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40 Cards in this Set

  • Front
  • Back
Biological Findings for Anxiety and Panic disorders
Associated with epinephrine, NE, dopamine, serotonin, and GABA

Benzodiazepine receptors are linked to a receptor for inhibiting the neurotransmitter GABA, binding on these sites facilitates the release of GABA (GABA calms)
Biological findings for phobias
increased epinephrine
Biological findings for OCD
orbitofrontallimbic-basal ganglia circuit dysfunction; decreased serotonin
Biological findings for PTSD
reduced hippocampus

physical, sexual, or psychological abuse is associated with damaging effects to the brain.
Behavioral/ Learning Theory
All behaviors including anxiety are learned
Cognitive Theory
Anxiety is the result of distorted or faulty thinking patterns
Diagnostic criteria for Panic disorder (distinguish between 'panic disorder with agoraphobia' and 'panic disorder without agoraphobia')
a. recurrent episodes of panic atakcs
b. at least one of the attacks has been followed by one month (or more) or the following:
1. Persistent concern about having additional attacks
2. Worry about consequences of another attack
3. Significant change in behavior
Diagnostic criteria for Phobia
1. Irrational fear of an object or situation that persists although the person may recognize it as unreasonable
Agoraphobia
fear of being alone inopen o public places where escape might be difficult - may not leave home
Social phobia
Fear of situations where one might be seen and embarrassed or criticized; speakcing to authority figures, public speaking, or performing
Specific Phobia
Fear of a single object, activity, or situation (snakes, closed spaces, flying)

*Anxiety is severe if the object, situation, or activity cannot be avoided.
Diagnostic criteria for Obsessive Compulsive Disorder
Either obsessions or compulsions
A. repoccupation with persistent intrusive thoughts, impulses, or images (obsession)
B. Repetitive behaviors or mental acts that athe person jeels driven to perform in order to reduce distress or prevent a dreaded event or situation (compulsion).

2. Person knows the obsessions/ compulsions are excessice and unreasonable.
3. The obsession/ compulsion can cause increased distress and is time consuming
Diagnostic Criteria for Generalized Anxiety Disorder
1. A. Excessive anxiety or worry more day than not over 6 months
B. Cannot control the worrying

2. Anxiety and worry associated with 3 or more of:
A. restlessness
B. easily fatigued
C. Difficulty concentrating, mond goes blank
D. Irritability
E. Muscle tension
F. Sleep dsturbance

3. Anxiety or worry of physical symptoms cause significant impairment in social, occupational, or other areas of important functioning.
Physical Effects of Anxiety - sympathetic activation
1. Sweating
2. Chest pain
3. Dizziness
4. Decreased sex drive
5. Irritability
6. Increased muscle tension
7. Rapid breathing and breathlessness
8. Heart palpitations
9. Increased blood pressure
10. Nausea/ Diarrhea
Therapeutic Management: Behavioral Therapies
1. Systematic Desensitization
2. Flooding
3. Aversion Therapy - sidetracking
4. Thought Stopping
5. Structure and routine
6. Relaxation training
7. Modeling techniques
8. Positive reinforcement
Define Obsession
Thoughts, impulses, or images that persist and recur, so that they cannot be dismissed from he mind.
Define Compulsion
Ritualistic behaviors that an individual feels driven to perform in an attempts to reduce anxiety.
What are some common obsessions/ compulsions?
1. Doubt/ need to check
2. Sexual imagery or ideation
3. Need for order
4. Violence
5. Germs/dirt
6. Illness or death
7. Counting
8. Touching
9. Washing or cleaning
10. Avoidance
11. Doing or undoing
12. Symmetry
Therapeutic Management: Cognitive Approaches
1. journal keeping
2. Priority restructuring
3. Cognitive reframeing
4. Assertiveness training
What are some medical conditions that could cause symptoms similar to an anxiety disorder?
1. pheochromocytoma - tumor within the endocrine system
2. pulmonary embolism
3. cardiac dysrhythmias
4. COPD
5. Mitral Valve prolase - presents just like a panic attack
Therapeutic Management: Lifestyle (self-care)
1. Nutrition and fluid intake
2. Hygiene and grooming
3. Elimination
4. Sleep and exercise
Pharmacological interventions for Anxiety Disorders
1. Benzodiazepines
2. Tricyclic Antidepressants (TCA)
3. Selective Serotonin Reuptake Inhibitors (SSRI)
4. Buspirone
5. Others
Benzodiazepine
Used in treatment of anxiety

