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49 Cards in this Set
- Front
- Back
3 rows of cells Located on outside of pillars (rods) of Corti
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Outer Hair Cells
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How many rows of outer hair cells have been reported near the apex?
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4-5
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Approximately how many outer hair cells in number?
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12,500
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Outer hair cells are shaped like a _____________
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test tube
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Stereocilia of outer hair cellsform ____ or ____ pattern
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w, v
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What are the 3 major types of supporting cells for Outer Hair Cells?
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Deiters’ cells, Henson’s cells, Claudius cells
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What are the two main parts of Deiter's cells?
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main body that rests on BM and holds Outer Hair Cells & phalangeal process that projects to organ of Corti
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Describe the cytoarchitecture of Inner Hair Cells.
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extensive endoplasmic reticulum; golgi apparatus & mitochondria (suggestive of high metabolic levels)
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The cytoarchitecture of Outer Hair Cells has a more extensive subsurface that is similar to _____________
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muscle.
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OHCs contain _____________, allowing cells to elongate and contract.
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contractile proteins
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Both IHCs and OHCs contain a thickened membrane called a ____________
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cuticular plate
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Both IHCs and OHCs have a noncuticular area containing a basal body of a ____________________
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rudimentary kinocilium
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The ____________ forms a continuous surface over the hair cells
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Reticular lamina
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What forms the reticular lamina?
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cuticular plate, phalangeal processes, and tops of pillars
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Highly vascularized tissue that provides nutrients to cochlea.
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Stria Vascularis
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What is the role of the stria vascularis?
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Serves to maintain ionic composition of endolymph in cochlear duct and maintain an electrical potential (endolymphatic potential)
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The stria vascularis contains a high concentration of __________ (suggesting ____________________)
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mitochondria; high metabolic levels
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A Semitransparent, gelatinous membrane that Extends over entire Organ of Corti
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Tectorial Membrane
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The Tectorial Membrane extends from _______________ where attachment is ________ to _____________ , where attachment is _________.
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spiral limbus, strong, outer supporting cells (Henson’s cells and/or Deiters’ cells), loose
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Which type of hair cells are embedded in the tectorial membrane?
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Outer Hair Cells
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Cochlea innervated by ____________________________
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cn VIII (aud. Nerve or stato-acoustic nerve)
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What are the 2 divisions of the auditory nerve?
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vestibular
auditory |
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Approximately how many neurons exist in humans?
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30,000
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On its way to brain cn VIII passes through the ________________________________
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Internal auditory canal
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The internal auditory canal extends from the _____________ to ______________________
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base of the cochlea, petrous portion of temporal bone
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Cell bodies of CN VIII constitute the ______________, found in the modiolus
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spiral ganglia
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The majority of these neurons are ____________ neurons that carry sensory info from the hair cell to the brain.
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Afferent
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Some of the fibers are __________ neurons that carry information from brain to cochlea.
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Efferent
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What are Type 1 auditory neurons of the spiral ganglia?
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large myelinated bipolar neurons
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What are Type II auditory neurons of the spiral ganglia?
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small unmyelinated pseudo-monopolar neurons
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As fibers enter cochlea approximately 90-95% of fibers, which are called ______________ go to IHCs. Which type of neurons are these?
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Inner radial fibers, Type I bipolar neurons
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The remaining 5-10% fibers that don't go to IHCs are called ________________ and go to the OHCs. Which type of neurons are these?
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Outer spiral fibers, Type II psuedo-monopolar neurons
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The remaining 5-10% fibers that don't go to IHCs are called outer spiral fibers and go to the OHCs. Which type of neurons are these?
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Type II pseudo-monopolar neurons
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Nerve fibers may be myelinated or unmyelinated before exiting the ___________________
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habenula perforata(e)
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once nerve fibers enter into cochlea they are all _________________-
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unmyelinated
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When compared to neurons, axons to the OHCs take a more __________ course
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oblique
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Describe the shape of the auditory nerve.
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Auditory nerve is a twisted trunk
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The core of the auditory nerve is made up of _____________________
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fibers from the cochlear apex
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The Auditory Nerve exits cochlea and courses thru __________________
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internal auditory canal
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The auditory nerve enters brain at ______________
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lower pons
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Spiral ganglion cells represent _____________ neurons
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first order
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The pathways of the auditory nerves are complex. Some fibers course in an ____________ fashion and others _____________
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ipsilateral, contralaterally
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Fibers are labeled according to _______________________________
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# of synapses (connnections)
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__________________ auditory nerve fibers project to the lateral regions of the cochlear nucleus
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Low frequency
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CN VIII fibers are called ___________
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first order
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As first order fibers enter the brainstem they synapse with cell bodies in the ________________________
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dorsal and ventral cochlear nucleus
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2nd order neurons arise from ______________________
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cochlear nuclei
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Low frequency auditory nerve fibers project to the____________________ of the cochlear nucleus
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lateral regions
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_____________________ auditory fibers project to the the medial regions of the dorsal cochlear nucleus (DCN) and posterior ventral cochlear nucleus (PVCN) and to the medial and dorsal anterior ventral cochlear nucleus (AVCN)
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High frequency
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