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78 Cards in this Set

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  • Back
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Blood is made of two main components:

Formed elements and plasma

The percentage of formed elements and plasma in blood:

FE: 45%


Plasma: 55%

What is basic blood volume for male and female?

Male: 5-6 mL


Female: 4-5 mL

What is hematocrit?

The percentage of your blood made of RBCs

Plasma is seen as the _____ fluid of blood.

Sticky, straw-colored

Plasma is made up of ______ water.

90%

What does formed elements consist of?

WBC, RBC, platelets

What are the three main plasma proteins?

Albumin, globulin, fibrinogen

Which plasma protein is most abundant and what is its function?

Albumin, 60-80%


Colloid osmotic pressure that removes water from tissue into capillaries

Function of globulin( alpha, beta, gamma):

Alpha: transports enzymes


Beta: transports proteins


Gamma: immunoglobulin, functions in immunity

Erythrocytes are produced in:

Red bone marrow

In the first trimester, what produces the stem cells for blood?

Yolk sac

Which protein stimulates the production of blood cells in red bone marrow?

Erythropoietin

What two places are erythropoietin produced?

90% in glomeruli of kidney


The rest in the liver

Two types of WBC and their types

Granulocytes: basophils, neutrophils , eosinophil


agrunolocytes: lymphocytes and monocytes

Which WBC makes up for 20-45% of the leukocytes?

Lymphocytes

Function of lymphocytes: T-cells and B-cells

T-cells: fights against foreign bodies


B-cells: produces antibodies

Which structure allows for leukocytes to reach the site of an infection?

Can move in an ameboid fashion

Monocytes are the __________ leukocytes.

Largest

What is release from basophils when there's an infection?

Histamine

What is another function of basophils?

Vasodilation, opens the blood vessel to allow WBC to go to the infected site

Eosinophil function:

Kill parasites and turn off allergic responses

Neutrophils and monocytes are:

Phagocytosis cells

Monocytes make up for what percentage of WBC?

4-8%

Another name for platelets is:

Thrombocytes

Function of platelets:

Helps in blood clotting; serotonin is released causing the blood vessel to construct and reduce the blood flow to the injured area

Increase in platelets causes:

Thrombosis

What type of blood cells do lymphoid and myeloid stem cells form?

Lymphoid produce lymphocytes


Myeloid produce all the other types of cells

Prior to erythrocytes there are:

Proerythroblast

________ enlarge to form monocytes.

Monoblasts

Granulocytes form from:

Myelocytes

Platelets originate from:

Megakaryocytes

Platelets originate from:

Megakaryocytes

What three factors do you need to form RBC and hemoglobin?

Folic acid, B12, iron

Thrombocytopenia occurs when there's a ___________ in platelets.

Decrease

What is destroyed during aplastic anemia?

Bone marrow

What is destroyed during aplastic anemia?

Bone marrow

Microcytic and macrocytic anemia is a deficiency in:

Microcytic: iron


Macrocytic: B12, folic acid

Polycythemia is the ________ of RBC.

Excess

Which organs form blood in the first two months?

Liver and spleen

Three layers of blood vessels are:

Tunica intima


Tunica media


Tunica externa

What are the structures of each blood vessel layer?

Tunica intima: simple squamous epithelium


Tunica media: smooth muscle


Tunica externa: connective tissue

What are three types of arteries?

Elastic arteries, muscular arteries and arterioles

Arteries have _______ pressure than veins.

More

Pressure (mmHg) in aorta, SVC/IVC:

Aorta: 100 mmHg


SVC/IVC: 4 mmmHg

What are the two types of capillaries?

Low permeability and sinusoids

Where are sinusoid capillaries located and their feature?

Liver and spleen: wide and leaky

What layer of the blood vessel is thicker in the vein than artery?

Tunica externa

Sickle cell disease is the result of:

Inherited, abnormal hemoglobin S produced

Sickle cell disease is the result of:

Inherited, abnormal hemoglobin S produced

Treatment for sickle cell disease:

Folic acid

Sickle cell disease is the result of:

Inherited, abnormal hemoglobin S produced

Treatment for sickle cell disease:

Folic acid

Symptoms and signs of sickle cell disease:

Jaundice, fever, fatigue, paleness, increase HR, ulcers in lower leg, decreased growth, bone pain, abdominal pain

9

Sickle cell disease is the result of:

Inherited, abnormal hemoglobin S produced

Treatment for sickle cell disease:

Folic acid

Symptoms and signs of sickle cell disease:

Jaundice, fever, fatigue, paleness, increase HR, ulcers in lower leg, decreased growth, bone pain, abdominal pain

9

Where does leukemia start and what occurs?

Starts in the bone marrow; production of white blood cells that don't stop growing

Sickle cell disease is the result of:

Inherited, abnormal hemoglobin S produced

Treatment for sickle cell disease:

Folic acid

Symptoms and signs of sickle cell disease:

Jaundice, fever, fatigue, paleness, increase HR, ulcers in lower leg, decreased growth, bone pain, abdominal pain

9

Where does leukemia start and what occurs?

Starts in the bone marrow; production of white blood cells that don't stop growing

Four different types of leukemia:

Acute, chronic, lymphocytic, myelogenous

Sickle cell disease is the result of:

Inherited, abnormal hemoglobin S produced

Treatment for sickle cell disease:

Folic acid

Symptoms and signs of sickle cell disease:

Jaundice, fever, fatigue, paleness, increase HR, ulcers in lower leg, decreased growth, bone pain, abdominal pain

9

Where does leukemia start and what occurs?

Starts in the bone marrow; production of white blood cells that don't stop growing

Four different types of leukemia:

Acute, chronic, lymphocytic, myelogenous

What occurs in lymphocytic and myelogenous leukemia?

Lymphocytic; effects lymphocytes and produces mature WBC


myelogenous; effects myelocytes and produces immature and mature WBC

Sickle cell disease is the result of:

Inherited, abnormal hemoglobin S produced

Treatment for sickle cell disease:

Folic acid

Symptoms and signs of sickle cell disease:

Jaundice, fever, fatigue, paleness, increase HR, ulcers in lower leg, decreased growth, bone pain, abdominal pain

9

Where does leukemia start and what occurs?

Starts in the bone marrow; production of white blood cells that don't stop growing

Four different types of leukemia:

Acute, chronic, lymphocytic, myelogenous

What occurs in lymphocytic and myelogenous leukemia?

Lymphocytic; effects lymphocytes and produces mature WBC


myelogenous; effects myelocytes and produces immature and mature WBC

Treatment for leukemia:

Chemo


Radiation


Inteferon-A


SCT

Four types

Why does jaundice cause yellow skin?

Produces damaged RBC which releases hemoglobin which turns into bilubrin, turning the skin yellow

Symptoms of leukemia:

Bone pain


Fever and night sweats


Bleed easily


Headache


Loses weight


Weakness


Swollen lymph nodes in armpit and neck


Gets infected easily