Advantages: Rapid, few cardiac effects, cheap

Disadvantages: side effects, abuse potential (only used short term)
Tricyclic Antidepressants
Used in treatment of panic attacks, phobias, and PTSD

Advantages: single dosing, antidepresant

Disadvantages: delayed onset, anticholinergic effects - SLUD, decreased heart rate
Selective Serotonin Re-uptake Inhibitors
Used in treatment of OCD, panic, agoraphobia, GAD, mixed anxiety and depression

Advantages: single dosing, antidepressnat

Disadvantages: delayed onset, insomnia/ irritability
Buspirone
Used in treatment of anxiety

Advantages: no dependence, few side effects, no sedation, slow onset

Disadvantages: cost
DSM-IV-TR criteria for all anxiety disorders
1. Prominent: anxiety, panic attacks, or obsessions/ compulsions
2. Not directly due to medical condition
3. Not exclusive to delirium episode
4. Not better accounted for by another mental disorder
5.SIGNIFICANT distress or impairment
Panic Disorder
* 50% develop before age 24
* Twice as many women than men
* Comorbidity with depression and substance abuse - 30% abuse ETOH, 17% abuse cocaine, marijuana and other
* 1/3 develop agorophobia
* Decreased NE, decreased GABA
Treatment of choice for Panic Disorder
1. Cognitive-Behavioral therapy - sytematic desensitization and thought stopping
2. Decrease anxiety - relaxation
3. TCA (possibly with short-acting bezo- combo) or SSRI
4. MAOI
Phobias
* Affects twice as many women than men
* Higher propotion of men seek help
* Onset in childhood and adolescence - rarely after age 25
* Comorbid with depression (upto 25%) substance abuse in this population
Social Phobias
1. Speaking in public
2. Eating in front of others
3. Using a public bathroom
4. Writing in front of others
5. Answering questions
Specific Phobia Criteria
1. A marked and persistent fear that is excessive or unreasonable, that is cued by a specific object or situation
2. Exposure to the phobic stimulus almost invariably provokes immediate anxiety response
3. The object or situation is avoided or endured with intense anxiety
Treatments for specific phobias
In addition to basic anxiety reducing interventions
1. Systematic desensitization
2. Flooding
3. PRN beta blockers (specific: social)
4. SSRI's
Obsessive Compulsive Disorder
* 10-30% of population
* Men and women effected equally
* One of the top 10 leading causes of diability in established marker economies worldwide
* Up tp 67% have comorbid depression
*increased serotonin
*Decreased size caudate
*basal ganglia and cingulum
OCD treatment
1. Behavioral therapy
2. Pharmacological: Luvox (fluvoxamine) - SSRI
3. TCA's: anafranil, Imipramine
4. Surgical - rare, cingulotomy
Generalized Anxiety Disorder Treatment
1. Cognitvie-Behavioral therapy
2. Cognitive reframing
3. Stress management
4. Lifestyle modification
5. Support groups
6. Buspirone
7. Valium (diazepam)
8. TCA's (impipramine)
9. SSRI's
Post-Traumatic Stress Disorder
* More likely in women
* Can develop in childhood
* 30% of combat veterans
* Persons sujected to: natural and man-made disasters, violence, and terrorism
*Comorbid diagnosis - depression, sustance abuse, other anxiety disorders
*Can be prevented through crisis intervention
Risk factors for developing PTSD
1. Very young/ very old
2. Assault/ witness to assault
3. History of abuse
4. Sustance abuse (or other poor coping strategies)
5. Pre-existing emotional/ behavioral difficulties
Diagnostic Indicators and Symptoms of PTSD
PERSISTENT:
1. re-experiencing of trauma
2. Avoidance
3. Numbing of responsiveness
4. Symptoms of increased arousal
PTSD long-term interventions
1. Grief therapy
2. Support groups
3. Cognitive-Behavioral combination
4. TCA's and MAOI's = most helpful
5. SSRI's (last choice)
6. Benzo's not recommended because of risk of dependency