
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retic count in AA is ___
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<1%
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3 criteria for AA
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neutrophils < 500/uL
platelets < 20,000/uL retics < 20,000/uL (<1%) |
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___ of the criteria are needed to diagnose AA
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at least 2
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"super severe" AA is defined by ___
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neutrophils < 200/uL
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3 parts of supportive tx for AA
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RBC transfusion
platelet transfusion aggressive antibiotics |
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2 parts of definitive tx for AA
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immunosuppression
allogeneic SC transplant |
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2 kinds of immunosuppressive tx for AA
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anti thymocytic globulin
cyclosporine |
