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33 Cards in this Set

  • Front
  • Back
NSTEMI & UA
MONA +GAP-BA

Morphine
Oxygen
Nitrates
ASA/Plavix

GP 2b/3a REC INH
Anticoags
P2Y12 INH

BB
ACEI/ARBs
GP 2b/3a REC INH

8 CI?
Block platelet aggregation preventing thrombosis - REC INH is the binding site for fibrinogen

Thrombocytopenia (plt <100,000/mm3)
Hx of: bleed/CVA/stroke (w/in 30 days)
Active internal bleed
Recent surgery
Renal dysfxn
INC Prothrombin Time
Uncontrolled sev HTN
ReoPro

For?
Filter?
CI?
2 Primary SE?
Abciximab - GP 2b/3a REC INH

Only admin if PCI planned

Filter with administration

CI - Murine pp hypersensitivity

Bleeding
Thrombocytopenia
Integrilin
Eptifibatide - GP 2b/3a REC INH

CI - Renal dysfxn
Aggrastat
Tirofiban - GP 2b/3a REC INH

CI - Renal dysfxn
P2Y12 INH
INH platelet activation and aggregation
Plavix

For?
Dose?
LD if not stunting?
Red effectiveness?
DI?
Clopidogrel prodrug (irreversible bind) - Only admin if PCI planned

LD: 300-600mg (600mg for PCI)
MD: 75 mg QD

NO loading dose if not stenting

Poor met of 2C19 - RED effective

2C19 Substrate - Strong INH: PPI, Cimetidine, SSRI, Azole)
Effient

For?
Not REC for?
Prasugrel - prodrug (irreversible bind) - Only admin if PCI planned

>75 - NOT REC d/t intracranial bleed
Brilinta

Onset?
Red effectiveness?
DI?
Ticagrelor - not prodrug (reversible bind)

Faster onset

+ ASA >100mg/d - RED effectiveness of Brillinta

3A4 Substrate - Strong 3A4 INH: Statin (Simva, Lova)
STEMI
MONA + GAP - BA +/- Thrombolytics
THROMBOLYTICS
Fibrinolysis when bind to fibrin in a thrombus and convert entrapped plasminogen to plasmin

For: hospital can't perform PCI w/in 90 mins

Initiated - w/in 30 mins (arrival to the hospital)

Beneficial for STEMI - admin 12-24 hrs out from sx onset
t-PA
Alteplase
rt-PA
Alteplase
Activase
Alteplase
r-PA
Reteplase
Retevase
Reteplase
TNK-tPA
Tenecteplase
TNKase
Tenecteplase
Streptase
Streptokinase
ANTICOAG
Prevent further clotting
UFH
Heparin

Treatment of ACS/STEMI:
Bolus - 60 U/kg IV
Infusion - 12 U/kg/hr
Lovenox
Enoxaparin - LMWH

Treatment of UA/NSTEMI:
1 mg/kg SC Q12H or 1.5 mg/kg SC QD
<30 mL/min - 1 mg/kg SC QD

Treatment of STEMI (<75):
Bolus - 30 mg IV + 1 mg/kg SC
then 1 mg/kg SC Q12H

Treatment of STEMI (>75):
No Bolus - 0.75 mg/kg SC Q12H
Fragmin
Dalteparin - LMWH

Treatment of UA/NSTEMI:
120 U/kg Q12H
Innohep
Tinzaparin - LMWH
Arixtra
Fondaparinux
Refludan
Lepirudin - DRI (Direct Thrombin INH)
Argatroban
Ok - DRI
Angiomax
Bivalirudin - DRI
Ipravask
Desirudin - DRI
Pradaxa
Dabigatran - DRI Oral
Xarelto
Rivaroxaban
Coumadin
Warfarin
Jantoven
Warfarin