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26 Cards in this Set

  • Front
  • Back
Heart failure is a failure of the heart to
pump effectively to meet the metabolic needs of the body
Heart failure mechanism
a decrease in pumping ability and a decrease in cardiac reserve combined with the adaptive mechanism used to maintain cardiac output
The adaptive mechanisms that contribute to heart failure are
1st- sympathetic response then Frank Starling then Myocardial hypertrophic remodeling and natiuretic peptides
What does the Frank Starling Mechanism do
increases stroke volume by increasing LVEDV and is responsible for activating the Renin-Angiotensin Aldosterone system to increase preload
How does the frank sterling mechanism do this
increases the SV b/c/ the greater the volume of blood in the heart before contraction, the greater the volume of blood ejected from the heart.
so then Increased contractility (ejaction fraction)occurs from EDV stretch
Sympathetic nevous system activity does what
releases catecholamines to increase sympathetic tone causing an increase in HR and contractions
Myocardial hypertrophy and remodeling does is what
the heart hypertrophies to improve work performance (volume in the ventricles are overloaded, the heart gets bigger so the volume decreases)
Myocardial hypertrophy can result in
changes and function that could result in increased morbidity and mortality over time
Natiuretic peptides include what
atrial, brain, and C-type natriuretic peptides
Atrial natiuretic peptide is released from the atrial cell in response to increases of atrial stretching (holding more volume) and pressure to cause what
cause diuresis and block renin-angiotensin mechanism
Brain natriuretic peptides are stored in the VENTRICULAR cells and respond when ventricular pressures are increased
they do the same, cause diuresis and block RA
C-type natuiretic peptides are found in VASCULAR tissue and do what
support BP
levels of what are elevated in congestive heart failire and why?
ANP and BNP b/c ventricular dysfunctions.
Congestive heart failure is
heart failure accompanied by congestion of the bodies tissues.
Causes of congestive heart failure are because
impaired cardiac function, those resulting in excess work demands
Etiologies of congestive heart failure associated with impaired cardiac function by decreasing c/o or pumping ability:
cardiomyopathies, myocarditis and MI's, valvular heart diease either stenotic or regurgitant, congenital defects and constrictive pericarditis.
Etiologies of congestive heart failure associated with excess work demands
increased pressure work by systolic HTN, pulmonary HTN, or coarctation of the aorta (stenosis), those involved with increased volume work: arteriovenous shunts and volume overloads, or those increasing perfusion works: thyrotoxicosis and anemia
Systolic vs. Diastolic failure
Systolic is a decrease in cardiac contractility and ejection fraction while diastolic has a smaller ventricular chamber size, ventricular hypertrophy, and poor ventricular compliance.
RIght sided failure symptoms include
Congestion of the peripheral tissues (edema), dependent edema and ascites, gi tract congestion (anorexia, gi distress, weight loss), and liver congestion: hepatomegaly and elevated LFT (liver function test)
Right sided failure is associated with
problems with venous return = backflow
Left sided failure is a problem with
pumping blood out to the body
Left sided heart failure symptoms are
decreased CO, activity intolerance, decreased tissue perfusions, pulmonary congestions, signs of hypoxemia (dyspnea, orthopnea, paroxymal nocturnal dyspnea) and pulmonary edema (tachypnea, cough with pink frothy sputum and hypoxemia)
Left side shows what symptoms that Right side does not
pulmonary symptoms
Classifying heart failure by two guidelines that are
NY heart classification (focus' on symptoms) whilte ACC/AHA guidelines (focus on structural defect)
NY heart classification
Class 1- ordinary, no fatigu, dyspnea or angina
Class 2- slight limitation of physical activity with ordinary activity angina, dyspnea, fatigue, but asymptomatic at rest
Class 3- marked limitations of PA but still asymptomatic at rest
Class 4- cant perform PA without symptoms, discomfort increases, and symptoms present at rest
ACC/AHA guidelines
Stage A- at risk for HF but no structural heart disease signs/symptoms
Stage B- structural heart disease but no sign or symptoms
Stage C- structural heart disease with prior/current signs
Stage D- End stage disease needing special treatment such as mechanical support, continuous inotropic therapy and heart transplant