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49 Cards in this Set

  • Front
  • Back
3 rows of cells Located on outside of pillars (rods) of Corti
Outer Hair Cells
How many rows of outer hair cells have been reported near the apex?
4-5
Approximately how many outer hair cells in number?
12,500
Outer hair cells are shaped like a _____________
test tube
Stereocilia of outer hair cellsform ____ or ____ pattern
w, v
What are the 3 major types of supporting cells for Outer Hair Cells?
Deiters’ cells, Henson’s cells, Claudius cells
What are the two main parts of Deiter's cells?
main body that rests on BM and holds Outer Hair Cells & phalangeal process that projects to organ of Corti
Describe the cytoarchitecture of Inner Hair Cells.
extensive endoplasmic reticulum; golgi apparatus & mitochondria (suggestive of high metabolic levels)
The cytoarchitecture of Outer Hair Cells has a more extensive subsurface that is similar to _____________
muscle.
OHCs contain _____________, allowing cells to elongate and contract.
contractile proteins
Both IHCs and OHCs contain a thickened membrane called a ____________
cuticular plate
Both IHCs and OHCs have a noncuticular area containing a basal body of a ____________________
rudimentary kinocilium
The ____________ forms a continuous surface over the hair cells
Reticular lamina
What forms the reticular lamina?
cuticular plate, phalangeal processes, and tops of pillars
Highly vascularized tissue that provides nutrients to cochlea.
Stria Vascularis
What is the role of the stria vascularis?
Serves to maintain ionic composition of endolymph in cochlear duct and maintain an electrical potential (endolymphatic potential)
The stria vascularis contains a high concentration of __________ (suggesting ____________________)
mitochondria; high metabolic levels
A Semitransparent, gelatinous membrane that Extends over entire Organ of Corti
Tectorial Membrane
The Tectorial Membrane extends from _______________ where attachment is ________ to _____________ , where attachment is _________.
spiral limbus, strong, outer supporting cells (Henson’s cells and/or Deiters’ cells), loose
Which type of hair cells are embedded in the tectorial membrane?
Outer Hair Cells
Cochlea innervated by ____________________________
cn VIII (aud. Nerve or stato-acoustic nerve)
What are the 2 divisions of the auditory nerve?
vestibular
auditory
Approximately how many neurons exist in humans?
30,000
On its way to brain cn VIII passes through the ________________________________
Internal auditory canal
The internal auditory canal extends from the _____________ to ______________________
base of the cochlea, petrous portion of temporal bone
Cell bodies of CN VIII constitute the ______________, found in the modiolus
spiral ganglia
The majority of these neurons are ____________ neurons that carry sensory info from the hair cell to the brain.
Afferent
Some of the fibers are __________ neurons that carry information from brain to cochlea.
Efferent
What are Type 1 auditory neurons of the spiral ganglia?
large myelinated bipolar neurons
What are Type II auditory neurons of the spiral ganglia?
small unmyelinated pseudo-monopolar neurons
As fibers enter cochlea approximately 90-95% of fibers, which are called ______________ go to IHCs. Which type of neurons are these?
Inner radial fibers, Type I bipolar neurons
The remaining 5-10% fibers that don't go to IHCs are called ________________ and go to the OHCs. Which type of neurons are these?
Outer spiral fibers, Type II psuedo-monopolar neurons
The remaining 5-10% fibers that don't go to IHCs are called outer spiral fibers and go to the OHCs. Which type of neurons are these?
Type II pseudo-monopolar neurons
Nerve fibers may be myelinated or unmyelinated before exiting the ___________________
habenula perforata(e)
once nerve fibers enter into cochlea they are all _________________-
unmyelinated
When compared to neurons, axons to the OHCs take a more __________ course
oblique
Describe the shape of the auditory nerve.
Auditory nerve is a twisted trunk
The core of the auditory nerve is made up of _____________________
fibers from the cochlear apex
The Auditory Nerve exits cochlea and courses thru __________________
internal auditory canal
The auditory nerve enters brain at ______________
lower pons
Spiral ganglion cells represent _____________ neurons
first order
The pathways of the auditory nerves are complex. Some fibers course in an ____________ fashion and others _____________
ipsilateral, contralaterally
Fibers are labeled according to _______________________________
# of synapses (connnections)
__________________ auditory nerve fibers project to the lateral regions of the cochlear nucleus
Low frequency
CN VIII fibers are called ___________
first order
As first order fibers enter the brainstem they synapse with cell bodies in the ________________________
dorsal and ventral cochlear nucleus
2nd order neurons arise from ______________________
cochlear nuclei
Low frequency auditory nerve fibers project to the____________________ of the cochlear nucleus
lateral regions
_____________________ auditory fibers project to the the medial regions of the dorsal cochlear nucleus (DCN) and posterior ventral cochlear nucleus (PVCN) and to the medial and dorsal anterior ventral cochlear nucleus (AVCN)
High frequency