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26 Cards in this Set
- Front
- Back
Heart failure is a failure of the heart to
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pump effectively to meet the metabolic needs of the body
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Heart failure mechanism
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a decrease in pumping ability and a decrease in cardiac reserve combined with the adaptive mechanism used to maintain cardiac output
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The adaptive mechanisms that contribute to heart failure are
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1st- sympathetic response then Frank Starling then Myocardial hypertrophic remodeling and natiuretic peptides
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What does the Frank Starling Mechanism do
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increases stroke volume by increasing LVEDV and is responsible for activating the Renin-Angiotensin Aldosterone system to increase preload
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How does the frank sterling mechanism do this
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increases the SV b/c/ the greater the volume of blood in the heart before contraction, the greater the volume of blood ejected from the heart.
so then Increased contractility (ejaction fraction)occurs from EDV stretch |
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Sympathetic nevous system activity does what
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releases catecholamines to increase sympathetic tone causing an increase in HR and contractions
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Myocardial hypertrophy and remodeling does is what
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the heart hypertrophies to improve work performance (volume in the ventricles are overloaded, the heart gets bigger so the volume decreases)
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Myocardial hypertrophy can result in
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changes and function that could result in increased morbidity and mortality over time
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Natiuretic peptides include what
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atrial, brain, and C-type natriuretic peptides
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Atrial natiuretic peptide is released from the atrial cell in response to increases of atrial stretching (holding more volume) and pressure to cause what
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cause diuresis and block renin-angiotensin mechanism
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Brain natriuretic peptides are stored in the VENTRICULAR cells and respond when ventricular pressures are increased
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they do the same, cause diuresis and block RA
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C-type natuiretic peptides are found in VASCULAR tissue and do what
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support BP
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levels of what are elevated in congestive heart failire and why?
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ANP and BNP b/c ventricular dysfunctions.
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Congestive heart failure is
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heart failure accompanied by congestion of the bodies tissues.
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Causes of congestive heart failure are because
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impaired cardiac function, those resulting in excess work demands
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Etiologies of congestive heart failure associated with impaired cardiac function by decreasing c/o or pumping ability:
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cardiomyopathies, myocarditis and MI's, valvular heart diease either stenotic or regurgitant, congenital defects and constrictive pericarditis.
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Etiologies of congestive heart failure associated with excess work demands
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increased pressure work by systolic HTN, pulmonary HTN, or coarctation of the aorta (stenosis), those involved with increased volume work: arteriovenous shunts and volume overloads, or those increasing perfusion works: thyrotoxicosis and anemia
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Systolic vs. Diastolic failure
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Systolic is a decrease in cardiac contractility and ejection fraction while diastolic has a smaller ventricular chamber size, ventricular hypertrophy, and poor ventricular compliance.
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RIght sided failure symptoms include
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Congestion of the peripheral tissues (edema), dependent edema and ascites, gi tract congestion (anorexia, gi distress, weight loss), and liver congestion: hepatomegaly and elevated LFT (liver function test)
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Right sided failure is associated with
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problems with venous return = backflow
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Left sided failure is a problem with
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pumping blood out to the body
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Left sided heart failure symptoms are
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decreased CO, activity intolerance, decreased tissue perfusions, pulmonary congestions, signs of hypoxemia (dyspnea, orthopnea, paroxymal nocturnal dyspnea) and pulmonary edema (tachypnea, cough with pink frothy sputum and hypoxemia)
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Left side shows what symptoms that Right side does not
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pulmonary symptoms
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Classifying heart failure by two guidelines that are
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NY heart classification (focus' on symptoms) whilte ACC/AHA guidelines (focus on structural defect)
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NY heart classification
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Class 1- ordinary, no fatigu, dyspnea or angina
Class 2- slight limitation of physical activity with ordinary activity angina, dyspnea, fatigue, but asymptomatic at rest Class 3- marked limitations of PA but still asymptomatic at rest Class 4- cant perform PA without symptoms, discomfort increases, and symptoms present at rest |
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ACC/AHA guidelines
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Stage A- at risk for HF but no structural heart disease signs/symptoms
Stage B- structural heart disease but no sign or symptoms Stage C- structural heart disease with prior/current signs Stage D- End stage disease needing special treatment such as mechanical support, continuous inotropic therapy and heart transplant |